1.Effect of Traditional Medicine and Acupuncture Therapy on Postoperative Ileus Following Adhesive Small Bowel Obstruction
Undarmaa B ; Nasanhishig D ; Oyun-Erdene U ; Tserendulam G ; Anudari M ; Alzakhgui M ; Oyunbileg Yu ; Batchimeg N ; Enkhtuya V
Mongolian Journal of Health Sciences 2026;93(3):221-226
Background:
Adhesion small bowel obstruction (ASBO) is a common complication following abdominal surgery and can significantly impair postoperative recovery. This condition necessitates the exploration of more effective therapeutic approaches.
Aim:
The aim of this study was to evaluate the clinical efficacy of Traditional Mongolian Medicine (TMM) combined with acupuncture in the management of postoperative ileus secondary to adhesion-related small bowel obstruction.
Case Presentation:
We report the case of a 47-year-old female patient who developed postoperative ileus. The therapeutic intervention consisted of a combined regimen of traditional herbal pharmacotherapy and electroacupuncture. The clinical outcomes were assessed based on the resolution of symptoms and the restoration of gastrointestinal function.
Result:
Following the administration of the integrated treatment, the patient exhibited a marked reduction in abdominal pain. Objective clinical improvement was noted through the successful restoration of intestinal peristalsis and the normalization of flatus and defecation.
Conclusion
The findings of this case study suggest that Traditional Mongolian Medicine, particularly when integrated with electroacupuncture, may be an effective and viable modality for promoting the recovery of gastrointestinal motility in patients with adhesion-related small bowel obstruction.
2.Sex-specific differences in serum neurotrophic and neuromuscular biomarkers in older adults with Sarcopenia
Odgerel Ch ; Erdenesuvd B ; Altankhishig B ; Nomin-Erdene E ; Enguun E ; Saranzayaa S ; Bat-Erdene D ; Tulgaa S ; Munkh-Erdene U ; Nandin-Erdene M ; Oyun-Erdene R ; Tserenvandan Kh ; Ganbaatar B ; Munkhtsetseg J ; Buyankhuu T
Mongolian Journal of Health Sciences 2026;95(5):12-17
Background:
Sarcopenia is a multifactorial geriatric syndrome characterized by age-related loss of muscle mass, muscle strength, and physical performance. In recent years, neurotrophic and neuromuscular biomarkers have been investigated as potential diagnostic indicators of sarcopenia; however, evidence regarding their sex-specific differences remains limited.
Aim:
To evaluate the sex-specific associations of serum BDNF, GDNF, and CAF22 levels with sarcopenia and muscle-related parameters among older adults.
Materials and Methods:
This analytical cross-sectional study included adults aged 60 years and older. Sarcopenia was defined according to the Asian Working Group for Sarcopenia (AWGS 2019) criteria. Serum BDNF, GDNF, and CAF22 levels were measured using ELISA. Group differences were analyzed using independent t-tests, correlations were assessed using Pearson correlation analysis, and diagnostic performance for sarcopenia was evaluated using receiver operating characteristic (ROC) analysis. Multivariable logistic regression analysis was also performed.
Results:
No statistically significant differences were observed in serum BDNF, GDNF, and CAF22 levels between sarcopenic and non-sarcopenic participants in either the male or female groups (all p>0.05). ROC analysis demonstrated AUC values ranging from 0.540 to 0.542 in males and from 0.508 to 0.530 in females for BDNF, GDNF, and CAF22. Multivariable logistic regression analysis revealed that age (OR=1.12, 95% CI: 1.04–1.21, p=0.003) and lower fat-free mass index (OR=0.78, 95% CI: 0.66–0.91, p=0.001) were significantly associated with sarcopenia, whereas BDNF, GDNF, and CAF22 showed no independent association with sarcopenia.
Conclusions
1. No statistically significant sex-specific differences were observed in serum BDNF, GDNF, and CAF22 levels between sarcopenic and non-sarcopenic older adults (all p>0.05). 2. CAF22 levels were weakly negatively correlated with muscle mass and fat-free mass index in males (p<0.05), whereas BDNF levels showed weak positive correlations with handgrip strength and fat-free mass index in females (p<0.05). CAF22 levels also demonstrated a weak positive correlation with age (p<0.05). 3. ROC and multivariable logistic regression analyses indicated limited diagnostic utility of BDNF, GDNF, and CAF22 for sarcopenia (AUC=0.508–0.542), and none of these biomarkers showed an independent association with sarcopenia (all p>0.05). In contrast, older age (OR=1.12, p=0.003) and lower fat-free mass index (OR=0.78, p=0.001) were significantly associated with sarcopenia.
