1.A comparison of curriculum design for undergraduate education of rehabilitation therapy in mainland China and Taiwan area
Yuanwen LIU ; Cuihuan PAN ; Rui YU ; Ping MIAO ; Nan HU ; Maohua FAN ; Zhen FU ; Changlin XIAO
Chinese Journal of Medical Education Research 2018;17(3):310-315
Undergraduate education started late in rehabilitation medicine in mainland China.At present,there are some shortcomings in current undergraduate education for rehabilitation medicine in mainland China,mainly due to the shortage of teachers,the poor pertinence of professional subjects,the broad and superficial knowledge,and the lack of close connection with the necessary professional knowledge of rehabilitation technologies.The Department of Rehabilitation in Taiwan starts its undergraduate education earlier.The curriculum has been sub-professionally oriented.Its subjects are highly targeted and detailed in content.At the same time,it emphasizes forward-looking education such as "statistics".In view of this,the mainland colleges and universities should standardize the undergraduate education of rehabilitation therapies,strengthen the training of professional teachers,pay attention to the cross-mutualism of theory and practice in the teaching plan,enrich the number of professional courses,the appropriate introduction of teaching methods of scientific research,standardize the teaching management system.
2.Effects of perioperative rehabilitation for patients with self-forearm internal arteriovenous fistula
Maohua CHENG ; Yu ZHANG ; Sufen YAN ; Ni HU
Chinese Journal of Practical Nursing 2015;31(15):1138-1140
Objective To evaluate the effects of perioperative rehabilitation for patients with self-forearm internal arteriovenous fistula.Methods Divided 124 patients with end-stage renal disease into the functional training group (65 cases,A group)and the control group(59 cases,B group) randomly,and then compared certain related indexes between the two groups.Results In the A group,the artery diametcr was obvious widen before functional training without operation,and the vein diameter was obvious widen before functional training without operation too,P < 0.05.After operation,the A group Anastomotic unobstructed was obviously better than B group in one-stage,P < 0.05.A group with thrombosis cases significantly less postoperative than B group,P < 0.05.A group with edema of hands was significantly shorter than B group,P < 0.01.Postoperative fistula time to maturity in the A group was (43.76 ± 2.21) days,which was significantly shorter than that of in the B group,(49.69 ± 5.85) days,P < 0.01.Conclusion Systematic strengthening of perioperative functional exercises can significantly improve preoperative vascular conditions,improve the success rate of operation,reduce risk of thrombosis cases,shorten the time of hand edema and the time of fistula in mature.
3.Image features of ielocecus under colonoscopy in intussusceptions children after successful reduction
Haifeng LIU ; Xiaofeng XIONG ; Shenglin YUE ; Lei YU ; Maohua HUANG
Chinese Journal of Digestive Endoscopy 2011;28(2):83-86
Objective To investigate the role of ileocecal valve in children patients with intussus-ceptions by colonoscopy after pneumatic air enema reduction. Methods A total of 106 intussusceptions chil dren patients, who recovered with pneumatic air edema reduction, were recruited to the study. They underwent colonoscopy within 12 hours after reduction. The control group was composed of 103 children patients with both diarrhea and hematochezia. There was no significant difference in age, sex or weight between the two groups.Colonoscopic findings were recorded in terms of slack, swelling, prolapsus, lymphoid hyperplasia and mucosal lesions in ileocecal valve. Results In patients with intussusceptions, the rates of ileocecal valve slack, swelling including prolapsus, lymphoid hyperplasia and mucosal lesions were 61.3%, 33. 9%, 100. 0% and 31.1%, respectively, which were significantly different with those of the control group (P > 0. 05 ). When further divided intussusceptions patients into groups with age more than 1 yr or less, significant differences were also observed in regarding of these features. Conclusion There is a close relationship between morphological and functional changes in ileocecal valve and intussusceptions in children. Ileocolic intussusceptions in patients younger than 1yr is more likely to be due to slack of ileocecal valve, while that in patients older than 1yr is mainly due to swelling or prolapse of ileocecal valve, represented by ileocecal intussuception.
