1.Exploring the Pathway of Qi Theory and Its Clinical Implications
Lilei XU ; Xuewen WU ; Ke'an ZHU
Journal of Zhejiang Chinese Medical University 2025;49(5):601-605
[Objective]To review and summarize the different explanations of the pathway of Qi theory from various physicians and scholars,thereby promoting the broader clinical application of the pathway of Qi theory.[Methods]Relevant passages on the pathway of Qi in classical medical texts and interpretations from various historical physicians were reviewed and analyzed.Contemporary research findings were integrated to explore the unique functions of the pathway of Qi in conjunction with modern anatomical discoveries,hypothesizing its potential structures.Existing clinical applications of the pathway of Qi theory were compiled,and its possible mechanisms of action were preliminarily analyzed.[Results]The pathway of Qi theory integrates the meridian system with the principles of Biao-Ben-Gen-Jie,establishing a bidirectional pathway connecting internal organs,meridians and body cavity spaces.The pathway of Qi exhibits the following characteristics:As a lateral"shortcut",it directly links pathological regions with stimulation points,shortening the pathway of Qi flow;Under stress conditions,it serves as a channel for Qi circulation,maintaining continuity of Qi flow;Through cavity structures,it forms a network connecting internal organs and meridians,providing reserves and regulatory spaces for Qi and blood circulation;It stimulates and regulates Qi flow,related to the phenomena such as heat-sensitive acupoints and the mechanisms of acupuncture and moxibustion.Based on the physiological characteristics of the pathway of Qi,the flexible application of the pathway of Qi theory can provide support for clinical practices such as Shu-Mu point selection and region-specific treatment.[Conclusion]As a crucial component of meridian theory,the pathway of Qi theory has made significant strides in research of conceptualization,semantics and anatomical delineation.Further exploration is warranted to enhance its guidance in clinical applications.
2.Exploring the Pathway of Qi Theory and Its Clinical Implications
Lilei XU ; Xuewen WU ; Ke'an ZHU
Journal of Zhejiang Chinese Medical University 2025;49(5):601-605
[Objective]To review and summarize the different explanations of the pathway of Qi theory from various physicians and scholars,thereby promoting the broader clinical application of the pathway of Qi theory.[Methods]Relevant passages on the pathway of Qi in classical medical texts and interpretations from various historical physicians were reviewed and analyzed.Contemporary research findings were integrated to explore the unique functions of the pathway of Qi in conjunction with modern anatomical discoveries,hypothesizing its potential structures.Existing clinical applications of the pathway of Qi theory were compiled,and its possible mechanisms of action were preliminarily analyzed.[Results]The pathway of Qi theory integrates the meridian system with the principles of Biao-Ben-Gen-Jie,establishing a bidirectional pathway connecting internal organs,meridians and body cavity spaces.The pathway of Qi exhibits the following characteristics:As a lateral"shortcut",it directly links pathological regions with stimulation points,shortening the pathway of Qi flow;Under stress conditions,it serves as a channel for Qi circulation,maintaining continuity of Qi flow;Through cavity structures,it forms a network connecting internal organs and meridians,providing reserves and regulatory spaces for Qi and blood circulation;It stimulates and regulates Qi flow,related to the phenomena such as heat-sensitive acupoints and the mechanisms of acupuncture and moxibustion.Based on the physiological characteristics of the pathway of Qi,the flexible application of the pathway of Qi theory can provide support for clinical practices such as Shu-Mu point selection and region-specific treatment.[Conclusion]As a crucial component of meridian theory,the pathway of Qi theory has made significant strides in research of conceptualization,semantics and anatomical delineation.Further exploration is warranted to enhance its guidance in clinical applications.
3.Research on the Diagnostic Criteria for Dampness Syndrome Based on Consensus Method
Qian LI ; Wenzhen WU ; Zhixuan AI ; Lilei ZHOU ; Shujun LIU ; Xiaobo YANG
World Science and Technology-Modernization of Traditional Chinese Medicine 2024;26(6):1660-1667
Objective To establish diagnostic criteria for dampness syndrome through scientific and normative research methods.Methods The basis for syndrome differentiation of dampness syndrome was comprehensively integrated through literature research and structured tools,and in-depth investigation was carried out on the connotation and extension of dampness syndrome,judgment basis and criteria construction through questionnaire surveys and consensus conference method.Results Thirty-six items for syndrome differentiation of dampness syndrome were obtained through literature research.Through the questionnaire surveys,some experts suggested that the diagnosis mode of dampness syndrome should be in line with the clinical practice requirements.Accordingly,we were deep in thought about the key issue of"how to establish accurate diagnostic criteria".After in-depth investigation,we found that the dampness syndrome had specific and sensitive indicators.And 11 specific and 19 sensitive indicators were determined.Furthermore,according to the experts'suggestions,the specific indicators were classified into three categories based on dampness characteristics.Meanwhile,we investigated the diagnosis attributes of Chinese medicine syndromes and summarized them into four corresponding modes.Based on this,specificity mode and similarity/consistency mode should be adopted for diagnostic criteria for dampness syndrome.In addition,the judgment form in accord with the diagnostic attributes of dampness syndrome was determined.Conclusion This diagnostic criteria can provide a basis for the clinical diagnosis of dampness syndrome.Besides,this study explored the diagnostic attributes of Chinese medicine syndromes,which could provide reference for the development of other Chinese medicine syndrome criteria.
4.Establishment of Bacterial Endotoxin Test Method for Peramivir Hydrate and Sodium Chloride Injection
Shiqin QIAO ; Zhuye SUN ; Weigang LI ; Lilei WU
China Pharmacy 2015;(27):3853-3854
OBJECTIVE:To establish a method for bacteria1 endotoxin test for Peramivir hydrate and sodium chloride injec-tion. METHODS:Maximum non-interference concentration of the sample with different batohes were used for interference test. was determined by interference test according to endotoxin gel method stated in Chinese Pharmacopiea (2010 edition)and bacterial en-edotoxintest by tachypleus amebocyte lysate from 2 manufact urers. RESULTS:The interference on bacterial endotoxin test could be excluded when the sample was diluted to 2.5 mg/ml and the limit of bacterial endotoxins was 0.5 EU/ml. CONCLUSIONS:The established method can be used to detect the bacterial endotoxin of Peramivir hydrate and sodium chloride injection.

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