OBJECTIVE: To explore the effect and mechanism of kidney-warming and astringent therapy in treating nephrotic syndrome patients with deficiency of spleen and kidney yang and overflow of water, and to observe the change of plasma endothelin and interleukin-2 receptor after treatment. METHODS: Forty-four patients were randomly divided into conventional steroid treated group (control group, 20 cases) and conventional steroid plus kidney-warming and astringent therapy treated group (treatment group, 24 cases). The levels of plasma endothelin (ET) and soluble interleukin-2 receptor (sIL-2) were observed. RESULTS: Before treatment, plasma ET and sIL-2 in the patients were significantly higher than those in healthy people (P<0.01). After treatment, the ET and sIL-2 levels were obviously improved in both treated groups (P<0.05) and the improvement in the treatment group was more obvious. The difference between the two treated groups after treatment was significant (P<0.05). CONCLUSION: Conventional treatment plus kidney-warming and astringent therapy can effectively improve the levels of plasma ET and sIL-2 in treating nephrotic syndrome patients with deficiency of spleen and kidney yang and overflow of water, and hence alleviate the damage of renal tissue.

Objective To evaluate the analgesic effects of continuous infusion of morphine into epidural space(CIEA) on postoperative pain relief after prostatectomy. Methods 40 cases of benign prostate hypertrophy were selected and randomly divided into two groups,experimental group(CIEA),0 2mg/h of morphin was injected into epidural space,control group(MI),50mg of pethidine was injected whenever patient feel pain.VAS(Vision simulate score),frequency and duration of bladder spasm,discontinuance time of bladder irrigation,HR BP and RR,were observed. Results The experimental group was superior to the control group with characteristics of stable analgesic effect,short duration and low frequency of bladder spasm(P