Uncariae Ramulus Cum Uncis has the effects of wind-extinguishing and convulsion resolving,clearing heat and liver smoothing It can be used to treat cancer,cardio-cerebrovascular diseases,neurodegenerative diseases,depression and other diseases.Studies have shown that Uncariae Ramulus Cum Uncis has significant anti-tumor activity and has inhibitory effects on many kinds of cancers,and monoterpene indole alkaloids are the main source of pharmacological effects of Uncariae Ramulus Cum Uncis.This paper reviewed the research related to the anti-tumor effect of monoterpene indole alkaloids from Uncariae Ramulus Cum Uncis in the last decade,and the anti-tumor mechanism was summarized to offer theoretical basis for the further study of monoterpene indole alkaloids in Uncariae Ramulus Cum Uncis.

Uncariae Ramulus Cum Uncis has the effects of wind-extinguishing and convulsion resolving,clearing heat and liver smoothing It can be used to treat cancer,cardio-cerebrovascular diseases,neurodegenerative diseases,depression and other diseases.Studies have shown that Uncariae Ramulus Cum Uncis has significant anti-tumor activity and has inhibitory effects on many kinds of cancers,and monoterpene indole alkaloids are the main source of pharmacological effects of Uncariae Ramulus Cum Uncis.This paper reviewed the research related to the anti-tumor effect of monoterpene indole alkaloids from Uncariae Ramulus Cum Uncis in the last decade,and the anti-tumor mechanism was summarized to offer theoretical basis for the further study of monoterpene indole alkaloids in Uncariae Ramulus Cum Uncis.

OBJECTIVE To determine the sensitivity of Vibrio vulnificus to 23 kinds of antibacterial drugs,and offer the evidence for clinical V.vulnificus infections treatment.METHODS Isolated 11 strains of V.vulnificus from the patients blood and blisters of infected parts,using ATB automatic identification and susceptibility testing to measure the vitro drug sensitivity of the bacteria.RESULTS The susceptibility of the bacteria to the 22 kinds of commonly used antibiotics showed 100% sensitivity,the rate of ciprofloxacin sensitivity was 72%.CONCLUSIONS It is sensitive to commonly used semi-synthetic penicillin,cephalomycin,carbapenem,aminoglycosides,the third generation cephalosporins,fluoroquinolones and so on,all these above drugs may be chosen to treat the V.vulnificus infection.

Objective To investigate the objectivity and comprehensiveness of Response Evaluation Criteria of Traditional Chinese Medicine for Solid Tumor(REC-TCM-ST) in the therapeutic effect evaluation of Chinese medicine for late non-small-cell lung cancer(NSCLC).Methods A retrospective study was carried out in 104 NSCLC patients in the stages of Ⅲ~Ⅳ.Of 104 patients,53 received traditional Chinese medicine(TCM group),and 51 received western medicine(WM group).The therapeutic effect in the two groups was evaluated with both REC-TCM-ST and Response Evaluation Criteria in Solid Tumor(RECIST).Results The REC-TCM-ST evaluation results showed that the effective rate on relieving tumor mass in TCM group was lower than that in WM group(P0.05);the symptom of weakness was much relieved,and effect on Karnofsky score was good in TCM group as compared with that in WM group(P0.05).As for the survival patients,TCM group had a median survival period of(8.0?1.2) months,and survival rates for half a year,one year and two years were 60.38%,24.53% and 3.77% respectively;WM group had a median survival period of(5.9?0.4) months,and survival rates for half a year,one year and two years were 41.18%,15.69% and 1.96% respectively.The RECIST evaluation results showed that the total effective rate and the total stable rate were 9.62% and 72.12% respectively,while were 34.62% and 84.62% respectively when evaluated with REC-TCM-ST,the difference being significant(P