The world has now rediscovered the value of traditional medicine. Much traditional medicine in South-East Asian countries originated from the medicines of ancient China, and developed independently within those individual countries. As a measure toward information exchange and communication among these countries, the World Health Organization's Western Pacific Regional Office (WHO-WPRO) has published its International Standard Terminologies (IST) for use globally. While domestically in Japan, Kampo is now taught as a regular subject in all medical schools. In this light, there is significant meaning to holding conference with the purpose of understanding the current status of Japanese Kampo around the world, and considering the best ways to disseminate Kampo information globally. The International Conference of Kampo Medicine (provisional title) has been held thus far a total of three times, to address the current status of Japanese Kampo, Japanese Kampo issues from global point of view, as well as the current status of traditional medicine in China and Korea also originating from the ancient Chinese medicine. The conference was entitled &lsquoWhy Kampo? Why Now? Why Me?—The reason why foreign medical doctors worldwide choose Japanese Kampo, and the situation or development of Kampo medicine in their own countries”, in which foreign doctors in Japan, medical students, and leading Kampo medical practitioners were invited to give lectures, which were followed by free discussions by all participants.
Medicine, Kampo ; Medicine ; seconds ; Japanese language ; Conferences

View ; Japanese language ; Acupuncture

From ancient times, the crude drug rhubarb (Da-huang in Chinese, Daio in Japanese) has been processed using liquor in various ways in China. There are mainly three ways of processing it ; liquor-soaking, liquor-dipping and liquor-frying. Today, the liquor-fried rhubarb, appropriately named ‘liquor rhubarb’, is widely used. But it is not clear why use of the rhubarb processed with liquor began. Thus, we researched ancient literature published after the Jin and Yuan dynasties, when medical treatment was done based on the theories. We found that the ‘liquor-soaked rhubarb’ was used as a depurative, while the ‘liquor-dipped rhubarb’ was used as a purgative or a digestive. ‘Liquor-fried rhubarb’ use began after the Ming dynasty, and its medicinal effect was expected to be the same as the two processed rhubarbs of earlier periods.
distilled alcoholic beverage ; Rhubarb ; Today ; dalton ; Japanese language

We investigated the clinical efficacy of concomitant Kampo treatments, expected to have immediate effect in improving outcomes with western drug therapies for Japanese cedar pollinosis. Twenty cases using shoseiryuto, considered a first-line drug for allergic rhinitis, were studied. The resultant efficacy rate was 45%. The efficacy rate for 24 cases using eppikajutsuto, by contrast, was 64%. The latter cases demonstrated far better therapeutic result than the former. In 7 cases using maoto + eppikajutsuto (as simplified daiseiryuto), another prescription we often use for serious illness, the resultant efficacy rate was 72%. Of these, the most favorable effect resulted in 16 cases using shoseiryuto + gokoto, which resulted in an efficacy rate of 87%. We had originally developed this prescription in order to improve the effectiveness of mao and sekko as anti-inflammatories. There were no cases where patients needed to be dosed with an oral steroid. The only notable event was one patient who complained of stomachache as an adverse drug reaction. In conclusion, we can say that the overall therapeutic outcome with 11 different Kampo medicines was extremely satisfactory: an efficacy rate of 83%. These marked improvements in clinical efficacy were made by using Kampo medicines together with a western drug used for the treatment of Japanese cedar pollinosis.
Medicine, Kampo ; Japanese language ; Clinical ; Therapeutic procedure ; Western Herbs and Botanicals

Japanese pharmacopoeia prescribes a crude drug, Uncaria hook, or the hook-like structures of Uncaria rhynchophylla (Miq.) Jacks, U. sinensis (Oliv.) Havil., and U. macrophylla Wall., while Chinese pharmacopoeia prescribes the hooks with attached stems of above3species, in addition to2other species of Uncaria hook; U. hirsuta Havil. and U. sessilifructus Roxb (all in the Rubiaceae family). Our herbological study has found that the botanical origin was Uncaria rhynchophylla before the Ming Dynasty, and that the part used was not the hook itself, but the plant's bark till the early Ming Dynasty. Use of the hooks with stems began in the late Ming Dynasty. On the other hand, in Japan, the hooks themselves have been mainly collected from wild U. rhynchophylla plants growing in southern warm-temperate zone of Japan, for use in Kampo medicines. We considered this differing Japanese custom was influenced by the descriptions in the Ben Cao Gan Mu (1596)written in the Ming dynasty by Li Si Chen, which state that the hook itself had medicinally sharp power. And we conclude that use of Uncaria bark alone is reasonable for prescriptions which originated before the early Ming dynasty, such as chotosan.
Unit ; Chinese People ; Japanese language ; Within ; Hook