4.Effects of astragalus polysaccharides on lipid metabolism and PPAR-α gene expression in myocardium of diabetic hamsters
Wei CHEN ; Wenjie CHEN ; Yanping XIA ; Yi LU ; Maohua YU
Fudan University Journal of Medical Sciences 2010;37(2):194-197,215
Objective This article was designed to observe the effects of astragalus polysaccharides (APS) on glucose and lipid metabolism, and on expressions of proxisome proliferator activated receptors-α (PPAR-α) and its downstream genes in diabetic hamsters cardiomyopathy. Methods Forty-five hamsters were divided into 3 groups randomly: normal control group (15 normal hamsters), diabetic control group [15 streptozotocin (STZ)-induced diabetic hamsters], and astragalus polysaccharides (APS)-therapy group (15 STZ-induced diabetic hamsters administered with APS 2 g/kg per day orally for 10 weeks). The levels of insulin, C-peptide, myocardial enzymes, glycosylated serum protein (GSP) and lipoprotein of all hamsters were measured. The ultrastructure of myocardium was studied, and the gene and protein expressions of PPAR-α, FATP and ACS were also detected by fluorescent quantitative RT-PCR and Western blot. Results It was shown that Compared with DM group, the levels of GSP, myocardial enzymes and lipoprotein of hamsters in APS-therapy group were lower, the myocardial ultrastructure of hamsters in APS-therapy group was well-protected, and the gene and protein expression of PPAR-α, FATP and ACS of hamsters in APS-therapy group were higher. Conclusions APS is partly effective in treating diabetic cardiomyopathy.
5.Efficacy of tea polyphenols in inhibiting inflammatory damage to islet beta cell of rats with metabolic syndrome
Yanping XIA ; Gang CHEN ; Maohua YU
Chinese Journal of Endocrinology and Metabolism 2010;26(3):229-231
A rat model of metabolic syndrome was induced by high glucose plus high fat diet and treated by tea polyphenols for 10 weeks.The results showed that the levels of fasting blood glucose,triglyceride,cholesterol,low-density lipoprotein cholesterol,and free fatty acid in tea polyphenols treatment group were significantly lower than those in control group(all P<0.05),along with decreased TNF-α,IFN-γ,iNOS mRNA and protein expressions,and IL-1β protein expression in pancreatictissue (all P<0.05).Under electron microscope,more secretory granules in islet beta cells and impoveddisorganization of cellular organ were shown in tea polyphenols treatment group compared with metabolic syndrome group.The results suggest that tea polyphenols are able to protect islet β cells against oxidative damage via inhibiting the production of inflammatory cytokines.
6.Clinicopathotogical features of 67 cases of endometriosis-associated epithelial ovarian carcinoma
Yuan LU ; Maohua LIU ; Yu ZHENG ; Sunwei GUO ; Xishi LIU
Chinese Journal of Obstetrics and Gynecology 2009;44(11):832-836
Objective To investigate clinicopathological features of endometriosis-associated epithelial ovarian carcinoma.Methods Retrospective follow-up study,clinicopathological data from patients with ovarian epithelial carcinoma were retrieved,analyzed and compared.Among the 727 cases,34 were found to originate from endometriosis (group A),33 were found to have co-existing ovarian endometriosis (group B),and the remaining 660 had no ovarian endometriosis at all (group C).Result Seven hundred and twenty-seven epithelial ovarian carcinoma patients were identified and their ehnicopathological data retrieved.Sixty-seven (9.2%) of these cases were found to have coexisting endometriosis.The frequency of malignant tumors arising from ovarian endometriosis in this case series was estimated to be 0.87% (34/3890).The mean (standard deviation) age in groups A,B,and C were(47.2±1.3),(47.8±1.2),(51.2±0.4) years,respectively,with patients in group C being significantly older (P = 0.013).Patients with coexisting ovarian endometriosis were mostly diagnosed at stage Ⅰ (P = 0.000)and having subtype of clear-cell (P =0.000),while other patients were mostly diagnosed at stage Ⅲ (P =0.001),and having subtype of serous carcinoma (P =0.000).The estrogen receptor (ER) positivity was significantly lower in groups A and B than that in group C (22.2%,31.6% vs 43.9%;P =0.018),but the difference in positivity of progestogen receptor among the three groups did not reach statistical significance (22.2%,15.8% vs 35.5%;P =0.082).While the five-year overall survival rate for all patients was 55.6%,significant difference in overall survival among the three groups was found 78.9%,92.8%,51.9%,respectively,for groups A,B and C (P =0.000).Conclusion Patients of endometriosis-associated epithelial ovarian carcinoma,especially patients with tumors arising from endometriosis,were found to be younger,having a significant lower stage and a better survival,and were mostly diagnosed with the subtype of clear-cell.
