1.The Relationship Between Metabolic Syndrome and Hyperferritinemia
Ankhbayar B ; Chuluunbileg B ; Amartaivan J ; Nyamdorj D ; Sarantuya E ; Uurtuya Sh
Mongolian Journal of Health Sciences 2025;86(2):30-35
Background:
Hyperferritinemia, characterized by elevated serum ferritin levels, affects approximately 5–25% of the general
population. Given the frequent coexistence of liver iron overload syndrome and metabolic syndrome—both of which
significantly contribute to global morbidity and mortality—it is essential to investigate their interconnections. However,
there is a lack of sufficient evidence, both in Mongolia and internationally, regarding the relationship between iron storage
indicators, metabolic syndrome, and its components. A deeper understanding of iron’s role in disease progression is
needed.
Aim:
This study aims to assess the association between hyperferritinemia and metabolic syndrome parameters.
Materials and Methods:
A cross-sectional analytical observational study was conducted on 159 male participants who
met the inclusion criteria. Data were collected using a standardized questionnaire, and anthropometric measurements
were taken. Blood samples were analyzed to determine glucose, triglyceride, total cholesterol, and high-density lipoprotein
(HDL) levels using an automated biochemical analyzer. Serum ferritin concentrations were measured via the ELISA
method (DRG Instruments GmbH, Germany), with hyperferritinemia defined as a serum ferritin level exceeding 400 ng/
ml. Metabolic syndrome was diagnosed based on the Harmonized criteria. Statistical analyses included the chi-square
test and Fisher’s exact test for categorical variables, the Mann-Whitney U test for non-normally distributed data, and
Spearman’s correlation test to assess relationships between glycemic levels, lipid parameters, and metabolic syndrome
components.
Results:
The findings indicate that 59 participants (37.1%) had metabolic syndrome, while 33 (20.8%) presented with
hyperferritinemia. The presence of metabolic syndrome and hyperglycemia increased the likelihood of developing hyperferritinemia
by 3.4 and 3.7 times, respectively, whereas abdominal obesity raised the risk by 2.2 times.
Conclusion
There was a significant correlation between serum ferritin levels and certain parameters of metabolic syndrome
among the male participants in this study.
2.Comparative Analysis of Outdoor Particulate Matter Concentrations in Ulaanbaatar Using Direct Measurements and Fixed Monitoring Station Data
Maralmaa E ; ; Yerkyebulan M ; Ser-Od Kh ; Shatar Sh ; Gantuya D ; Munkh-Erdene L ; Enkhjargal G ; Myagmarchuluun S ; Gregory Gray ; Junfeng Zhang ; Ulziimaa D ; Damdindorj B ; Davaalkham D ; ; Darambazar G
Mongolian Journal of Health Sciences 2025;89(5):105-111
Background:
Particulate matter with an aerodynamic diameter of 2.5 micrometers or smaller (PM2.5) penetrates
deep into the alveoli through the respiratory tract and is characterized by its ability to induce oxidative stress, systemic
inflammation, and vascular inflammation. Mongolia ranks among the countries with the highest levels of air pollution. In
Ulaanbaatar, where more than half of the country’s population resides, wintertime PM2.5 concentrations often exceed 200
μg/m³, which is about eight times higher than the World Health Organization (WHO) guideline value. A study involving
1,200 adults in Ulaanbaatar showed that quality of life deteriorated sharply during periods of high air pollution, with
effects more pronounced among individuals who already had impaired respiratory function.
Aim:
To examine the relationship between indoor household PM2.5 concentrations and lung function indicators among
adults in Ulaanbaatar and Darkhan.
Materials and Methods:
This analytical cross-sectional study recruited adult participants from Ulaanbaatar and Darkhan
through targeted sampling. Household air quality was measured using PurpleAir sensors, which were installed in
participants’ homes for one month. After exposure measurement, lung function was assessed via spirometry. Statistical
analyses were conducted using SPSS version 25.0.
Results:
A total of 236 participants were included: 114 (48.3%) from Ulaanbaatar and 122 (51.7%) from Darkhan. The
sample consisted of 111 men (47.0%) and 125 women (53.0%). The mean indoor PM2.5 concentration was 66.24 μg/m³
(SD 44.87 μg/m³), ranging from a minimum of 7.79 μg/m³ to a maximum of 264.55 μg/m³. Stratification by housing type
showed the highest PM2.5 levels in gers (82.34 μg/m³), followed by detached houses (67.34 μg/m³), while apartments
had the lowest concentrations (32.24 μg/m³). Correlation analysis revealed statistically significant negative associations
between PM2.5 levels and measures of expiratory function, including the FEV1/FVC ratio, peak expiratory flow (PEF),
and mid-expiratory flow (FEF25–75). Reduced forced vital capacity (FVC) was observed in 9.4% of participants, reduced
forced expiratory volume in one second (FEV1) in 15.3%, and a decreased FEV1/FVC ratio in 3.8%.
