1.Application value of photon-counting detector CT in preoperative assessment of pancreatic cancer
Jingyi LIU ; Liang ZHU ; Chen LIN ; Jiashu HAN ; Chao ZHANG ; Yun WANG ; Mengzhe LYU ; Xi ZHAO ; Weibin WANG ; Feng FENG
Chinese Journal of Radiology 2025;59(12):1369-1376
Objective:To investigate the application value of photon-counting detector CT (PCD-CT) in preoperative identification of critical anatomical structures and surgical assessment in pancreatic cancer, and to compare its performance with conventional energy-integrating detector CT (EID-CT) in delineating tumor margins, vascular structures, and neural anatomy.Methods:This single-center retrospective matched case-control study included 25 patients with pathologically confirmed pancreatic ductal adenocarcinoma who underwent PCD-CT enhanced scanning and curative surgery at Peking Union Medical College Hospital between February and June 2025 (PCD-CT group). These patients were matched in a 1∶2 ratio to 50 patients who underwent EID-CT between January 2016 and December 2024 and subsequently received curative surgery (EID-CT group). Tumor boundary clarity, vascular visualization scores, and neural structure visibility were subjectively evaluated using the Likert scoring system. The assessed vessels included the celiac artery, common hepatic artery, superior mesenteric artery, splenic artery, portal vein, superior mesenteric vein, splenic vein, and pancreaticoduodenal arterial arcade. Imaging-based assessment of structural involvement was compared with intraoperative findings and pathological results to calculate diagnostic accuracy. Surgeons rated the usefulness of PCD-CT images for identifying key structures and determining resectability using a 5-point Likert scale. The Mann-Whitney U test was used for group comparisons of subjective scores, and categorical data were analyzed using the χ2 test or Fisher exact test. Results:The PCD-CT group showed significantly higher scores for tumor boundary clarity, vascular visualization, and neural structure detectability than those of the EID-CT group (all P<0.05). The accuracy of assessing superior mesenteric vein involvement was 96.0% (24/25) in the PCD-CT group and 72.0% (36/50) in the EID-CT group, with a significant difference ( χ2=6.00, P=0.014). Postoperative surgeon evaluations indicated that PCD-CT provided substantial assistance for both key structure identification [5 (5, 5)] and resectability assessment [5 (4, 5)]. Conclusion:PCD-CT demonstrates superior performance over EID-CT in preoperative delineation of tumor margins, vascular structures, and neural anatomy and in the assessment of structural involvement in pancreatic cancer. It provides valuable anatomical information to support preoperative evaluation and surgical decision-making.
2.Application value of photon-counting detector CT in preoperative assessment of pancreatic cancer
Jingyi LIU ; Liang ZHU ; Chen LIN ; Jiashu HAN ; Chao ZHANG ; Yun WANG ; Mengzhe LYU ; Xi ZHAO ; Weibin WANG ; Feng FENG
Chinese Journal of Radiology 2025;59(12):1369-1376
Objective:To investigate the application value of photon-counting detector CT (PCD-CT) in preoperative identification of critical anatomical structures and surgical assessment in pancreatic cancer, and to compare its performance with conventional energy-integrating detector CT (EID-CT) in delineating tumor margins, vascular structures, and neural anatomy.Methods:This single-center retrospective matched case-control study included 25 patients with pathologically confirmed pancreatic ductal adenocarcinoma who underwent PCD-CT enhanced scanning and curative surgery at Peking Union Medical College Hospital between February and June 2025 (PCD-CT group). These patients were matched in a 1∶2 ratio to 50 patients who underwent EID-CT between January 2016 and December 2024 and subsequently received curative surgery (EID-CT group). Tumor boundary clarity, vascular visualization scores, and neural structure visibility were subjectively evaluated using the Likert scoring system. The assessed vessels included the celiac artery, common hepatic artery, superior mesenteric artery, splenic artery, portal vein, superior mesenteric vein, splenic vein, and pancreaticoduodenal arterial arcade. Imaging-based assessment of structural involvement was compared with intraoperative findings and pathological results to calculate diagnostic accuracy. Surgeons rated the usefulness of PCD-CT images for identifying key structures and determining resectability using a 5-point Likert scale. The Mann-Whitney U test was used for group comparisons of subjective scores, and categorical data were analyzed using the χ2 test or Fisher exact test. Results:The PCD-CT group showed significantly higher scores for tumor boundary clarity, vascular visualization, and neural structure detectability than those of the EID-CT group (all P<0.05). The accuracy of assessing superior mesenteric vein involvement was 96.0% (24/25) in the PCD-CT group and 72.0% (36/50) in the EID-CT group, with a significant difference ( χ2=6.00, P=0.014). Postoperative surgeon evaluations indicated that PCD-CT provided substantial assistance for both key structure identification [5 (5, 5)] and resectability assessment [5 (4, 5)]. Conclusion:PCD-CT demonstrates superior performance over EID-CT in preoperative delineation of tumor margins, vascular structures, and neural anatomy and in the assessment of structural involvement in pancreatic cancer. It provides valuable anatomical information to support preoperative evaluation and surgical decision-making.
3.The Definition of Complex Trauma in Psychological Medicine (review)
Jing SHAN ; Dengfeng CHEN ; Mengzhe FENG
Chinese Journal of Rehabilitation Theory and Practice 2013;19(2):148-150
Identification of complex traumatic stress disorders has beyond the traditional definition of trauma and experimentally diagnostic statement of post-traumatic stress disorder (PTSD) in Diagnostic and Statistical Manual of Mental Disorders (DSM-Ⅳ-TR). Because of the disturbance of complex trauma, traumatic stress symptoms and its hurt results, it is difficult to make accurate diagnosis and effective treatment. This article began with the reasons why it was hard to define complex trauma, viewed from clinical diagnosis and treatment, discussed the importance of defining complex trauma, its multiple effects on individuals and the psychological and social factors aggravating complex trauma.
4.Eye Movement Desensitization and Reprocessing Integrating with Ego State Therapy for Clients with Trauma Disorders (review)
Jing SHAN ; Bao TIAN ; Mengzhe FENG
Chinese Journal of Rehabilitation Theory and Practice 2011;17(3):250-252
Post-traumatic stress disorder (PTSD) has long been clinical practice to use a three-part phased model in the treatment of trauma and the dissociative disorders. The phased treatment is an intrinsic element of the model presented throughout this article, which integrates the eye movement desensitization and reprocessing (EMDR) standard protocol and additional components: ego state therapy, attachment theory, and dissociative disorder treatment interventions. Although the researches on this model are still in its infancy, it is the current standard of care because of its efficacy with traumatized and dissociative-disordered clients.
5.Advance in Diagnosis of Post-traumatic Stress Disorder following Intellectual Disability(review)
Jing SHAN ; Mengzhe FENG ; Bao TIAN
Chinese Journal of Rehabilitation Theory and Practice 2010;16(8):760-763
Post-traumatic stress disorder (PTSD) is the most serious post-disaster physical and mental barrier, and intellectual disabilities are more sensitive to the negative effects caused by trauma than the healthy population. The debate existing extensively makes the diagnosis of PTSD in patients with intellectual disability difficult to be understood. There is a need to use uniform diagnostic criteria, howere, it still remains a problem for less experienced clinicians.


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