1.Assessment Of Depression And Anxiety In Neurological Disorder Patients And Their Relationship With Quality Of Life
Priscilla Das ; Nyi Nyi Naing ; Nadiah Wan-Arfah ; KON Noorjan ; Yee Cheng Kueh ; Kantha Rasalingam
Malaysian Journal of Public Health Medicine 2021;21(2):112-123
This study aimed to assess the association between major depressive disorder, anxiety disorders and the quality of life of neurological disorder (brain tumour/brain disorder) patients. The study was conducted at Kuala Lumpur Hospital, Malaysia, a tertiary referral center hospital for neurological disorder patients. The cross-sectional study design was applied. The Mini-International Neuropsychiatric Interview and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire were used in the study.A total of 100 neurological disorder patients were included in the study. The study found that the Major depressive disorder correlated with almost all domains of the quality of life, except the nausea and vomiting scores. Logistic regression showed that emotional functioning and pain were related to major depressive disorder. Different anxiety disorders also correlated with quality of life in specific domains. The leading anxiety disorders that associated mostly with quality-of-life scales were post-traumatic stress disorder, panic disorder lifetime and current, panic disorder with agoraphobia, obsessive compulsive disorder, anxiety disorder and with agoraphobia current and social phobia current (p < 0.05). There is a significant relationship between psychiatric disorders and quality of life neurological disorder patients. Therefore treatment along with psychiatricintervention should be implemented to improve the overall curability of the neurological disorder patients.
2.A rare case of paediatric pontine Glioblastoma presenting as a cerebellopontine angle otogenic abscess
Kantha Rasalingam ; Jafri Malin Abdullah ; Zamzuri Idris ; Hillol Kanti Pal ; Nasser Wahab ; Effat Omar ; Salma@Win Mar
Malaysian Journal of Medical Sciences 2008;15(1):44-48
We describe rare case of a 9-year old boy who presented with a two- week history of right ear discharge and mild fever. Contrast enhanced CT scan of the brain
showed a lesion in the right cerebellopontine angle with mild enhancement mimicking early abscess formation. Involvement of the mastoid air cells pointing
towards a radiological diagnosis of mastoiditis reinforced the diagnosis of an abscess. A magnetic resonance imaging (MRI) was planned for the patient but his
conscious level deteriorated and patient slipped into coma warranting immediate surgical intervention. Intraoperatively, about 90% of the tumour was removed
and the appearance of the tumour resembled that of an acoustic schwannoma but histopathology confirmed the diagnosis of a glioblastoma multiforme (GBM). MRI
done post operatively showed lesion in the pons confirming the diagnosis of an exophytic pontine glioblastoma multiforme.


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