1.Analysis of recurrence pattern and prognosis of patients with cervical envenoms and pelvic lymph node metastasis
Ying XIONG ; Lizhi HANG ; Min ZHENG ; Luanhong WANG ; Pengfei DENG ; Jihong LIU
Chinese Journal of Obstetrics and Gynecology 2008;43(6):425-428
0bjective To investigate the pattern of disease relapse and prognostic risk factor of patients with cervical carcinoma and pelvic lymph node metastasis.Methotis A total of 124 cases of International Federation of Gynecology and Obstetricfi(FIG0)I bl-Ⅱ a cervical carcinoma with pelvic node metastasis who were treated at the Cancer Center of Sun Yat-sen University during January 1994 to December 2001 were selected for this study.Prognosis and recurrence were retrospectively analyzed using the clinico.pathological data.Results The overall 5 year flun,ival and 5 year disease-free survival were 63.3% and 61.4%.respectively.Overall recurrence rate was 39.5%(49/124),among which intra-pelvic relapse (61.0%,25/41)was significantly more common than extra-pelvic relapse(31.7%,13/41;P=0.008).Multivariate analysis identified involvement of common iliac node as an independent prognostic factor(P=O.035).According to this factor,node-positive patients could be divided into low risk group(without common iliac node involvement,104 cases)and hiSh risk group(with common iliac node involvement,20 cases).The 5 year disease-free survival were 69.4%and 24.5%respectively,with a significant difference(P=0.003).Intra.pelvic relapse was observed in 22.1%(23/104)of low risk and 25.0% (5/20)of high risk group respectively,with no significant difference(P>0.05).However extra-pelvicrelapse wag seen in 7.7%(8/104)of low risk and 40.0%(8/20)of hish risk group,with a significant difference(P<0.01).Conclusions Common iliac node involvement is a significant factor influencing the prognosis of patients with cervical carcinoma and pelvic lymph node metastasis.Patients with positive common iliae nodes have significantly decreased 5 year disease.free survival and hishcr extra-pelvic disease recurrence rates compared with those whose common iliac nodes are negative.These findings provide impo.rtant data for design of individualized treatment mode.
2.Hirsch index comparison and clustering analysis of Chinese medical subjects
Ren LI ; Hang SU ; Lizhi MA ; Erqing LEI
Chinese Journal of Medical Science Research Management 2008;21(4):214-216
Hirsch index or h-index of a subject means that the subject has h published papers which are cited at least h times for each.This index is considered as both quantity and quality of the SHbiect's academic outcome.In this paper the data showed that the h-indexes of the Chinese medical SUbiects were different.The SUbiect's h-index could be used as a balance factor.which made the outcome of scientists from different SUbiects comparable.Using h-index and the other 2 indexes.Chinese medical snbiects were clustered into 4 groups,which could be used as a guideline for classified management and the evaluation of the medical subjects
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