Objective To explore the active monitoring strategies for hypoglycemia in hospitalized dia-betic patients,as well as their clinical symptom characteristics and influencing factors.Methods A retrospec-tive search was conducted on all inpatients in a tertiary hospital in 2023.The hospital's electronic medical re-cord system was manually retrieved through the inpatient numbers of the patients.Adult inpatients with dia-betes who experienced hypoglycemia were included as the research subjects,and the general conditions and possible hypoglycemia-related risk factors were collected.Embed the hypoglycemic electronic trigger program in China Hospital Pharmacovigilance System(CHPS),reviewed the original medical records of patients with positive trigger triggering,and calculated the positive predictive value(PPV).Searched for the number of hy-poglycemic adverse reaction cases voluntarily reported by this hospital during the same period from National Adverse Reaction Monitoring System and compared with the actual number of hypoglycemic cases discovered.Patients with suspected drug-induced hypoglycemia were divided into the symptomatic group and the asymp-tomatic group based on whether they presented hypoglycemia-related symptoms.Multivariate logistic regres-sion analysis was applied to analyze the influencing factors.Results A total of 1 001 adult hospitalized diabet-ic patients with hypoglycemia were included in the study.Among them,725 cases were suspected of drug-in-duced hypoglycemia,and 495 cases were suspected of hypoglycemia caused by drug interactions.After manual review,131 cases of drug-induced hypoglycemia patients had clinical symptoms,and hypoglycemic adverse re-action events should be reported,PPV of this trigger for symptomatic hypoglycemia was 18.1%(131/725).However,the number of hypoglycemic adverse reactions spontaneously reported through National Adverse Reaction Monitoring System by this hospital during the same period was 4 cases,and the reporting rate was only 3.1%(4/131).Multivariate logistic regression analysis showed that aging and grade 2 hypoglycemia were risk factors for the occurrence of related symptoms in patients with suspected drug-induced hypoglycemia(P<0.05),while surgery,type 2 glucosuria,unclassified diabetes,and the use of insulin secretagogues were protective factors(P<0.05).Conclusion Drug-induced hypoglycemia dominates among hospitalized diabetic patients,and age,hypoglycemia grade,inpatient department using insulin secretagogues,diabetes diagnosis and classification are closely related to the occurrence of clinical hypoglycemia-related symptoms.Active monito-ring through CHPS can effectively increase the detection rate and reporting rate of hypoglycemic adverse e-vents in hospitalized diabetic patients.

Malnutrition is one of the main complications for gastric cancer patients, with an incidence rate as high as 65% to 85%, severely affecting their quality of life and survival rate. This issue is particularly prominent during out-of-hospital treatment, as patients often lack nutritional knowledge and do not receive continuous nutritional management. Therefore, ensuring that patients continue to receive effective nutritional management after discharge is crucial. This study explored three primary models of nutritional management for gastric cancer patients after discharge: the multidisciplinary team collaboration model, three-level nutritional management model, and the Internet+ model. It also analyzed the shortcomings and challenges these models face in practice, with the aim of providing a reference for clinical work.

Malnutrition is one of the main complications for gastric cancer patients, with an incidence rate as high as 65% to 85%, severely affecting their quality of life and survival rate. This issue is particularly prominent during out-of-hospital treatment, as patients often lack nutritional knowledge and do not receive continuous nutritional management. Therefore, ensuring that patients continue to receive effective nutritional management after discharge is crucial. This study explored three primary models of nutritional management for gastric cancer patients after discharge: the multidisciplinary team collaboration model, three-level nutritional management model, and the Internet+ model. It also analyzed the shortcomings and challenges these models face in practice, with the aim of providing a reference for clinical work.

This article reviews the concept and current situation, assessment tools, influencing factors, intervention measures, shortcomings, and prospects of sense of coherence in cancer patients, so as to provide reference and direction for subsequent research on sense of coherence in cancer patients.