Conclusion
Indoor household PM2.5 concentrations were highest in gers, and expiratory flow-related lung function
parameters showed significant negative associations with particulate exposure. This suggests that indoor PM2.5 primarily
affects airflow limitation rather than overall lung volumes in this population.
3.Risk factors for common mental disorders in hospitalized patients during the covid-19 pandemic
Enkhtuvshin R ; Yerkyebulan M ; Munkh-Uchral D ; Enkhnaran T ; Mongoljin A ; Munkh E ; Uranchimeg M ; Maidar E ; Amarsaikhan A ; Amirlan B ; Otgonbayar R ; Nasantsengel L ; Khishigsuren Z
Mongolian Journal of Health Sciences 2025;90(6):32-38
Background:
The COVID-19 pandemic has profoundly impacted mental health, particularly exacerbating conditions
such as depression, anxiety, insomnia, post-traumatic stress disorder (PTSD), and emotional disorders among hospitalized
patients. This study examined the prevalence of COVID-19-related mental health issues and risk factors in hospitalized
patients affiliated with MNUMS, compared to a control group.
Aim:
To assess the prevalence of mental health disorders such as depression, anxiety, insomnia, and post-traumatic stress
disorder (PTSD), and to identify their associated risk factors.
Materials and Methods:
The study was conducted at hospitals under MNUMS, including the Mongolian-Japanese Hospital,
Central Hospital, and the National Center for Maternal and Child Health. A total of 552 participants (399 case
group, 153 control group) who were hospitalized were included. Depression (PHQ-9≥10), anxiety (GAD-7≥10), insomnia
(ISI≥15), and PTSD (PCL-5≥33) were assessed using standardized scales. Analysis was performed using chi-square tests
and binary logistic regression (crude odds ratio [cOR]/adjusted odds ratio [aOR], 95% confidence interval [CI]), adjusted
for group, age, and sex.
Results:
In the case group, depression (23.1% vs. 13.7%, p=0.015, cOR=1.884 [1.124-3.156]), anxiety (16.8% vs. 11.1%,
p=0.096), and any mental disorder (18.0% vs. 13.7%, p=0.225) were higher, while insomnia was lower (19.5% vs. 30.1%,
p=0.008). PTSD was low overall (1.8% vs. 0.7%, p=0.333). Risk factors included female sex (p<0.001, cOR=0.362 for
depression in males), younger age (p=0.004), unemployment (p=0.017), and prior trauma (p<0.001). COVID-19 symptoms
(difficulty breathing) increased the risk of depression (p<0.001, cOR=2.828 [1.708-4.682]).
Conclusion
Hospitalization for COVID-19 increases the risk of depression and anxiety, modulated by demographic,
clinical, and socioeconomic factors. Targeted interventions for vulnerable groups are essential.
4.A study on the effects of elastic and inelastic taping on knee joint kinematics during stair descent
Anuujin E ; ; Munkh-Erdene B ; Batlkham D
Mongolian Journal of Health Sciences 2025;90(6):141-146
Background:
During knee flexion and extension, imbalance in the forces controlling the patella can cause lateral displacement of the patella, resulting in abnormal loading on the femoral groove and leading to anterior knee pain (AKP).
Management of AKP is typically non-surgical. Therefore, the purpose of this study was to investigate the effect of inelastic and elastic taping on knee kinematics during stair descent.
Aim:
To examine the effects of elastic and inelastic taping on knee joint kinematics during stair descent
Materials and Methods:
A total of 60 female participants were recruited. Each participant descended a standardized
20 cm step while being recorded from sagittal and frontal plan using high-speed cameras. Three test conditions were
assessed: no taping, elastic taping, and non-elastic taping. Motion analysis was performed using the “Motion Analysis
Image J” program to measure knee flexion range of motion, knee valgus angle, Q-angle, and pelvic drop
Results:
The mean knee flexion angles were 61.47±5.72 degree (no taping), 61.35±6.33 degree (elastic taping), and
60.21±8.60 degree (inelastic taping), with no significant difference (p=0.305). However, the knee Q-angle differed significantly among conditions: 20.97±11.31 degree (no taping), 20.34±9.10 degree (elastic taping), and 10.16±7.24 degree
(inelastic taping) (p=0.001). Knee valgus angle also showed significant differences (8.14±5.72 degree p=0.001). Pelvic
drop angles were 10.19±6.31 degree (no taping), 9.06±5.31 degree (elastic taping), and 5.17±4.15 (inelastic taping), with
p=0.001, indicating statistical significance.
