1.Oropharyngeal Synovial Sarcoma: A Case Report
Mohammad Zakwan Mohamed Zin ; Mohammad Zakwan Mohamed Zin ; Avatar Singh Mohan Singh ; Shiraz Qamil Muhammad Abdul Kadar ; Suhana Abdul Rahim ; Kannivanen Arasu ; Nur Eliana Ahmad Termizi ; Hui Heng Chua ; Norsyamira Aida Mohamad Umbaik ; Irfan Mohamad
Archives of Orofacial Sciences 2025;20(1):53-58
Oropharyngeal Synovial Sarcoma: A Case Report
Synovial sarcoma is a rare and aggressive type of sarcoma that develops from mesenchymal cells and
accounts for around 8% to 10% of all cases of soft tissue sarcoma. The presence of synovial sarcoma
in the head-and-neck region is characterised by aggressive behaviour and a generally unfavourable
prognosis. Understanding the various manifestations of synovial sarcoma, particularly uncommon
locations like the oropharynx, significantly improves patient outcomes by facilitating early diagnosis and
prompt management. We report a case of a 57-year-old Malay woman who presented with a two-month
history of sore throat and odynophagia, complicated with partial airway obstruction. She underwent
endoscopic excision of the right oropharyngeal tumour via transoral approach, and the histopathological
examination revealed monophasic synovial sarcoma. The surgical management, histopathological
characteristics, and rarity of the disease are discussed.
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