1.Application and Value of Authentication Methods in the Study on Traditional Chinese Medicine Classics
Lufeng ZHENG ; Zheng GE ; Xiang LI ; Guangkun CHEN ; Fanglin HU ; Yanhong YANG ; Hongtao LI
Journal of Traditional Chinese Medicine 2026;67(4):349-354
This paper systematically reviewed the concept of authentication studies on traditional Chinese medicine (TCM) classics and the research achievements of scholars across historical and contemporary periods. We categorized the authentication studies on TCM classics into four types, including work-oriented authentication research, metho-dological studies on authentication, extended authentication research, and single-book authentication. Multiple methods were applied comprehensively, including investigating bibliographic documents of successive dynasties, analyzing the academic contents of medical books, studying the textual characteristics of medical books, examining the cited references in medical books, verifying the biographies of authors, and analyzing the interpolations and accretions in medical books, to distinguish the authenticity of TCM classics. The academic value of authenticity identification of TCM classics is concluded in three aspects,i.e. it serves as an important means to distinguish authenticity from falsehood in TCM classics, an important guarantee for inheriting the essence of TCM literature, and a key to unlocking the academic treasure trove of TCM classics and achieving inheritance-based innovation, which will lay a solid documentary foundation for constructing identification methodologies and standardized systems.
2.Study on residents’willingness to pay for community pharmacies’medication guidance services and its influencing factors
Mingyue LI ; Jiangtao ZHANG ; Zhen KANG ; Hui GAO ; Wentao LIAO ; Lufeng CHENG
China Pharmacy 2025;36(22):2766-2771
OBJECTIVE To explore the willingness to pay (WTP) of Urumqi residents for community pharmacies’ medication guidance services and its influencing factors, so as to provide data support for the optimization of community pharmacy services and the establishment of a fee structure for medication guidance services. METHODS A stratified quota sampling method was employed to select 14 communities in Urumqi City. From April to June 2025, a combined offline and online questionnaire survey was conducted among adult residents in these communities. The contingent valuation method was used to construct three hypothetical scenarios (namely, basic, enhanced and extended services) of medication counselling in community pharmacies to assess residents’ WTP for these services. Binary Logistic regression was employed to analyze the influencing factors of WTP. RESULTS A total of 576 valid questionnaires were obtained. Under the scenarios of basic, enhanced and extended services, 38.54%, 49.65% and 67.19% of the respondents expressed WTP for the services, respectively. Occupational type, type of basic medical insurance, annual income, perception of pharmacists’ profession, and acceptance level of the service were identified as major influencing factors for WTP (P<0.05). CONCLUSIONS The willingness of residents in Urumqi to pay for medication counseling services provided by pharmacists in community pharmacies significantly increases with the enrichment of service content. It is recommended to incorporate basic medication counselling services provided by pharmacists in community pharmacies into medical insurance payment, while value-added services should be partially or fully self-paid by residents. Additionally, efforts should be made to strengthen the promotion of the professional and service value of licensed pharmacists, so as to facilitate the high-quality development of pharmaceutical care.
3.Single-Neuron Reconstruction of the Macaque Primary Motor Cortex Reveals the Diversity of Neuronal Morphology.
