Background: Dental caries is a worldwide spreader infectious decease. According to the present studies, the prevalence of the disease is highly dependent on the developmental of the country and its prevention strategies. By the World Dental Federation and World Health Organization (WHO) criteria, dental caries prevalence is increasing every year in Mongolia, which is becoming one of the main problems in our country. According to studies, the most effective method of decreasing prevalence of caries is to have an oral health knowledge, provide caries treatment on early-stage and focusing more on prevention. Aim: The aim of our study was to determine the oral health status among the groups aged between 5, 12, 35-44, 65-74. Materials and Methods: The study has consisted 3512 subjects who selected from 4 age groups (5, 12, 35-44, 65-74) and from 6 districts of Ulaanbaatar city and 5 provinces of Mongolia. The oral examination of each person was done by calibrated dentists according to recommendation of WHO, 2013. The statistical analysis was processed using statistical software system (Stata version 16.0). Result: The prevalence of dental caries and mean of Decayed, Missed, Filled, permanent teeth (DMFt), decayed filled primary teeth were 87.6%, 6.2±0.14 among 5 years old, 77.0%, 2.2±0.03 among 12 years old, 98.1%, 11.8±0.19 among 35-44 years old, 99.8%, 23.6±0.27 among 65-74 years old. The good oral hygiene index was 51.5%, 46.3%, 49.0% and 65.7%. The prevalence of gingivitis was 2.3%, 9.8%, 34.5%, 17.6% and of calculus 0.8%, 7.6%, 62.8%, 31.6%, respectively above groups. The percent of people with removable dentures among 65-74 years old was higher than among 35-44 years old. Conclusion Across multiple age groups, the prevalence and severity of dental caries remain high. Oral hygiene status is predominantly classified as fair to poor. Among adults, partial or complete tooth loss is common; however, the utilization of dental prostheses is low, indicating inadequate prosthetic rehabilitation and limited adaptation to tooth replacement.

Neuromyelitis optica (NMO) is an autoimmune, inflammatory, demyelinating disorder characterised by attacks within the spinal cord and optic nerve. The purpose of this review is to understand the evidence for the effectiveness of plasmapheresis as an add-on therapy for NMO spectrum disorders (NMOSD). The current diagnostic criteria for NMO include optic neuritis, acute myelitis, and at least two of the following three supportive criteria: contiguous spinal cord MRI lesions extending over ≥3 vertebral segments, brain MRI not meeting diagnostic criteria for multiple sclerosis, and NMO-seropositive status.⁵ Myelitis presents with paraparesis and sensory loss below the lesion, sphincter loss, dysaesthesia, and radicular pain.