1.Treatment of miniere’s disease (icd-10 h.81) using traditional medicine and therapeutic interventions: Case report
Undarmaa B ; Tserendulam G ; Oyun-Erdene U ; Oyunnyam Ch ; Nasankhishig D ; Khaliun E ; Tsegmed G ; Oyunbileg Yu ; Enkhtuya V
Mongolian Journal of Health Sciences 2025;87(3):72-74
Background:
Meniere's disease is a condition caused by disturbances in the
auditory and vestibular systems. It is characterized by symptoms such as dizziness,
nausea, vomiting, and tinnitus. In the United States, the prevalence of
Meniere's disease has been found to be 84 cases per 100,000 women and
56 cases per 100,000 men. Regionally, it is more common in less populated
areas, and research has confirmed that the prevalence increases with higher
household income.
Aim:
To evaluate the effectiveness of traditional medicine treatments and therapies
for Meniere's disease.
Results:
The patient is a 43-year-old male, with symptoms of dizziness, vomiting,
and tinnitus. Since 2023, he has sought care at the Central Hospital of
Mongolian Medicine, where he received traditional medicine treatments including
herbal therapy and other traditional therapies on three occasions. As a
result, the frequency of dizziness has decreased and other clinical symptoms
have improved.
Conclusion
Traditional medicine treatments have been shown to be effective
in managing Meniere's disease by extending the interval between relapses,
improving quality of life, and significantly reducing clinical symptoms.
2.Cystatin C levels in left ventricular hypertrophy and chronic kidney disease secondary to arterial hypertension
Khongorzul Ts ; Otgonjargal Ch ; Munkh-Erdene U ; Odgerel Ch ; Oyun-Erdene R ; Nandin-Erdene M ; Buyankhuu T ; Munkhtsetseg J ; Tulgaa S
Diagnosis 2025;113(2):63-68
Background:
Identifying reliable biomarkers for early detection, risk stratification, and prognosis of CVD in the context of CKD is, therefore, of critical importance. Cystatin C has emerged as a potential biomarker capable of reflecting both cardiac injury and renal impairment, particularly in patients with arterial hypertension. This study aimed to evaluate the association between serum cystatin C levels, left ventricular hypertrophy, and chronic kidney disease in individuals with hypertension.
Objective:
To assess serum cystatin C concentrations in patients with left ventricular hypertrophy and chronic kidney disease secondary to arterial hypertension.
Materials and Methods:
A case-control analytical study was conducted, enrolling 44 patients aged 45 years or older with both left ventricular hypertrophy and chronic kidney disease due to arterial hypertension alongside a control group of apparently healthy individuals. Serum cystatin C levels were measured using immunoturbidimetric assay. Statistical analysis was performed using SPSS version 25.0. Group comparisons were made using independent-sample t-tests, while multivariate regression and receiver operating characteristic (ROC) analyses were employed to explore associations and the predictive value of cystatin C.
Results:
The mean serum cystatin C concentration in the case group was 1.6±0.1 mg/L, significantly higher than in the control group (0.88±0.03 mg/L, p<0.05). Similarly, the estimated glomerular filtration rate (eGFR) was markedly reduced in the case group (44.88±6.8 mL/min/1.73 m²) compared to the controls (92.88±3.4 mL/ min/1.73 m², p<0.05). In the case group, a statistically significant inverse correlation was observed between serum cystatin C levels and glomerular filtration rate (GFR), with a regression coefficient of β=−0.028 (p<0.006).
Conclusion
The elevated serum cystatin C levels (1.6±0.1 mg/L) and decreased eGFR (38.99±12.7 mL/min/1.73 m²) observed in the case group suggest that cystatin C may serve as a potential biomarker for the early diagnosis of left ventricular hypertrophy due to arterial hypertension and chronic kidney disease, as well as for predicting related complications.
3.Effects of some syrups on citric acid induced cough in rat
Munkh-Erdene R ; Davaasambuu V ; Bat-Oyun U ; Ahsholpan B ; Badamtsetseg S ; LKhaasuren R ; Hurelbaatar L
Mongolian Pharmacy and Pharmacology 2023;23(2):20-25
Abstract:
In Mongolia, flu and flu-like diseases affect many people, and pneumonia is a public health concern. Therefore, we have an urgent need to research and develop a new medicinal syrup to replace imported products using raw materials grown in Mongolia and to compare it with similar products. There are imported cough syrup products on the pharmaceutical market of Mongolia, but there are domestic pharmaceutical products. Moreover, there is limited research data on cough relief. The main goal of the research team is to compare the experimentally obtained syrup containing Plantago asiatica L, Malva Sylvestris L. and syrup containing Plantago major L. Juice, honey that produced by Monos Pharm LLC whish the cough relieving drug Gerbion syrup.
Material and methods:
The vivarium of the pharmacology laboratory, Drug research institute,
TPC7062Ti mark IVC system (Shanghai Pretty Industries Co.,Ltd, China) in a special environment
with one care and one feeding regimen (Lab Mice Diet, Constant Formula Balanced Nutrition,
Jiangsu Xietong Pharmaceutical Bio- Engineering Co., LTD, China, www.jsxtsw.com ) used 64
non-WISTAR white rats weighing 180-218 g. Experimental rats were smoked with an aerosol of
17% citric acid aqueous solution for 5 minutes. The statistical processing of the research results
was done using the One-Way ANOVA/Multiple comparisons data of the GraphPad Prism 8 program.
Results and conclusion
Expressing the number of coughs produced in the experimental rats as
a percentage (%), the control group showed 3.95% cough relief, and the experimental group-1 by
48.4%, experimental group-2 by 71.1%, comparison group by 74.6%, respectively has reduced.
Experimental group -2 and comparison group for dry cough caused by citric acid 17%, it affects
the cough receptors in the mucous membrane of the respiratory tract and relaxes the bronchial
muscles (A and C fiber).
Result Analysis
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