Siyu LI ; Yan SHEN ; Yefei CHEN ; Zexuan HONG ; Lewei ZHANG ; Lufeng DING ; Chao-Yu YANG ; Xiaoyang QI ; Quqing SHEN ; Yanyang XIAO ; Pak-Ming LAU ; Zhonghua LU ; Fang XU ; Guo-Qiang BI
Neuroscience Bulletin 2025;41(3):525-530
4.Real world study on antiviral efficacy and safety in patients with normal ALT chronic hepatitis B
Jing WANG ; Jiaqi WANG ; Fang CHEN ; Jie XIA ; Lufeng LI ; Qing MAO
Chongqing Medicine 2025;54(1):138-141
Objective To study the efficacy and safety of antiviral therapy in the patients with normal ALT chronic hepatitis B(CHB).Methods The clinical data of the patients with normal ALT CHB visiting in this hospital from December 2019 to December 2023 were collected.The patients were divided into the low vi-ral load group(HBV DNA<2×106 IU/mL,n=76)and high viral load group(HBV DNA≥2×106 IU/mL,n=10).ETV,TDF and TAF were adopted to conduct the single drug antivirus therapy.The basic informa-tion,demographic characteristics,HBV DNA levels in initial treatment and after 12,24,36,48 weeks of treat-ment,estimated glomerular filtration rate(eGFR)were collected.The rate of complete virological response(CVR)at each time point conducted the statistics for evaluating the effect.The drug safety was evaluated by the eGFR level in 48 weeks of treatment.Results The CVR rates in 12,24,36 weeks of treatment in the low viral load group were 81.6%,94.7%,100.0%and 100.0%respectively,which in the high viral load group were 40.0%,80.0%,80.0%and 80.0%respectively.There was no significant change in eGFR level(109.41±170.57)mL·min-1·1.73 m-2 at 48 weeks of treatment compared with baseline(108.47±110.83)mL·min-1·1.73 m-2(P>0.05).The ALT and creatinine levels during the treatment process in all the patients were not increased.There was no case of drug withdrawal and drug change due to the drug side effects.Conclusion The overall efficacy and safety of ETV,TDF and TAF monotherapy are good in CHB pa-tients with a family history of cirrhosis or liver cancer and normal ALT.The patients with high viral load at baseline are less likely to achieve CVR in 48 weeks of treatment.
5.Research on medicinal and food functions of Atractylodis Macrocephalae Rhizoma in the past dynasties
Lufeng ZHENG ; Zilin CHEN ; Zhilai ZHAN ; Hongtao LI ; Guangkun CHEN
International Journal of Traditional Chinese Medicine 2025;47(5):577-585
By sorting out the records of Atractylodis Macrocephalae Rhizoma as food and medicine, this article believed that Atractylodis Macrocephalae Rhizoma as the same origin of medicine and food for a long history, the earliest in the Qin and Han Dynasty Shen Nong Ben Cao Jing: "Zhu, bitter and warm, having efficacy for cold, dampness, paralysis of dead muscles, and spasm; antiperspirant, removing heat, digesting food, and be used as decoction bait; taking for a long time, losing weight and prolonging life, and don't be hungry". On the basis of Shen Nong Ben Cao Jing, later doctors continue to conduct long-term clinical observation and compatibility of its medicine and food efficacy, which is widely used in internal, external, gynaecology, pediatrics, skin and other departments, to treat spleen and stomach diseases, epidemic diseases, kidney diseases, etc. At the same time of clinical practice, Atractylodis Macrocephalae Rhizoma is also widely used in the folk for dietary therapy, including decoction bait, ointment, decoction, soup and other edible methods. Therefore, as a medicine and food and health preservation product, Atractylodis Macrocephalae Rhizoma has great development potential in daily health care and disease diagnosis and treatment with the effects of non-toxic, satiety and longevity.
