1.A retrospective study on risk factors and pharmacological treatment of arterial hypertension
Unurjargal Yadmaa ; Urantsetseg Khurelbaatar ; Ariunaa Zundui ; Batkhuyag Purevjav ; Oyunbileg Sharavdorj ; Lkhagvasuren Tsolmon ; Munkhdelger Baasan ; Tungalag Dagdanbazar ; Tserenchunt Ganbold ; Saingerel Mendgerel ; Maralmaa Lkhagvasuren ; Ider Sarantuya ; Munkhtulga Erdenetsetseg
Mongolian Pharmacy and Pharmacology 2026;28(1):94-98
Abstract
According to the World Health Organization (WHO) report in 2023, arterial hypertension (HTN) remains
one of the leading causes of global morbidity, with an estimated 1.3 billion individuals diagnosed worldwide. Among them, 42% were receiving antihypertensive treatment, and only 21% achieved adequate blood pressure control. In the United States, 47.7% of the adult population is diagnosed with hypertension, with prevalence increasing significantly with age [1,2]. Multiple factors such as lifestyle, body mass index (BMI), age, sex, genetics, and physical inactivity are well-documented contributors to hypertension, as evidenced by both international and local studies. Specifically, individuals classified as obese demonstrate a higher prevalence of hypertension based on BMI categorization.
However, in Mongolia, limited studies have investigated the contributing factors and treatment outcomes of hypertension, highlighting the necessity of this study.
A retrospective study was conducted by reviewing the medical records of 50 inpatients diagnosed with arterial hypertension (ICD-10 codes I10–I15) who were admitted to Sindura-Med Hospital between 2023 and 2024.
1. In patients with stage 1 and 2 arterial hypertensions, age, mean systolic and diastolic blood plessure, heart rate and elevated cholesterol levels were found to be correlated with body mass index (BMI). Among smokers, the risk of developing cardiovascular diseases is projected to increase over the next 10 years
2. In the hypertensive group aged 60 years and older, echocardiographic examination revealed structural and functional abnormalities.
3. In the pharmacological management of arterial hypertension, calcium channel blockers, angiotensin
converting enzyme (ACE) inhibitors, combination preparations, and diuretics were the most commonly
prescribed medications.
2.Antibiotic consumption in infants and toddlers
Gan-Undral Munkhjargal ; Ariunaa Zundui ; Tserenchunt Ganbold ; Munkhdelger Baasan ; Lkhagvasuren Tsolmon ; Oyunbileg Sharavdorj ; Unurjargal Yadmaa
Mongolian Pharmacy and Pharmacology 2025;26(1):17-21
Introduction:
Antibiotics are commonly prescribed in paediatrics.1 Children were 1.3 times more likely to be treated with antibiotics compared to adults.2 Especially, antibiotic prescription is higher in children aged under 5 years.3
Purpose:
To identify the most widely used antibiotics in the age group of 0-5.
Objectives of the study:
1. To identify the most widely used antibiotics and classify them by pharmacological group
2. To analyze the pharmaceutical dosage forms of commonly prescribed antibiotics for infants and toddlers
Methods:
In our study, we selected 20 pharmacies from 6 districts (Bayanzurkh, Bayangol, Khan-Uul, Songinokhairkhan, Chingeltei, and Sukhbaatar) of Ulaanbaatar city using a single random sampling method. A total of 496 antibiotic prescriptions written for children aged 0-5 years in 20 pharmacies were analyzed. Antibiotic prescription forms for children aged 0-5 years registered in the pharmacies in November, December 2023, and January 2024 were collected. The results were processed using “SPSS 29.0.2” program.
Result:
Among a total of 496 antibiotic prescriptions written for children, 341 were written in solid dosage form and 155 were in liquid dosage form (suspension). Amoxicillin 250 mg and Amoxiclav 312.5 mg were mostly used from Penicillin group for the treatment of infants and toddlers. Clarithromycin 125mg/5ml from Macrolide group had an important role in treatment. Cefixime 400 mg from the Cephalosporin group was used in some cases such as diarrhea and vomit.
Conclusions
1. Amoxicillin, Amoxiclav, Clarithromycin (Penicillin, Macrolide) antibiotics are the most widely used in the treatment
of infants and toddlers.
2. It has concluded that antibiotic prescriptions for infants and toddlers mainly include solid and suspension antibiotics.
3.Coronary Microcirculation in Acute Myocardial Infarction and the Clinical Significance of Artificial Intelligence-Based Software
Batzaya Ts ; Surenjav Ch ; Batmyagmar Kh ; Narantuya D ; Lkhagvasuren Z ; Tsolmon U
Mongolian Journal of Health Sciences 2025;88(4):231-237
Background:
Cardiovascular diseases (CVDs) is a third leading cause of non-communicable diseases and a leading cause
of mortality in Mongolia. Among these, acute myocardial infarction (AMI), a complication of coronary artery disease
(CAD), is a leading cause of cardiovascular mortality. In patients with AMI, both epicardial artery blood flow, observed
through coronary angiography, and coronary microcirculatory dysfunction (CMD) play critical roles in the disease’s
pathophysiology. Recent advancements have introduced artificial intelligence (AI)-based softwares which are capable of
analyzing coronary blood flow from coronary angiography images. The AI based softwares can assess not only epicardial
blood flow but also CMD in recent studies. In this review, we discussed the role of CMD in pathophysiology of AMI,
diagnostic approaches, the application of AI-based technologies, their clinical significance, and future directions.
Aim:
This review aims to explore the pathophysiological relationship of coronary microcirculatory dysfunction (CMD)
in the context of acute myocardial infarction (AMI), diagnostic methodologies, the application of artificial intelligence
(AI)-based technologies, and their clinical significance.
Hypotheses:
1. AI-based software allows for highly accurate assessment of coronary microcirculation during AMI.
2. CMD during AMI is associated with structural and functional changes in the heart.
3. CMD during AMI is related to disease prognosis and patient outcomes.
Methodology::
This narrative review was compiled using a systematic and logical approach, based on publicly available
recent clinical and biomedical research literature addressing the above hypotheses.
Conclusion
In recent years, AI-based image processing software has been developed to analyze angiographic images obtained during percutaneous coronary intervention (PCI) and treatment procedures. These tools show significant promise
for early detection and improved diagnosis of CMD during AMI, as well as for better assessment of short- and long-term
patient risk.
Result Analysis
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