3.Calcium levels in 6-7-year-old children with electrocardiographic changes and their association with physical growth
Uurtsaikh M ; Khongorzul Ts ; Enkhtsolmon S ; Munkh-Erdene U ; Oyun-Erdene R ; Munkhtsetseg Sh ; Amraa G ; Odgerel Ch ; Munkhtsetseg J ; Tulgaa S
Mongolian Journal of Health Sciences 2026;97(7):60-65
Background:
A child’s physical growth is fundamentally dependent on hormonal regulation, metabolism, and oxygen supply, within which bone mineralization specifically calcium (Ca²⁺) levels acts as a primary factor determining bone mineral density (BMD), muscle function, and hormonal activity. In cardiovascular disease (CVD), multiple physiological processes are disrupted at various levels, including decreased blood circulation and oxygen supply, increased energy expenditure, and reduced absorption of nutrients and micronutrients. In this context, research linking calcium levels in 6–7-year-old children with electrocardiographic (ECG) changes to physical growth has been scarce, which provided the rationale for conducting this study.
Aim:
To investigate the association between calcium levels and physical growth among 6–7-year-old children with electrocardiographic (ECG) abnormalities detected through early screening.
Materials and Methods:
This study was conducted using a case-control design. The case group included 143 children aged 6–7 with ECG changes, and the control group included 153 children without ECG changes, totaling 296 voluntary participants. Serum total calcium and albumin levels in both groups were measured using a fully automated biochemical analyzer. Statistical analysis was performed using SPSSv27, applying independent samples t-tests, ANOVA, and correlation analysis to compare means between the two groups.
Results:
The control group’s serum total calcium was 2.65±0.15 mmol/L, corrected calcium was 2.58±0.13 mmol/L, and the case group’s serum total calcium was 2.64±0.18 mmol/L, corrected calcium was 2.59±0.17 mmol/L, with no statistically significant difference observed between the study groups (p>0.05). When comparing total calcium in case-group children with normal height (2.66±0.20) versus those with stunted growth (2.61±0.13), a statistically significant difference was found (p<0.05). Correlation analysis between total and corrected calcium levels and physical growth indicators across study groups showed no statistically significant association. When height measurements were divided into four quartiles (Q1–Q4) and compared against total and corrected serum calcium, no statistically significant differences were found between the groups.
Conclusions
Comparison of physical growth and development Z-scores between children with and without ECG abnormalities revealed no statistically significant differences. However, total calcium levels tended to be lower among children with normal growth compared with those with growth retardation in the case group (p < 0.05). No statistically significant differences were observed in serum total or albumin-corrected calcium levels between the study groups (p > 0.05). When height measurements in the study groups were categorized into quartiles, no statistically significant differences in total or albumin-corrected calcium levels were observed between the groups. This suggests that calcium levels alone may not be a decisive determinant of physical growth in children of the same age.
4.Cystatin C levels in left ventricular hypertrophy and chronic kidney disease secondary to arterial hypertension
Khongorzul Ts ; Otgonjargal Ch ; Munkh-Erdene U ; Odgerel Ch ; Oyun-Erdene R ; Nandin-Erdene M ; Buyankhuu T ; Munkhtsetseg J ; Tulgaa S
Diagnosis 2025;113(2):63-68
Background:
Identifying reliable biomarkers for early detection, risk stratification, and prognosis of CVD in the context of CKD is, therefore, of critical importance. Cystatin C has emerged as a potential biomarker capable of reflecting both cardiac injury and renal impairment, particularly in patients with arterial hypertension. This study aimed to evaluate the association between serum cystatin C levels, left ventricular hypertrophy, and chronic kidney disease in individuals with hypertension.
Objective:
To assess serum cystatin C concentrations in patients with left ventricular hypertrophy and chronic kidney disease secondary to arterial hypertension.
Materials and Methods:
A case-control analytical study was conducted, enrolling 44 patients aged 45 years or older with both left ventricular hypertrophy and chronic kidney disease due to arterial hypertension alongside a control group of apparently healthy individuals. Serum cystatin C levels were measured using immunoturbidimetric assay. Statistical analysis was performed using SPSS version 25.0. Group comparisons were made using independent-sample t-tests, while multivariate regression and receiver operating characteristic (ROC) analyses were employed to explore associations and the predictive value of cystatin C.