Conclusion
During stair descent, the use of inelastic taping reduces the knee valgus angle, whereas elastic taping is more
effective in reducing pelvic drop. Both elastic and inelastic taping reduced the knee Q-angle to a similar extent compared
to the no-tape condition; however, neither had an effect on knee flexion range of motion. These findings suggest that inelastic taping is more effective for controlling excessive knee valgus, while elastic taping is more effective for improving
pelvic stability during daily activities.
5.A study on socio-economic condition of health care workers
Nadmidtseren G ; Zoljargalan G ; Yerkebulan M ; Jargalsaikhan T ; Avirmed D ; Unurtsetseg Ch ; Munkh-Uchral D ; Munkhnasan Ts ; Erkhes E ; Baigal D ; Sugarmaa M
Mongolian Medical Sciences 2023;205(4):16-27
Background:
It is stated in the Government Programme of 2016-2020 that public servants, including health care workers, shall be given a gradually increased salary based on their skill, dexterity, workload, and productivity, and such increase started from 2018 as planned. In the health sector of our country, regarding demand and regulation of the programme, the change shall be made that the system for median salary of physicians and overall staff employed at hospitals gets even constructive, and the required human resource for the sector shall be prepared. Thus, inferring from these claims, median salary, real wage, and socioeconomic condition are in critical need for further evaluation.
Objective:
To examine the current socio-economic condition of health care workers, and to study the influencing
factors at play.
Methods:
In this study, we used quantitative and qualitative methods. In the survey, we involved 655 health
care workers from 6 family health centers, 2 district hospitals, 3 health centers (district-based) in
Songinokhairkhan, Sukhbaatar, and Baganuur districts; and Provincial hospital, regional diagnosis and
health center, 16 soum health centers from Khovd, Uvs, Arkhangai, Bulgan, Khentii, Dornod, Umnugovi, and Dornogovi provinces, along with 3 National specialized health centers and 1 National central hospital. As for data gathering for the qualitative analysis, 30 focus group interviews and 47 key informant interviews were conducted for the purpose of examining socioeconomic condition, real wage sufficiency of health care workers.
Results:
Average household income of study participants was 1,880,269 tugrik, the real wage was 1,073,065
tugrik, and the overall household is seen to be composed of 2 different sources on average, namely,
self-wage and the income coming from family members or supplement of Child Money Programme. It
has come to notice that 19.5% of the participants have lower than average living standard, 89.2% have
2 different loans (mortgage, auto loan or mobile application based loans). Material deprivation index is
seen to be 2.73, hence deemed as insufficient. In order to increase the real wage of those workers, it
shall be taken into consideration that the basic salary is low, and some financial supplements need to
be given. Furthermore, the performance based funding system of health sector is seen to be in need of
improvement.
Conclusion
Real wage of the health care workers is, thus, insufficient. The fact that one in every five workers in this sector have lower than average living standard, and the material deprivation index is 2.73 implying that the financial lives of health care workers are immensely fragile.
6.The result of the changes of the work-related stress of physicians and nurses with the critical ill patient units
Bazarragchaa S ; Munkh-Erdene L ; Khishigsuren Z ; Delgermaa E ; TSeden P
Mongolian Pharmacy and Pharmacology 2019;15(2):7-11
Background:
The career and work of medical workers are considered to be the occupation of
the highly responsible job of the worldwide.
Goal:
To identify the percentage of the work-related stress, the burnout, and the symptoms of
work-related stress of the physicians and nurses who is working at the critical and intensive care
units of UB hospitals.
Materials and methodology:
The survey was done by quantitative methods and cross sectional design. The study data was collected using the validated questionnaire for the work related stress. The results of the study were analyzed by the Microsoft Excel and SPSS 20 program.
Results
The response rate was 97.3% The study found that 78.7% of respondents reported having regular stress; and 89.4% of all participants in the survey had a personal burnout, 90.4% had work-related burnout and 94.5% had a high level of client-related burnout.
Physical symptoms include the insomnia 76.7%; psychological symptoms - the headaches 65%; behavioral symptoms as like forgetfulness and annoyance 53.3%; cognitive symptoms as like an increase in sick days or absenteeism by 40% for all physicians and nurses.
