1.Prostatic Artery Embolisation for Refractory Haematuria in Advanced Prostate Cancer: A Case Report of PSA Normalisation
Mogaraj Sellapan ; Mohammad Hifzi Mohd Hashim ; Lim Li Yi ; Zulkifli Md Zainuddin
Journal of Surgical Academia 2025;15(2):45-48
Prostatic Artery Embolisation for Refractory Haematuria in Advanced Prostate Cancer: A Case Report of PSA Normalisation
Prostatic artery embolisation (PAE) is a well-established minimally invasive procedure for the management of lower urinary tract symptoms secondary to benign prostatic hyperplasia. In patients with advanced prostate cancer, its primary role has been palliative, particularly for controlling refractory haematuria. However, emerging evidence suggests that PAE may offer additional cytoreductive benefits. We presented the case of an 85-year-old male with advanced prostate cancer and multiple comorbidities, including severe aortic stenosis and stage 4 chronic kidney disease, who developed refractory gross haematuria unresponsive to conservative management. Due to high surgical risk, bilateral PAE was performed via a single right femoral artery access. The procedure resulted in complete resolution of haematuria, allowing early catheter removal. Remarkably, his prostate-specific antigen (PSA) declined from 5.28 ng/mL to 0.45 ng/mL over seven months, in the absence of systemic therapy. The patient remained haematuria-free with improved voiding symptoms. This case highlights the effectiveness of PAE for haemostatic control in advanced prostate cancer and suggests potential cytoreductive effects, evidenced by sustained PSA normalisation. PAE may serve a dual role in symptom control and disease modulation in patients unsuitable for surgery or systemic therapy. Further studies are warranted to explore its oncologic impact.
2.Rare Occurrence of Paratesticular Rhabdomyosarcoma in Adulthood: A Case Report
Mohammad Hifzi Mohd Hashim ; Zulkifli Md Zainuddin ; Khoo Hau Chun ; Li Yi Lim ; Gilbert Peh Voon Yeow
Journal of Surgical Academia 2024;14(2):31-35
Rare Occurrence of Paratesticular Rhabdomyosarcoma in Adulthood: A Case Report
Paratesticular rhabdomyosarcoma is an extremely rare malignant tumour that primarily affects pediatric patients but is uncommon in adults. Prompt diagnosis and treatment are essential to prevent metastasis and improve prognosis. A 28-year-old male was presented with a painless right scrotal swelling. Physical examination revealed a palpable mass in the right scrotal region, raising suspicion of a malignant tumour. Ultrasonography showed a hypoechoic mass originating from the right epididymis. The patient underwent a high inguinal orchidectomy, and histopathological examination confirmed the diagnosis of paratesticular rhabdomyosarcoma. Staging computed tomography revealed no evidence of metastasis. The patient received chemotherapy based on risk stratification. Paratesticular rhabdomyosarcoma carries a poor prognosis in advanced stages, highlighting the importance of early diagnosis. Surgery remains the mainstay of treatment and the role of adjuvant therapy in adults is not well established. Understanding the clinical manifestations, diagnosis and treatment of this rare malignancy can aid in improved management and outcomes

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