Objective:To explore the job preference and willingness to pay of resident training physicians in Chengdu, China.Methods:The questionnaire was designed by means of the discrete choice experiment. The questionnaire contains the basic information of the survey object and the discrete choice set (including workplace, working intensity, monthly salary, staffing of public institution, and career development, each with several levels). A total of 116 resident training physicians recruited by three standardized residents training centers in Chengdu were selected to conduct the questionnaire survey, and grouped based on their identity and major. The mixed logit model was used to analyze job preferences and willingness to pay of resident training physicians.Results:Except for career development, other four attributes had statistically significant effects on job selection of resident training physicians ( P<0.05), of which working intensity was the most influential attribute, with the highest willingness to pay. The subgroup analysis results showed that staffing of public institution was concerned by clinical postgraduates and resident training physicians in non-scarce majors. Conclusions:Economic and non-economic factors both affect the job preferences of resident training physicians, while working intensity is the most important factor. Resident training policy should focus on adjusting the scale and type of resident physician enrollment, and strengthen humanistic care and career education of resident training physicians.

Objective:To explore the job preference and willingness to pay of resident training physicians in Chengdu, China.Methods:The questionnaire was designed by means of the discrete choice experiment. The questionnaire contains the basic information of the survey object and the discrete choice set (including workplace, working intensity, monthly salary, staffing of public institution, and career development, each with several levels). A total of 116 resident training physicians recruited by three standardized residents training centers in Chengdu were selected to conduct the questionnaire survey, and grouped based on their identity and major. The mixed logit model was used to analyze job preferences and willingness to pay of resident training physicians.Results:Except for career development, other four attributes had statistically significant effects on job selection of resident training physicians ( P<0.05), of which working intensity was the most influential attribute, with the highest willingness to pay. The subgroup analysis results showed that staffing of public institution was concerned by clinical postgraduates and resident training physicians in non-scarce majors. Conclusions:Economic and non-economic factors both affect the job preferences of resident training physicians, while working intensity is the most important factor. Resident training policy should focus on adjusting the scale and type of resident physician enrollment, and strengthen humanistic care and career education of resident training physicians.

Objective:To investigate the effect of water intake on bladder filling time before embryo transfer.Methods:A total of 189 patients were collected from February to June 2023 who were to undergo embryo transfer in Guangdong Women and Children Hospital. The patients were divided into group A ( n=61), group B ( n=64) and group C ( n=64) using a random number table and they were respectively given 300 mL, 500 mL and 700 mL water to drink. Abdominal ultrasound was performed every 15 min, a total of 1-5 times, from 45 min after drinking water until the bladder filling. The bladder filling time and bladder volume were collected. Kaplan-Meier method was used to compare the difference of bladder filling time among the three groups. The multivariate Cox regression was used to analyze factors of bladder filling time. Results:The cumulative bladder filling rates of group A, group B and group C at 105 min after drinking water were 57.4% (35/61), 90.6% (58/64) and 98.4% (63/64), respectively, and the median survival time (95% CI) of bladder filling was 105.0 (89.9-120.1) min, 60.0 (55.4-64.7) min and 60.0 (55.4-64.6) min, respectively. Pairwise comparison of Kaplan-Meier analysis revealed that the bladder filling time of group A was longer than that of group B and group C ( P<0.001), and there was no statistically significant difference between group B and group C ( P>0.05). The results of age-stratification analysis showed that the bladder filling time of younger patients in group A [90.0 (75.2-104.8) min] was longer than that in group B [60.0 (55.8-64.2) min, P<0.001] and group C [60.0 (55.1-64.8) min, P<0.001], and there was no statistical significance between group B and group C ( P>0.05); the bladder filling time of older patients in group C [60.0 (59.1-70.9) min] was shorter than that in group A [105.0 (89.9-120.1) min, P<0.001] and group B [75.0 (64.3-85.7) min, P=0.027], there was no statistical significance between group A and group B ( P>0.05). Multivariate Cox regression analysis showed that taking group A as reference, the hazard ratio ( HR, 95% CI) of groups B and C were 2.71 (1.78-4.21) and 3.23 (2.10-4.96), both P<0.001. The HR (95% CI) of the elderly patients was 0.69 (0.49-0.99), P=0.044. Conclusion:Water intake and age are independent factors affecting bladder filling time in embryo transfer patients. Patients are recommended to drink 500 mL of water 75 min before embryo transfer and appropriately increase the amount of water or extend the bladder preparation time after drinking water for elderly patients.

Objective:To investigate the effect of water intake on bladder filling time before embryo transfer.Methods:A total of 189 patients were collected from February to June 2023 who were to undergo embryo transfer in Guangdong Women and Children Hospital. The patients were divided into group A ( n=61), group B ( n=64) and group C ( n=64) using a random number table and they were respectively given 300 mL, 500 mL and 700 mL water to drink. Abdominal ultrasound was performed every 15 min, a total of 1-5 times, from 45 min after drinking water until the bladder filling. The bladder filling time and bladder volume were collected. Kaplan-Meier method was used to compare the difference of bladder filling time among the three groups. The multivariate Cox regression was used to analyze factors of bladder filling time. Results:The cumulative bladder filling rates of group A, group B and group C at 105 min after drinking water were 57.4% (35/61), 90.6% (58/64) and 98.4% (63/64), respectively, and the median survival time (95% CI) of bladder filling was 105.0 (89.9-120.1) min, 60.0 (55.4-64.7) min and 60.0 (55.4-64.6) min, respectively. Pairwise comparison of Kaplan-Meier analysis revealed that the bladder filling time of group A was longer than that of group B and group C ( P<0.001), and there was no statistically significant difference between group B and group C ( P>0.05). The results of age-stratification analysis showed that the bladder filling time of younger patients in group A [90.0 (75.2-104.8) min] was longer than that in group B [60.0 (55.8-64.2) min, P<0.001] and group C [60.0 (55.1-64.8) min, P<0.001], and there was no statistical significance between group B and group C ( P>0.05); the bladder filling time of older patients in group C [60.0 (59.1-70.9) min] was shorter than that in group A [105.0 (89.9-120.1) min, P<0.001] and group B [75.0 (64.3-85.7) min, P=0.027], there was no statistical significance between group A and group B ( P>0.05). Multivariate Cox regression analysis showed that taking group A as reference, the hazard ratio ( HR, 95% CI) of groups B and C were 2.71 (1.78-4.21) and 3.23 (2.10-4.96), both P<0.001. The HR (95% CI) of the elderly patients was 0.69 (0.49-0.99), P=0.044. Conclusion:Water intake and age are independent factors affecting bladder filling time in embryo transfer patients. Patients are recommended to drink 500 mL of water 75 min before embryo transfer and appropriately increase the amount of water or extend the bladder preparation time after drinking water for elderly patients.

OBJECTIVE:To observe the stability of phacolin eye drops.METHODS:The content and the stability of phacolin eye drops were determined by ultraviolet spectrophotometry and the initial average rate method respectively.RESULTS:The activation energy for pyrolytic reaction of phcolin eye drops was25.681kcal/mol,the shelflife of phacolin eye drops at room temperature(25℃)and10℃were88and878days respectively.CONCLUSION:The determination of the stability of phacolin eye drops with initial average rate method is useful and simple.