Background: Anterior open bite involving the anterior dentition associated with skeletal Class III malocclusion is a severe dentofacial deformity resulting from discrepancies in vertical and sagittal relationships of the maxilla and mandible. In adult patients, orthodontic treatment alone is insufficient to achieve satisfactory outcomes; therefore, combined orthodontic and orthognathic surgical treatment is required. Case Presentation: A 21-year-9-month-old female patient presented with a chief complaint of mandibular prognathism. Clinical and radiographic examinations revealed anterior open bite involving the anterior dentition associated with skeletal Class III malocclusion. The treatment was carried out in three phases. Presurgical orthodontic treatment was performed to achieve dental decompensation, followed by orthognathic surgery. Le Fort I osteotomy was performed to reduce the vertical height by 3 mm and advance the maxilla by 5 mm, while bilateral sagittal split osteotomy (BSSO) was performed to set back the mandible by 9 mm. Post-surgical orthodontic treatment was performed using temporary anchorage devices (TADs) to provide stable anchorage, allowing precise control of tooth movement, and intermaxillary elastics were used to refine occlusion. As a result, facial profile, skeletal relationships, and occlusion were improved, with stable outcomes achieved. Diagnosis: Extraoral examination revealed a mandibular facial profile, increased height of the lower third of the face, normal facial midline at the nose, and a 1.5 mm leftward deviation at the chin. Lip position was -6 mm for the upper lip and -2 mm for the lower lip relative to the nasolabial angle. The angle between the cheekbones and the lips was 55.5°. Conclusion Combined orthodontic and orthognathic surgical treatment provides effective and stable outcomes in terms of esthetics, function, and occlusal stability in adult patients with anterior open bite associated with skeletal Class III malocclusion.

Background: Sexually transmitted infections (STIs) remain a major public health concern worldwide. Aim: This study aimed to determine the epidemiological patterns of sexually transmitted infections (STIs) reported in Mongolia. Materials and Methods: A retrospective cross-sectional design was employed, utilizing surveillance data on STIs and polymerase chain reaction (PCR) testing results from a total of 72 health facilities. Results: The findings indicate that the overall prevalence of STIs in the general population has not declined and remains consistently high. The most commonly reported infections-syphilis (10.8–15.0), gonorrhea (9.1–11.4), trichomoniasis (7.0–8.2), and chlamydial infection (0.1–0.8)-have shown persistently elevated rates over the study period. Furthermore, STI morbidity was significantly higher among individuals aged 20–39 years, representing the sexually active population, as well as among those with complete secondary education, those who were married, and those who were employed (p<0.001). Conclusion An important finding of this study is that although the number of real-time PCR tests conducted for STI detection and the corresponding positivity rate increased from 0.9% to 9.5%, the proportion of reported cases remains relatively low. This suggests limited accessibility to PCR diagnostics and insufficient reporting and surveillance of STIs. These findings highlight the need to strengthen laboratory diagnostic capacity, as well as to improve integrated surveillance and reporting systems, in order to effectively reduce the burden of STIs at the national level.

Association between diagonal earlobe crease (DELC), also known as Frank’s sign and CAD was first found by Sanders T. Frank in 1973. Since its first description, others have shown it to be associated with the presence, as well as the extent and severity of CAD, independent of traditional CAD risk factors, such as serum lipids, diabetes mellitus, and smoking status.DELC is also associated with higher risk of major adverse cardiac events in patients with known CAD.Recent studies have suggested that DELC may also be a marker of generalized atherosclerotic disease. This study evaluates the association between the presence of diagonal earlobe creases (DELC) and coronary artery disease (CAD). Four hundred people (246 men and 154 women, aged 28 to 92 years) were examined for the presence of DELC.400 people participated. In case group 200 people(142 men and 58 women, aged 30-87) who were getting treatment at State’s central 3rd hospital participated. In control group 200 people(104 men and 96 women, aged 28-92 who were getting treatment at State’s central 3rd hospital, National Traumatology Center included.We did statistic processing with MS Excel 2013, SPSS 20.0 DELC was present in 164 patients (82%) and absent in 36 patients (18%) of 200 participants documented with CAD (presence of > or = 50% coronary diameter stenosis at angiography). DELC was present in 42 people (21%) and absent in 158 people (79%) of 200 people documented without CAD. 82% of individuals with CAD had DELC. There was significant association between diagonal earlobe crease (DELC) and coronary artery disease (CAD), (p=0.039).

Introduction: This plants distributed about 2500 species in worldwide and 69 species of those grow in Mongolia. In case of medicinal application of this plant is commonly used traditional medicine in European and Asian. For example, the different preparations of Astragalus mongholicus root, the most commonly used Astragalus species in Chinese medicine. Other Astragalus species which are being investigated for their anti-cancer properties are the Turkish species, and include Astragalus brachypterus, Astragalus cephalotes, Astragalus microcephalus and Astragalus trojanus. Astragalus mongholicus.Bunge. Traditional Uses: The taste is sweet and the potency is hot. It is used for the following: treating light swelling, water swelling and phlegm, and improving physical energy and strength. It is also used to soothe a purulent inflammation, for wound-healing, to treat lung fever, oliguria and hemorrhoids. It is an ingredient of the following traditional prescription: Jurur-6 Chemical constituents: Root contains flavonoids: formononetin, 3-hydroxy-formononetin, 2,3- dihydroxy- 7,4-dimethoxyflavone, 7,3-dihydroxy-4-methoxyflavone 7-O- glucoside, 7,3-dihydroxy-4- dimethoxyflavone, saponins: astragaloside I-X, isoastragaloside I-IV, polysaccharides, Above- ground parts contain astragaloside quercetin, isorhamnetin, rhamnocetin, isorhamnetin 3-b-Dglucopyranoside, propingoside, coumarin, tannins, and saponins. Qualitative and quantitative assays: Flavonoids in the plant are identified by cyanidin reaction and reaction with lead tetraacetate. Total flavonoid content is determined by spectrophotometry at 430 nm and calculated as quercetin. Qualitative and quantitative standards: Loss on drying, 8.0%. Organic matter, not more than 0.5% and mineral matter, not more than 1.0%. Total flavonoid content, not less than 3.0%.