Objective To survey the current demand of medical record information for at all levels of nursing staff in grade three class A hospital. Methods Questionnaire for demand of medical record information was designed, then nursing staff at grade three general hospital were investigated, in order to understand the need of medical record information for at all levels of nursing staff, and analyze the characteristics of need. Results Different occupational title had different demand on writing thesis, research proposal and knowledge accumulation and update when they referred to medical record information (χ2 =37. 260, 48. 948, 19. 399;P<0. 01). At the aspect of referring to the span of medical records information, all level nurses had statistical difference at the medical records information between in 1 year and 10 years (χ2 =29. 669, 25. 963;P<0. 01). There was no statistical significance on the demand of medical record specific information among all level nurses (P>0. 05). Conclusions The demand of different level nursing staff should be considerate to improve the model of medical records service and provide corresponding services to enhance the utilization of medical records information among nursing staffs.

Objective To investigate the variabihty of absolute and relative biochemical concenstrations at different repetition time(TR) in quantifying normal brain by single voxel proton MR spectroscopy.Methods Thirty normal volunteers signed informed consent were recruited for the study.Short echo time(TE=35 ms)single voxel spectroscopy of the left parieto-occipital white matter were performed on a 1.5 T MR scanner by using point-resolved selective spectroscopy(PRESS)sequence.Two spectra were obtained using the same voxel placement and acquisition parameters but at different TRs:first at TR=1500 ms then at TR=5000 ms.Raw data of spectra were processed on a commercial software Liinear combination model(LCModel)normalized to spectral date obtained from a reference phantom of known metabolite quantities.Measured metabohtes included total creatine(tCr,creatine and phosphocreatine),glutamate(Glu),myo-inositol(mI),N-acytalaspartate(NAA),glycerophosphorylcholine(GPC),glutamate and glutamine(Glx).The t test was performed by using SPSS 11.5 for windows.Results Both the absolute and relative concentrations of normal white matter were significanth different between spectra obtafined at TR=1500 ms and that at TR=5000 ms(P＜0.05).The absolute concentrations(mmol/L)at TR=1500 ms were tCr,3.0±0.2;Glu,4.4±0.7;ml,3.0±0.3;NAA,5.0±0.4;GPC,1.1±0.1:Glx,5.9±0.6;compared to concentration at TR=5000 ms,tCr,4.2±0.4;Gitu,5.3±0.5;mI.3.7±0.5;NAA,6.7±0.7;GPC,1.4±0.1;Glx,6.6±0.6;respectively.The concentrations relatively to tCr at TR=1500 ms,were Glu,1.47±0.27;mI,1.00±0.11;NAA,1.69±0.17;GPC,0.36±0.05;Glx,1.95±0.22;and relative concentrations at TR=5000 ms were Glu,1.25±0.12;mI,0.89±0.09;NAA,1.60±0.16;GPC,0.33±0.04;Glx,1.58±0.17;respectively.Conclusion Proton MR spectroscopy can accurately quantify absolute and relative concentrations of brain metabolites.Metabolites concentrations may be significant underestimated when using shorter repetition time in short TE spectroscopic study.

Objective To evaluate the diagnostic value of CT guided percutaneous transthoracic core needle biopsy (TCNB). Methods CT guided TCNB were performed on 121 cases who had suffered from pulmonary diseases. Cook QC 18G, 19G, or 20 gauge needles were used. The diameter of the pulmonary lesions was ranged from 0.8cm to 9.5cm, mean (3.4?1.9)cm. Postbiopsy complications were observed by routine CT scan. Results According to the Westcott's method, the final diagnosis of 86 cases of malignancy and 35 cases of benignancy had been established. Seventy nine malignant and 32 benign ones could be accurately diagnosed by TCNB. The overall diagnostic accuracy was 91.7%(111/121). The sensitivity of TCNB in the malignancy was 91.9%(79/86) with 7 cases of false negative, and the specificity was 100%. Seventy cases of malignancy could be made definitely. The sensitivity of benignancy was 91.4%(32/35). Complication of pneumothorax in 22 cases (18.2%) and pulmonary hemorrhage in 19 cases (15.7%) resolving spontaneously. Conclusions CT guided TCNB is a safe, reliable method with high accuracy in diagnosis and less complications, especially for non lung cancer malignancy and benign lesions.