This report described a case of neonatal alloimmune thrombocytopenic purpura presenting with generalized petechiae. The infant was admitted at Nanfang Hospital, Southern Medical University on March 30, 2022, following detection of wide spread petechiae 30 minutes post-delivery. Blood tests revealed severe thrombocytopenia (platelet count 5×10 9/L) with leukopenia, decreased hemoglobin, and hepatomegaly, though coagulation function remained normal. Initial treatments—random donor platelet transfusion, and intravenous immunoglobulin—proved ineffective. Pretreatment blood samples showed strongly positive platelet antibodies (3+). Further typing confirmed human leukocyte antigen (HLA) antibodies in both infant and mother, establishing HLA-negative neonatal alloimmune thrombocytopenia. HLA-negative platelet transfusion resolved petechiae and normalized platelet counts, enabling discharge on postnatal day 14. Subdural hemorrhage was detected on MRI at day 29. Platelet levels remained normal at six-month follow-up, with age-appropriate development confirmed at 2.5 years.

This report described a case of neonatal alloimmune thrombocytopenic purpura presenting with generalized petechiae. The infant was admitted at Nanfang Hospital, Southern Medical University on March 30, 2022, following detection of wide spread petechiae 30 minutes post-delivery. Blood tests revealed severe thrombocytopenia (platelet count 5×10 9/L) with leukopenia, decreased hemoglobin, and hepatomegaly, though coagulation function remained normal. Initial treatments—random donor platelet transfusion, and intravenous immunoglobulin—proved ineffective. Pretreatment blood samples showed strongly positive platelet antibodies (3+). Further typing confirmed human leukocyte antigen (HLA) antibodies in both infant and mother, establishing HLA-negative neonatal alloimmune thrombocytopenia. HLA-negative platelet transfusion resolved petechiae and normalized platelet counts, enabling discharge on postnatal day 14. Subdural hemorrhage was detected on MRI at day 29. Platelet levels remained normal at six-month follow-up, with age-appropriate development confirmed at 2.5 years.

OBJECTIVE： To investigate the current situation of faculty development research in TCM colleges and universities， to analyze the hot spots and deficiencies in the research， and provide reference for the colleagues to engage in related research and carry out corresponding work. METHODS： With “faculty” as the title or keyword and “TCM university” or “TCM college” as author institution， the literatures about faculty development researches published by the TCM colleges and universities were retrieved from CNKI， VIP and Wanfang database during database establishment to Nov. 19th， 2018. Note Express 3.0 software was used to extract the parameters such as publish year， source journals， publish institution， the authors， cited frequency， fund assistance and keywords. Bibliometric statistics and analysis was performed by using SPSS 19.0 software. RESUITS： Totally 1 183 valid literatures were obtained， mainly for periodical literatures （1 144 literatures）. The total number of literatures was on the rise， and reached to peak value of 118 in 2016. 1 144 literatures were published in 408 journals. The top 6 authors with high production were Liu Jingli （6 literatures）， Liang Xinyue， Liu Na， Liu Yanping， Xu Nanyang， Yan Xiaotian （5 literatures respectively）； the top one institution was Nanjing University of TCM （89 literatures）. 653 （55.20％） literatures have cited records， most of them （457 literatures， 38.63％） were cited 1-3 times， and the average cited frequency was 2.15 times； the ratio of funded papers of state ministries and commissions were less than 3％； 7 098 keywords were extracted and high-frequency keywords were 31， involving “faculty” and “young teachers”. CONCLUSIONS： The research on faculty development in TCM colleges and universities has become increasingly active， but the core research author has not yet formed. The research still lacks of sustainability and comprehensiveness， and the research quality needs to be further improved.

Alzheimer′s patients bring heavy burden to their family and society, causing potential safety prob-lems unable to escort for a long time with the family, physical constraints between protection and between self-es-teem and the mental health law,the quality of life and life values produce a series of contradiction and ethical is-sues,also make close contact with their nursing staff have to face the moral and ethical dilemma.The suggestions are:Hospital provides professional full-time, professional pension caregivers of alzheimer′s patients for long-term care, Strengthen the communication of nursing staff and patients′families, Reasonable and legitimate use tools, Perfect medical system construction, buildMedical support combinedcare system, Carry out the comprehensive rehabilitation nursing intervention, improve the patients quality of life, Change service concept, strengthening the study of ethical knowledge and application to promote the doctor-patient relationship.