6.Research on the current situation and influencing factors of nurses′growth mindset ability
Yujiao YANG ; Yanyan ZHANG ; Lufeng PENG ; Jingxian SUN ; Li GAO ; Dan LI ; Xinxin YANG ; Youru XUE
Chinese Journal of Practical Nursing 2024;40(11):863-869
Objective:To explore the current situation of nurses′growth mindset ability and study its related influencing factors, so as to serve as a reference for improving nurses′ growth mindset ability.Methods:This was a cross-sectional survey, and 310 nurses from 5 tertiary hospitals in Shandong Province, Shanghai City, and Guangdong Province were selected as the survey subjects from April to June 2022 using convenience sampling method. The General Information Questionnaire, the Nurses′ Growth Mindset Assessment Scale, the Psychological Adaptability Self-Assessment Scale, the Chinese Big Five Personality Inventory Brief Version and the Team Psychological Safety Atmosphere Scale were used to investigate the growth mindset ability of nurses and its influencing factors.Results:Finally, 307 valid questionnaires were collected. There were 46 males and 261 females, aged 20-50 years old. The scores of the Nurses′ Growth Mindset Assessment Scale were (108.89 ± 29.32) points, the scores of the Psychological Adaptability Self-Assessment Questionnaire were 10.0(0.0, 20.0) points, the scores of the Chinese Big Five Personality Inventory Brief Scale were (162.37±43.82) points, and the scores of the Team Psychological Safety Atmosphere Scale were (55.84 ± 15.12) points. The highest education level ( B = 0.028, P = 0.040), professional title ( B = 0.033, P = 0.032), family economic support ( B = 0.025, P = 0.048), Chinese big five personality ( B = 0.039, P = 0.037), team psychological safety atmosphere ( B = 0.600, P<0.001) and psychological adaptability ( B = 0.313, P<0.001) had a significant effect on nurses′ growth mindset ability. Conclusions:The growth mindset ability of nurses is at the upper middle level, and the educational background, professional title, family economic support, personality characteristics, team psychological safety atmosphere and psychological adaptability of nurses are the significant influencing factors. Hospitals, social and health education systems can combine influencing factors to provide a harmonious working atmosphere for nurses, focusing on the improvement of nurses′ academic qualifications and the promotion of professional titles, cultivating nurses′ psychological adaptability, improving nurses′growth mindset ability, and improving the overall quality of the nursing service team.
7.Advances in research on neoadjuvant chemoradiotherapy combined with immune checkpoint inhibitors for locally advanced rectal cancer
Shuangshuang HOU ; Lufeng CHEN ; Gehong ZHANG ; Juan MA ; Xianfeng LI
Chinese Journal of Radiological Medicine and Protection 2024;44(8):718-724
Neoadjuvant chemoradiotherapy (nCRT) followed by total mesorectal excision (TME) and adjuvant chemotherapy serves as a traditional standard treatment for locally advanced rectal cancer (LARC). However, such treatment suffers low pathological complete response (pCR) rates, which are merely less than 15%, and low anal-preservation rates, failing to meet the demand of patients for high quality of life. Recently, total neoadjuvant therapy (TNT) whereby postoperative adjuvant chemotherapy is performed preoperatively has further increased the pCR rate, gradually becoming a novel therapeutic approach. Nevertheless, the pCR rate of TNT remains below 30%. Presently, immune checkpoint inhibitors (ICIs) have been proved to be highly successful in treating various solid tumors, yet they are scarcely employed to treat LARC. In recent years, many clinical trials have been conducted to explore the application of nCRT combined with ICIs in the treatment of LARC. This paper reviews the advances in research on this therapy.
