Facial Anthropometry and Aesthetic Preferences in Malay Women: A Comparative Study The study aimed to explore the relationship between Malay females’ facial attractiveness with golden ratio, neoclassical canons, “ideal” ratios and “ideal” angles; and to compare self-perceived facial attractiveness and health-related quality of life (HRQoL) among Malay females with different skeletal patterns. Sixty-four young Malay female participants each completed a set of self-administered questionnaires and have five facial photographs taken. The self-assessed satisfaction with facial appearance and HRQoL were compared between participants with different dentoskeletal patterns. Seventy-seven facial anthropometry parameters related to the golden ratio, neoclassical canons, ideal ratios and ideal angles were measured. Subsequently, 15 sets of photographs representing different skeletal patterns were randomly selected. A panel of juries evaluated facial attractiveness using a 7-point Likert scale. The correlation between facial attractiveness and measured parameters was studied. Results indicated that mean rank FACE-Q Rasch scores of participants’ self-rated satisfaction on their facial appearance and HRQoL were not significantly different statistically (p = 0.06–0.81) between Class I, II and III. One hundred and eighty juries (mean 24.33±3.82 years old) were recruited. No statistically significant correlations found between facial attractiveness rated by juries and measured parameters related to the golden ratio (r = –0.47 to 0.36; p = 0.08 to 0.98), neoclassical canons (r = –0.27 to 0.43; p = 0.11 to 0.96), ideal ratios (r = –0.32 to 0.47; p = 0.08 to 0.96) and ideal angles (r = –0.23 to 0.28; p = 0.31 to 0.92). In conclusion, the study found that the golden ratio, neoclassical canons, ideal ratios, and ideal angles were not found to be correlated with the facial attractiveness of Malay females. Therefore, these guidelines should be used with discretion during treatment planning and outcome assessment for this specific ethnic group.