Objective To investigate the effect of comprehensive hyperbaric oxygen (HBO) on 280 cases of persistent vegetative state (PVS) and the importance of radiological examination in the diagnosis of PVS.Methods Comprehensive HBO therapy combined with blood magnetization therapy and drugs treatment were administered to 280 patients with PVS.Results In a total of 280 PVS cases,85 were cured,accounting for 30.4%;148 cases improved,accounting for 52.8%;43 cases,accounting for 15.2% remained in the persistent vegetative state,but with overall improvement;4 cases died,accounting for 1.6%.Abnormal signs and symptoms could be found via cerebral CT in the 280 cases of PVS.Atrophy of mesencephalon and brain stem were revealed through MRI examination in 76 cases of PVS.Single photon emission computed tomography (SPECT) found that blood perfusion in different cerebral regions decreased in 32 cases of PVS.Following comprehensive HBO therapy coupled with other treatment for 20 - 50 times patients recovered from PVS to various degrees and radiological examinations revealed that signs and symptoms improved significantly.Conclusions The therapeutic effect of comprehensive HBO couple with other treatment on PVS was satisfactory.Cerebral SPECT imaging could be complementary to CT and MRI and it could be used as an index to forecast the therapeutic effect of comprehensive HBO treatment and prognosis of PVS.

Objective To investigate the effect of comprehensive hyperbaric oxygen (HBO) on 280 cases of persistent vegetative state (PVS) and the importance of radiological examination in the diagnosis of PVS.Methods Comprehensive HBO therapy combined with blood magnetization therapy and drugs treatment were administered to 280 patients with PVS.Results In a total of 280 PVS cases,85 were cured,accounting for 30.4%;148 cases improved,accounting for 52.8%;43 cases,accounting for 15.2% remained in the persistent vegetative state,but with overall improvement;4 cases died,accounting for 1.6%.Abnormal signs and symptoms could be found via cerebral CT in the 280 cases of PVS.Atrophy of mesencephalon and brain stem were revealed through MRI examination in 76 cases of PVS.Single photon emission computed tomography (SPECT) found that blood perfusion in different cerebral regions decreased in 32 cases of PVS.Following comprehensive HBO therapy coupled with other treatment for 20 - 50 times patients recovered from PVS to various degrees and radiological examinations revealed that signs and symptoms improved significantly.Conclusions The therapeutic effect of comprehensive HBO couple with other treatment on PVS was satisfactory.Cerebral SPECT imaging could be complementary to CT and MRI and it could be used as an index to forecast the therapeutic effect of comprehensive HBO treatment and prognosis of PVS.

AIM: To study the protective effects of n on -mitogenic human fibroblast growth factor (nm-haFGF) on cardiomyocytes injured b y reactive oxygen free radicals. METHODS: The cardiomyocytes were isolated from neonatal SD mouse by trypsin digestion. The cardiomyocytes injury model was established by expos ing the cells to hydrogen peroxide (H 2O 2), and the injury status in cardiomy ocytes were evaluated by examining the cellular viability, measuring cell apopto sis and observing the change of cellular morphology. nm-haFGF was added to the c ulture medium, and the changes of cellular viability, superoxide dismutase (SOD) , malondialdehyde (MDA) and celluar apoptosis were observed. RESULTS: A dose-dependence relation between the concentration of H 2O 2 and the cardiomyocytes injury was observed. 10-80 ?g/L nm-haFGF dose -dependently increased cardiomyocyte viability and the general SOD activity, as well as decreased the content of MDA and the quantity of cardiomyocyte apoptosis . CONCLUSION: The higher the concentration of H 2O 2, the mor e serious the cardiomyocyte injury. nm-haFGF may have a good protective effects on cardiomyocytes treated with H 2O 2.