Results:
The mean serum cystatin C concentration in the case group was 1.6±0.1 mg/L, significantly higher than in the control group (0.88±0.03 mg/L, p<0.05). Similarly, the estimated glomerular filtration rate (eGFR) was markedly reduced in the case group (44.88±6.8 mL/min/1.73 m²) compared to the controls (92.88±3.4 mL/ min/1.73 m², p<0.05). In the case group, a statistically significant inverse correlation was observed between serum cystatin C levels and glomerular filtration rate (GFR), with a regression coefficient of β=−0.028 (p<0.006).
Conclusion
The elevated serum cystatin C levels (1.6±0.1 mg/L) and decreased eGFR (38.99±12.7 mL/min/1.73 m²) observed in the case group suggest that cystatin C may serve as a potential biomarker for the early diagnosis of left ventricular hypertrophy due to arterial hypertension and chronic kidney disease, as well as for predicting related complications.
5.Treatment of miniere’s disease (icd-10 h.81) using traditional medicine and therapeutic interventions: Case report
Undarmaa B ; Tserendulam G ; Oyun-Erdene U ; Oyunnyam Ch ; Nasankhishig D ; Khaliun E ; Tsegmed G ; Oyunbileg Yu ; Enkhtuya V
Mongolian Journal of Health Sciences 2025;87(3):72-74
Background:
Meniere's disease is a condition caused by disturbances in the
auditory and vestibular systems. It is characterized by symptoms such as dizziness,
nausea, vomiting, and tinnitus. In the United States, the prevalence of
Meniere's disease has been found to be 84 cases per 100,000 women and
56 cases per 100,000 men. Regionally, it is more common in less populated
areas, and research has confirmed that the prevalence increases with higher
household income.
Aim:
To evaluate the effectiveness of traditional medicine treatments and therapies
for Meniere's disease.
Results:
The patient is a 43-year-old male, with symptoms of dizziness, vomiting,
and tinnitus. Since 2023, he has sought care at the Central Hospital of
Mongolian Medicine, where he received traditional medicine treatments including
herbal therapy and other traditional therapies on three occasions. As a
result, the frequency of dizziness has decreased and other clinical symptoms
have improved.
Conclusion
Traditional medicine treatments have been shown to be effective
in managing Meniere's disease by extending the interval between relapses,
improving quality of life, and significantly reducing clinical symptoms.
6.Effects of some syrups on citric acid induced cough in rat
Munkh-Erdene R ; Davaasambuu V ; Bat-Oyun U ; Ahsholpan B ; Badamtsetseg S ; LKhaasuren R ; Hurelbaatar L
Mongolian Pharmacy and Pharmacology 2023;23(2):20-25
Abstract:
In Mongolia, flu and flu-like diseases affect many people, and pneumonia is a public health concern. Therefore, we have an urgent need to research and develop a new medicinal syrup to replace imported products using raw materials grown in Mongolia and to compare it with similar products. There are imported cough syrup products on the pharmaceutical market of Mongolia, but there are domestic pharmaceutical products. Moreover, there is limited research data on cough relief. The main goal of the research team is to compare the experimentally obtained syrup containing Plantago asiatica L, Malva Sylvestris L. and syrup containing Plantago major L. Juice, honey that produced by Monos Pharm LLC whish the cough relieving drug Gerbion syrup.
Material and methods:
The vivarium of the pharmacology laboratory, Drug research institute,
TPC7062Ti mark IVC system (Shanghai Pretty Industries Co.,Ltd, China) in a special environment
with one care and one feeding regimen (Lab Mice Diet, Constant Formula Balanced Nutrition,
Jiangsu Xietong Pharmaceutical Bio- Engineering Co., LTD, China, www.jsxtsw.com ) used 64
non-WISTAR white rats weighing 180-218 g. Experimental rats were smoked with an aerosol of
17% citric acid aqueous solution for 5 minutes. The statistical processing of the research results
was done using the One-Way ANOVA/Multiple comparisons data of the GraphPad Prism 8 program.
Results and conclusion
Expressing the number of coughs produced in the experimental rats as
a percentage (%), the control group showed 3.95% cough relief, and the experimental group-1 by
48.4%, experimental group-2 by 71.1%, comparison group by 74.6%, respectively has reduced.
Experimental group -2 and comparison group for dry cough caused by citric acid 17%, it affects
the cough receptors in the mucous membrane of the respiratory tract and relaxes the bronchial
muscles (A and C fiber).
Result Analysis
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