8.Effects of Rehabilitation Training Combined with Acupuncture on Upper Limb Function of Stroke Patients Based on Kinect
Rujie YAO ; Lufeng YIN ; Qiurong XIE ; Bo SHENG ; Zhenhu LI ; Qing CHEN ; Nan LI ; Xiangbin WANG
Journal of Medical Biomechanics 2023;38(1):E182-E188
Objective To investigate the effect of rehabilitation training combined with acupuncture ( RTA) on upper limb function of stroke patients by Kinect. Methods Stroke patients with upper limb dysfunction werrandomly divided into control group (rehabilitation training) and treatment group ( RTA), with 15 cases in each group. The modified Barthel Index ( MBI), Fugl Meyer assessment ( FMA), and Wolf motor function test (WMFT) were compared between two groups before and after treatment. The changes in motor time ( MT), motor unit number (MUN), index of curvature (IC), elbow flexion angle (EFA), shoulder flexion angle (SFA),and shoulder adduction angle ( SAA) during three actions, namely, placing forearm on the table, extending elbow and drinking water, were evaluated by Kinect and then compared between two groups before and after treatment. Results After 6 weeks of intervention, the scores of MBI, FMA, WMFT and elbow extension in treatment group were higher than those in control group (P<0. 05). The scores of MBI, FMA, WMFT and three actions after treatment were higher than those before treatment (P<0. 05). For three actions, the improvement of MT, MUN, IC, EFA, SFA, and SAA in treatment group were better than those in control group ( P< 0. 05). Compared with pre-treatment, for the action of forearm placement on the table and elbow extension, both treatment group and control group showed an increase in EFA (P<0. 05), and a decrease in MT, MUN, IC, SFA and SA (P<0. 05). For the action of drinking water, both treatment group and control group showed an increase in EFA and SAA (P< 0. 05), and a decrease in MT, MUN, IC and SAA ( P< 0. 05). Conclusions RTA can improve the upper limb function of stroke patients. Kinect can accurately reflect the changes in upper limb function of stroke patients, and it is suitable for clinical work.
9.Clinical effect of in vitro fenestration on reconstruction of left subclavian artery in endovascular treatment of aortic dissection
Donglin LI ; Lufeng CHEN ; Rongbin LI ; Xudong CAI
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery 2023;30(03):403-409
Objective To investigate the effect of in vitro fenestration on reconstruction of left subclavian artery in endovascular treatment of aortic dissection. Methods A total of 89 patients with aortic dissection involving left subclavian artery were treated by endovascular treatment in the Second Affiliated Hospital of Fujian Medical University from February 2017 to January 2020. There were 44 patients in the test group, including 36 males and 8 females, with an average age of 58.02±13.58 years. There were 45 patients in the control group, including 35 males and 10 females, with an average age of 54.10±12.32 years. The left subclavian artery was reconstructed by in vitro fenestration in the test group and by chimney technique in the control group. The clinical data were compared between the two groups. Results The operation time of the test group was longer than that of the control group (126.16±7.53 min vs. 96.49±6.52 min, P<0.01). The median follow-up time was 31 (13-48) months. The incidence of endoleak in the test group (4.7%) was lower than that in the control group (18.6%, P=0.04) during the follow-up. There was no statistical difference in the incidence of stroke, myocardial infarction, false lumen thrombosis, retrograde aortic dissection or left subclavian artery occlusion between the two groups (P>0.05). Conclusion In vitro fenestration for reconstructing left subclavian artery in thoracic endovascular aortic repair of aortic dissection is safe and feasible, which is worthy of further clinical promotion.
10.Development and reliability and validity test of Nurses′ Growth Mindset Assessment Scale
Yuhui SHI ; Youru XUE ; Lufeng PENG ; Yating ZHU ; Yuan LI
Chinese Journal of Practical Nursing 2023;39(9):707-711
Objective:To construct a Nurses′ Growth Mindset Assessment Scale, and to test the reliability and validity of the scale, so as to provide an assessment tool for accurately assessing nurses′growth mindset ability.Methods:From June to October 2021, taking the growth mindset theory as the research framework, at the same time, the related researches on the growth mindset were reviewed and analyzed, the item pool of the scale was comprehensively constructed, and the formal version of the scale was formed through factor analysis, Delphi method and other research methods. A total of 578 nurses from Qilu Hospital of Shandong University and Shandong Provincial Hospital were investigated to test the reliability and validity of the scale by simple sampling method.Results:The constructed formal scale consisted of 31 items and 3 dimensions. The 3 dimensions were self-awareness, attitude towards challenges and resilience to setbacks. The cumulative variance contribution rate was 65.954%. The Cronbach′s alpha coefficient was 0.926, and the Spearman-Brown split-half reliability coefficient was 0.750.Conclusions:Nurses′ Growth Mindset Assessment Scale has good reliability and validity, and can be used to evaluate the nurses′ growth mindset ability.

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