7.Identification of Enteroaggregative Escherichia coli in Mongolia
Munkhdelger Ya ; Undramaa G ; Munkh-Od Ts ; Nyamaa G ; Tsatsral E ; Sarantuya J
Mongolian Medical Sciences 2015;172(2):22-27
Introduction: Enteroaggregative Escherichia coli (EAEC) is an important agent of acute and
persistent diarrhea worldwide. Few cases have been reported in healthy children. EAEC strains are
characterized by aggregative adherence (AA) to HEp-2 cells, wherein bacteria are seen in “stacked
brick” aggregates attaching to HEp-2 cells and usually to the glass surface between cells.
Goal: To identify Enteroaggregative Escherihia coli using multiplex polymerase chain reaction (PCR)
and HEp-2 adherence assay in Ulaanbaatar, Mongolia
Materials and Methods:
A total of 329 E. coli strains were isolated from stool with diarrhea in National Center for Communicable
Diseases from July 2012 through September 2014. All specimens were processed by routine
microbiological and biochemical tests in the bacteriological laboratories to identify Salmonella spp.,
Shigella spp. All specimens in our study were negative for these bacterial and parasitic pathogens.
The biofilm formation was evaluated by the growth rate of E.coli on plastic surface. PCR assays
were used to detect genes of five types of diarrheagenic E.coli (DEC). All of the DEC strains showed
mannose-resistant adherence to HEp-2 cells, and aggregative adherence was predominant in these
isolates. Bacterial susceptibility to antimicrobial agents determined by the Kirby Bauer disk diffusion
method on Muller Hinton agar.
Results:
EAEC (31.9%) was the most prevalent by PCR and HEp-2 assay comparing with others. EAEC by
multiplex PCR in samples (11, 3.3%), followed by enteropathogenic E.coli (EPEC) seen in 2.1%.
Enterohemorrhagic E.coli (EHEC) and enteroinvasive E.coli (EIEC) were found in 7 (2.1%) and 1
(0.3%) of the samples. Enterotoxigenic E.coli (ETEC) and diffusely adhering E.coli were detected
in 2 (0.6%), respectively. The evaluation of bacterial biofilm formation using 96 well plates showed
309 negative (93%), 15 weak biofilm (4.6%) and 8 moderate biofilm (2.4%) formation for E.coli and
no strong biofilm forming strain was detected. Above 50% of antibiotic resistance was observed
for ampicillin, trimethoprim/sulfamethoxazole, cefuroxime and cephalotin. Also, 95.4% of isolates
were resistant to at least three different classes of antimicrobial agents and considered as multidrug
resistance.
Conclusion:
EAEC is most prevalent pathogen among DEC in our samples. It is necessary to implement EAEC
identifying method on Hep-2 assay in our laboratory practice.
8. DETECTING FOR WORK BURNOUT SYNDROME AMONG WORKERS OF NCMH, USING MBI SCALE
Odonchimeg D ; Khishigsuren Z ; Khongorzul D ; Munkh E ; Bayarmaa B ; Enkhtaivan B ; Baatarjav O ; Tsendsuren Z ; Selenge E
Innovation 2015;9(1):20-23
Mental health team includes a psychiatrist, a psychiatric nurse, psychologist and social workers. Mental health workers are more stressful than other sector’s workers. Mental workers are working with mental patients, who have chronic,severe and poor prognosis disorders for long time, and may have Work Burnout Syndrome (WBS). Worldwide, many researches are used Maslach Burnout Inventory (MBI) for assessing WBS. Our goal was to detect risk factors of WBS among mental health workers. We conducted the survey among workers mental (doctors, nurses and assistant nurses) and study design was a descriptive cross-sectional. We are used a questionnaire, is including MBI. Our subjects were 103 workers, who were 27 (26,2%) doctors, 32 (31,1%) nursesand 44 (42,75) nurse- assistant. They were 15 (14,6%) male and 88 (85,4%) female and average age was 38.21 (SD = 8.92). The worker’s average professional working year was 13.09 (SD = 9.76). Most of subjects (n=63 61.2%) were shift-workers and they (n=99 96.1%) have high workload. We determined 3 groups by level of MBS among mental workers, such as the group with EE’s high scale (n = 27; 27%), thegroup with DP’s high scale (n = 23; 22.8%) and the group with PA’s high scale (n = 50; 50.5%).MBS was high among NMHC’s workers. However their work time is low, but theyhave risk factors for MBI such as high workloads, shift work, number of patients. Workers of emergency department had termination burnout syndrome more than other acute departments. This was associated with working condition.
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