Integration of sports and medicine focuses on using exercise to prevent chronic diseases and enhance physical health.Frailty, a common syndrome in the elderly, has significant impacts on various aspects of their well-being.China currently lacks clear and unified recommendations for physical and health integration interventions for frailty.This consensus aims to gather the latest evidence and clinical experiences, both domestically and internationally, to minimize functional impairments in the elderly, slow down frailty progression, and improve quality of life through integrated strategies.Ultimately, the goal is to ensure the health and well-being of the elderly population.

Integration of sports and medicine focuses on using exercise to prevent chronic diseases and enhance physical health.Frailty, a common syndrome in the elderly, has significant impacts on various aspects of their well-being.China currently lacks clear and unified recommendations for physical and health integration interventions for frailty.This consensus aims to gather the latest evidence and clinical experiences, both domestically and internationally, to minimize functional impairments in the elderly, slow down frailty progression, and improve quality of life through integrated strategies.Ultimately, the goal is to ensure the health and well-being of the elderly population.

AIM and METHODS: Rat myocardial mRNA was extracted and mitochondrial sarcomeric creatine kinase (sMiMi-CK) was used as labled probed in vitro myocardial ischemia/reperfusion rats. Northern blot was performed to determine the changes of sMiMi-CK mRNA in different periods of ischemia/reperfusion and the protective effect of phosphocreatine (PCr).RESULTS:During early ischemial (10 min) mRNA was decreased about 18 24%. After reperfusion mRNA decreased again. PCr effectively prevented the decrease of mRNA expression of sMiMi-CK. CONCLUSION:The results indicated that PCr may possess protective effect on anoxic and reoxygenated myocardium.