7.Astragalus polysaccharides improves glycolipid metabolism in myocardium of diabetic hamsters
Wei CHEN ; Wenjie CHEN ; Yanping XIA ; Hongying YE ; Maohua YU
Chinese Journal of Endocrinology and Metabolism 2009;25(4):440-442
e tissue and myocardium, as well as myocardial uhrastructure were well-improved; the gene expressions of PPAR-α and GLUT4 were raised in APSgroup. APS may be partially effective in treating diabetic cardiomyopathy.
8.Effect of Astragalus Polysaccharides on Expression of IL-4 and IFN-γ in Non-obese Diabetic Mice
Xiaoyan WU ; Wei CHEN ; Maohua YU
Chinese Journal of Rehabilitation Theory and Practice 2008;14(2):147-149
Objective To investigate the effect of astragalus polysaccharide(APS)on expression of interleukin-4(IL-4)and interferon-γ(IFN-γ)in non-obese diabetic(NOD)mice.Methods 20 NOD mice were randomly divided into the APS group and control group with 10 animals in each group.The mice of the APS group took APS 2 g/kg/d orally for two months.The animals of the control group took same quantity saline.The incidence rate of type 1 diabetes mellitus of two groups was calculated,and pancreatic histopathology was observed with microscope,and expression of IL-4 and IFN-γ were examined with RT-PCR for both APS group and control group.Results The incidence rate of type 1 diabetes mellitus of the APS group was lower than the control group,and histopathology of islets were more protected,expression of IFN-γ was lower and expression of IL-4 was higher in the APS group.Conclusion APS may correct the imbalance of cytokines.
9.Relationship between Serum Content of Adiponectin and Hepatic Steatosis in the Elderly
Xiaoyan WU ; Wenjie CHEN ; Yi LU ; Xiaomei SHI ; Maohua YU
Chinese Journal of Rehabilitation Theory and Practice 2007;13(12):1176-1178
Objective To investigate the change of the serum content of adiponectin in the elderly, and the relationship between hepatic steatosis and the serum content of adiponectin and metabolic syndrome.Methods 264 elderlies were divided into the hepatic steatosis group (87 cases) and control group (177 cases) after B type ultrasonograph examination. The height, weight, waist circumference and levels of serum lipid, glucose, insulin and adiponectin of all cases in the two groups were measured. The relationship between above variables and hepatic steatosis was analyzed. The multiple logistic regression analysis was used to test the efficacy of adiponectin and metabolic syndrome for predicting the probability of having hepatic steatosis in the elderly.Results For the hepatic steatosis group, the serum content of adiponectin was significantly lower than that of the control group ( P<0.01), the frequency of metabolic syndrome was significantly higher than that of the control group ( P<0.01), and the body mass index, waist circumference, blood glucose (fasting blood glucose and postprandial blood glucose), homeostasis model assessment-insulin resistance index, total cholesterol, triglyceride and low density lipoprotein cholesterol increased and high density lipoprotein cholesterol decreased. Logistic regression analysis showed that serum content of adiponectin and metabolic syndrome were associated with the probability of hepatic steatosis.Conclusion The serum content of adiponectin and metabolic syndrome are useful indices for the prediction of hepatic steatosis.
10.Study on the levels of serum insulin-like growth factor 1 in patients with metabolic syndrome
Yanyan HUANG ; Xiaozhe LU ; Maohua YU
Chinese Journal of Geriatrics 2003;0(07):-
Objective To investigate the relationship between serum insulin-like growth factor 1 (IGF1) and metabolic syndrome ( MS) . Methods Four hundred and sixty-five subjects were enrolled and divided into two groups: MS group( n = 255) and non-MS group as control(n = 210). Fasting levels of blood glucose (FBG), insulin (Ins) , C peptide (Cp) , cholesterol (Cho) , triglyceride (TG), lower-density lipoprotein cholesterin ( LDL-C) , higher-density lipoprotein cholesterin ( HDL -C), lipoprotein a (Lpa), serum IGF1, postprandial 2 hours blood glucose (PBG), and BMI were measured in these persons. Results The levels of IGF1, Cp, FBG, PBG, CT, TG, LDL-C, BMI were higher, and HDL-C was lower in MS group than those in non-MS group (all P


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