Background: A drug related problem is defined by the Pharmaceutical Care Network Europe Association as an an event or circumstance involving drug therapy that actually or potentially interferes with desired health outcomes. One critical aspect of preventing such errors is proper dose adjustment, which plays a vital role in the diagnosis and treatment of disease. For instance, adjusting the dose of warfarin based on the patient’s INR level is essential. In a 1995 study conducted in England, clinical pharmacists recommended target doses of angiotensin-converting enzyme (ACE) inhibitors for patients with chronic heart failure. As a result, patients experienced a significant reduction in pulmonary and peripheral edema, along with improved exercise test outcomes. At the Mongolian-Japanese Hospital of the Mongolian Medical University of Science and Technology, it is important to analyze dosage-related issues identified by clinical pharmacists and inform healthcare professionals about common dosage selection errors and associated risks. Aim: We analyzed issues related to medication dosage. Materials and Methods: A retrospective study was conducted to examine problem related to dosage detected through prescription monitoring at the Mongolian Japanese Hospital of the Mongolian National University of Health Sciences from 2023 to 2024. Results: Out of a total of 2340 drug-related problem identified across five inpatient wards during this period, 581 (100%) were related to dosage. Clinical pharmacists performed prescription review on approximately 67% of all inpatients, which was consistent between years. However, medication-related problems tended to decrease from 41.1% (n=1499) in 2023 to 22.3% (n=841) in 2024 (p=0.05). The majority of dose-related problems, 75.6% (n=440), were overdoses. Medication-related problems were most common in the surgical department, with 59.5% (n=346) (p=0.001). The most frequent dosage-related errors involved exceeding the daily dose of diclofenac, administering higher- than-recommended doses of ceftriaxone, failing to adjust cefotaxime for renal function, and using inappropriate doses of metronidazole in patients with impaired liver function. The leading cause of these errors was failure to adhere to guideline-recommended dosing, which accounted for 71.3% (n=415) of cases (p=0.001). When dosage-related recommendations were provided to physicians before of treatment, acceptance rates increased by 14% (p=0.001). These interventions resulted in an estimated cost saving of 1.267.219₮ and a reduction of 363 injections. Conclusion Therefore, clinical pharmacist-led prescription review can help reduce the risk of dosage errors, lower associated healthcare costs, and alleviate the burden on medical staff.

Introduction : Noncommunicable diseases (NCDs) caused at least 43 million deaths in 2021, equivalent to 75% of non-pandemic-related deaths globally. Cardiovascular diseases account for most NCD deaths, or at least 19 million deaths in 2021, followed by cancers (10 million), chronic respiratory diseases (4 million), and diabetes (over 2 million including kidney disease deaths caused by diabetes). These four groups of diseases account for 80% of all premature NCD deaths. According to the Fourth National Survey on the Prevalence of Noncommunicable Diseases, Injuries, and Their Risk Factors: 14.0% of adults aged 15–69 have experienced a heart attack or stroke, 11.0% report taking aspirin to prevent or manage cardiovascular disease (CVD), 2.2% use lipid-lowering medications (statins) for CVD prevention or treatment, among adults aged 40–69, 19.3% are at high risk of developing CVD within the next 10 years. These findings underscore the urgent need to strengthen cardiovascular disease prevention efforts and improve the management of key risk factors in Mongolia. Goal: To determine the population’s knowledge, attitudes, and practices related to cardiovascular disease risk factors and healthy lifestyle behaviors. Materials and Methods: This descriptive cross-sectional study included 2,532 participants aged 18–69 years from all 21 provinces of Mongolia and Ulaanbaatar city, as part of the “Cardiology, Cardiac Surgery, and Telemedicine in Mongolia” (MON/007) Project. Data were collected using a structured questionnaire comprising six sub-sections, designed to assess knowledge, attitudes, and practices related to 10 modifiable cardiovascular risk factors. Ethical approval was obtained prior to the study, and data were analyzed using SPSS version 23. Results: Thirty-three percent of study participants reported having no knowledge of cardiovascular disease, indicating that roughly one in three adults consider themselves to have little or no understanding of cardiovascular health. In the study, 53.0% of participants reported being unaware of the symptoms of a heart attack, while 42.0% did not recognize the symptoms of a stroke. Among participants who could identify these symptoms, 68.0% indicated dizziness as a sign of hypertension, 65.0% reported headache, and 58.0% noted blurred vision. Among the respondents, 31.0% knew that the normal arterial blood pressure for an adult is 120/80 mmHg, 57.0% were aware that an adult should sleep 7–8 hours per day, 13.0% knew about body mass index (BMI), 30.0% were aware of fasting blood glucose levels, and 44.0% recognized that adults should engage in 30 minutes of physical activity daily. Knowledge of key physiological indicators was significantly associated with educational attainment, gender, and age group, with lower levels of awareness observed among participants with lower education, males, and younger adults (p=0.001). The majority of participants (75.0%-96.0%) reported being aware of the modifiable risk factors for cardiovascular disease. Among the study participants, nine out of ten agreed that maintaining a healthy lifestyle includes regular physical activity, exercising, walking short distances, and understanding that hypertension is harmful and smoking adversely affects the heart. Furthermore, 80–85% reported avoiding excessive alcohol consumption, and 79% believed that cardiovascular disease is preventable. To prevent or reduce obesity, a risk factor for cardiovascular disease, 49.0% of participants reported engaging in regular physical activity, while 33.0% reported following a healthy diet. Among all study participants, 61.0% had never checked their cholesterol levels, 49.0% had never measured their blood glucose, and 15.0% had never monitored their blood pressure. Among respondents exhibiting 1–3 common risk factors, the majority were female, aged 25–34 years, living in rural areas or ger districts, with secondary or specialized secondary education, employed in government institutions, and had a normal BMI. In contrast, among those with 7 or more common risk factors, the majority were male, aged 35–44 years, residing in Ulaanbaatar, living in ger districts, and employed in private organizations. Conclusion Most of surveyed participants had sufficient knowledge and positive attitudes toward modifiable risk factors for cardiovascular diseases (p=0.001). However, they exhibited inadequate preventive practices related to these risk factors. This indicates the importance of targeted intervention on behavior change to address this gap.

Background: Numerous studies among the western population have been demonstrated that the intolerance of uncertainty can cause mental disorders such as OCD, anxiety disorder major depressive disorder. The lack of research in this field among the eastern population, especially the Mongolians, is the basis of our study. Material and Methods The study was designed as a cross-sectional study with a self-report questionnaire and conducted between December 5th and February 5th of 2022. The Intolerance of Uncertainty scale (IUS-12) is for measuring intolerance of uncertainty, Patient health questionnaire (PHQ-9), and Generalized anxiety disorder (GAD-7) were used to measuring mental health among study participants. The present study was undertaken following ethical approval from the MNUMS scientific research ethics committee (approval number: 2021/3-06). Statistical analysis was performed using SPSS version 24. Purpose: The current study was aimed to explore the impact of intolerance of uncertainty on students’ mental health. Results: Total of 3137 students (2440 Chinese, 697 Mongolian), 65.7% of them were female students participated in the current study. The mean score of IUS-12 was 33.53±7.72 among Chinese students, while 38.65±8.48 among Mongolians. This reveals the statistically significant (p=0.003) difference intolerance level between Chinese and Mongolian students. Moreover, Chinese students were less depressed and less anxious than Mongolian students. The anxiety and depression level was directly impacted by the influence of intolerance of uncertainty. Conclusion Chinese students are more tolerant toward uncertainties than Mongolian students. The intolerance of uncertainty causes depression and anxiety, regardless of nationality.