Background: Type 2 diabetes has increased risk of heart failure 2-4 times more than those in non-diabetic subjects. The early detection of asymptomatic ventricular dysfunction by using NT-pro BNP test in diabetic patients is the best strategy for decreasing morbidity and mortality of heart failure. Aim: The aims of this study were to detect asymptomatic cardiac ventricular dysfunction by using NT-pro BNP test in subjects with type 2 diabetes and to define the factors associated with elevated NT-proBNP. Materials and Methods: This cross-sectional study was included diabetic and non diabetic subjects aged from 35- to 64 years, who had no clinical symptoms of heart failure. Cardiovascular risk factors were detected by clinical examinations. NT-pro BNP determination was performed on an immunoassay analyzer (FIA1100, Getein Bio Medical Inc, China), which uses reagent strip to obtain quantitative NT-pro BNP results in plasma. The cut-off point for NT-pro BNP was 300 pg/ml. Results: A total of 536 subjects without clinical symptoms of heart failure were included in the study of which, 150 were diabetic and 386 were non diabetic. The mean age was 52.8 ± 7.8 years and 281 (52.4%) were females. Cardiac ventricular dysfunction was detected in 7.3% of diabetic and 5.2% of non diabetic subjects. Cardiac ventricular dysfunction in diabetic subjects was increased with age and non-significantly higher in females than in males (8.3% vs 6.4%, p>0.05). In the logistic regression analysis, uncontrolled hypertension (OR 3.80, 95% CI 1.07–13.44), long duration of disease (OR 5.30, 95% CI 1.36-20.66), and ageing (OR 5.40, 95% CI 1.29–22.88) were significantly correlated cardiac ventricular dysfunction in subjects with type 2 diabetes. Conclusion Cardiac ventricular dysfunction in subjects with type 2 diabetes was detected 1.4 times more than those in non diabetic subjects. The likelihood of positive NT-pro BNP test in subjects with type 2 diabetes was independently (p<0.05) associated with advanced age, uncontrolled hypertension and long duration of diabetes.

Background: To evaluate changes in liver function in patients with alcohol use disorder and propose preventive measures. Methods: In this study, 118 people were examined between January 2024 to December 2024. Results were analyzed SPSS. Result: The mean subject age was 48.6± 10.3 years, male: female ratio was 5:1. Mean arterial pressure was 104±12.8 mmHg, ALT 86.7 ± 93.8 (U/L), AST 89.3±82.8 (U/L), GGT 213.8±252.3 (U/L). A statistically significant correlation was found between AST and ALT levels (R² = 0.562). However, no significant correlation was observed between body mass index (BMI) and blood glucose levels (R² = 0.002). The AST/ALT ratio was also statistically significant (p = 0.0001). Conclusion Excessive alcohol consumption increases the levels of liver enzymes AST 89.3 ± 82.8 (U/L), ALT 86.7 ± 93.8 (U/L), and GGT 213.8 ± 252.3 (U/L), leading to increased liver cell damage. Therefore, it is necessary to reduce alcohol consumption and implement preventive measures.

Postmenopausal estrogen deficiency can lead to genitourinary syndrome of menopause (GSM), which manifests as vaginal dryness, dyspareunia, and sexual dysfunction, among other clinical symptoms. These complications often result in emotional distress and a decline in overall quality of life (7). Several studies estimate that 25–50% of postmenopausal women experience symptoms such as pain during intercourse, burning, itching, and dysuria due to vaginal atrophy and inflammation (9). Menopause is commonly diagnosed based on the absence of menstruation and hormone levels (10), but one of the simplest diagnostic methods is the evaluation of the vaginal microenvironment. There is limited data in Mongolia regarding the vaginal microenvironment of perimenopausal and postmenopausal women and the factors influencing its changes. This gap in knowledge formed the basis of our study. The aim of this research was to assess the vaginal microenvironment in menopausal women and to analyze its relationship with various influencing factors. We conducted a cross-sectional observational study using a descriptive research design. A total of 110 women aged 45–55 years, presenting with menopausal symptoms at “Santmaral” Women’s Clinic and the Women’s Outpatient Department of Songinokhairkhan Health Center, were selected for the study. Both quantitative and qualitative research methods were employed, including surveys and physical examinations. Participants completed a 10-minute questionnaire consisting of 8 open-ended and 12 closed-ended questions. The vaginal microenvironment was assessed using special pH test strips applied to vaginal secretions. Data were analyzed using Excel 21 and SPSS 23, comparing the vaginal microenvironment with various influencing factors. The results showed that the average vaginal microenvironment pH among menopausal women was 5.18 ± 0.45 (n=110). In married women, the average pH was 5.1 ± 0.45; among women with a history of pregnancy, it was 4.10 ± 1.58; and among those who had given birth, it was 2.8 ± 0.98 — indicating an abnormal vaginal microenvironment. Women who were using hormone replacement therapy had an average pH of 5.05 ± 0.45, while those using non-hormonal contraceptive methods had an average pH of 5.3 ± 0.43. These findings were statistically significant (p = 0.0001****)

Background Cancer remains one of the leading causes of death worldwide, with 19.3 million new cases recorded in 2020 and an estimated 28.4 million by 2040. In Mongolia, it ranks second after cardiovascular diseases in terms of mortality. Receiving a cancer diagnosis significantly impacts not only the physical condition of patients but also their psychological and social well-being. Studies indicate that 35–50% of cancer patients experience symptoms of depression, anxiety, and post-traumatic stress. This study aims to determine the stress levels of cancer patients and investigate the relationships between the factors that influence these levels. The Self-Report Questionnaire (SRQ-20), developed by the WHO for primary healthcare physicians, was officially approved and used in this study. In terms of gender distribution, the majority were female (69.8%), while males accounted for 30.2%.
According to the study, in stage I of cancer, 9.5% of patients experienced high stress, 14.3% had moderate stress, and 7.9% reported no stress. In stage II, 9.5% had high stress, 22.2% had moderate stress, and 11.1% had no stress. In stage III, 6.3% experienced high stress, 9.5% had moderate stress, and 3.2% reported no stress. In stage IV, 4.8% experienced high stress, and 1.6% had moderate stress; no patients in this stage reported being stress free.
The highest percentages of moderate stress were observed in stages I and II (14.3% and 22.2%, respectively), possibly due to the strong emotional reaction at the time of initial diagnosis. In contrast, all stress levels declined sharply in stages III and IV, with 6.3% experiencing high stress, 9.5% moderate stress, and 3.2% no stress in stage III. In stage IV, 4.8% had high stress and 1.6% moderate stress, while no patients reported being stress-free.

The global average cancer incidence is 9.3 per 100,000 population, while this figure is 93.7, or 10 times higher, in our country. At the end of the 2023 report, 28,855 people were being monitored and treated for cancer under the supervision of the province's district oncologists. According to the 2022 statistics of the World Health Organization, about 10 million people die from this disease every year in the world. In Mongolia, the incidence and mortality rate of cancer have also increased rapidly in recent years, and as of 2021, it has become the second leading cause of death.
To determine the level of depression in cancer patients and study the relationship between some factors affecting it research methods and scope: The study was conducted using a single-point analytical research design, and data were collected from 95 cancer patients under the care of a family health center between February 10, 2025 and March 20, 2025 using the PHQ 9, 18 Sleep Disorders Questionnaires, and 15 General Information Questionnaires, a total of 42 questionnaires issued by the WHO for primary health care providers. 26.3% (25) of the study participants were male, and 73.7% (70) were female. Of the total study participants, 39 (41.1%) were not depressed, 25 (26.3%) had self-limiting depression, 15 (15.8%) had moderate depression, 3 (3.2%) had moderate to severe depression, and 13 (13.7%) had severe depression. The majority of cancer patients are depressed. Severe depression can make it difficult to perform simple social activities and may even lead to suicide, so psychiatric evaluation, diagnosis, and treatment are necessary.