Objectives : The objective of this study is to develop a Japanese version of the Constitution in Chinese Medicine Questionnaire (CCMQ) in Chinese, which is comprised of 60 items with 9 sub-scales, and evaluate its reliability and validity. Methods : We conducted a survey of 130 participants in the Toyama area of Japan from Dec. 2005, to Feb. 2006. A test-retest method was used. Feasibility was evaluated by the response times to the questionnaire, and the response rates of the CCMQ items. Internal consistency within the sub-scales was assessed by Cronbach's α coefficient. Reproducibility was confirmed between the first and second occasions using weighted kappa and Spearman correlation. Lastly, criterion validity was evaluated by correlation between CCMQ and SF-36 sub-scales. Results : Response time was 8 minutes on average and its rate was nearly 100%. Internal consistency was achieved for each of the 9 sub-scales with a 0.65 to 0.79 α coefficient. Reproducibility ranged from 0.41 to 0.81 for the items, and from 0.79 to 0.88 for the sub-scales. Regarding the criterion validity, the “Gentleness type” sub-scale was positively correlated with SF-36 (0.46, P<0.001), while other 8 pathological constitutional types of the CCMQ were negatively correlated with SF-36 (-0.35 to -0.50, P<0.001) as expected. Conclusions : We developed a Japanese version of the CCMQ and found acceptable levels of reliability and validity using a survey of 130 subjects in Japan. This suggests that the CCMQ could be a useful tool in comparing the constitution profiles between Chinese and Japanese.
Japanese language ; Chinese People ; Questionnaires ; SF Brand of Topical Fluoride ; Medicine

Today ; Japanese language ; Language

Background: Little information has been collected on the prevalence of hypertension in different rural parts of Japan, using similar methods for sample selection and based on similar diagnostic criteria, and epidemiological studies are urgently needed in each Japanese rural county to determine the baseline against which future trends in risk factor levels can be assessed in order to be able to plan appropriate preventive strategies. Objective: To study the prevalence and its relationship to risk factors of hypertension without controlled drug treatment in rural populations. Materials and Methods: Three cross-sectional surveys were conducted in the Akita (north), Gifu (middle) and Fukuoka (south) regions during 2004-2005 using study subjects (n=1778) aged 40-79 years who participated in a health check-up program. Blood pressure was measured by a trained nurse. Information concerning their history of hypertension and lifestyle was obtained by self-administered questionnaires. Results: When comparing the three regions, the prevalence of hypertension (≥140/90 mmHg) without controlled drug treatment demonstrated a significant difference among males (16.8%, 22.1% and 12.7% in Akita, Gifu and Fukuoka, respectively; p<0.05). However, no significant difference was seen among females (14.4%, 16.0% and 16.5% in Akita, Gifu and Fukuoka, respectively). According to a multivariate logistic regression analysis for these two groups in each of the three regions, the odds ratio (OR) showed that obesity (body mass index≥25 kg/m2) was strongly associated with the Hypertensive (-) group among females in two regions (ORs of 2.32 for both Akita and Fukuoka). Physical inactivity (average daily physical activity energy expenditure<300 kcal), alcohol drinking (alcohol intake≥44 g/day and/or frequency of drinking≥5 days/week), cigarette smoking (Brinkman index≥400) and a stressful lifestyle were not significantly associated with the Hypertensive (-) group among these rural populations. Conclusions: Therefore, hypertension in females in rural Japan may be controlled by a reduction in body weight.
Hypertension induced by pregnancy ; Risk Factors ; Japanese language ; Prevalence aspects ; Three

Japanese language ; Medicine ; Mental association

;Small, dense low density lipoprotein (LDL) has been suggested to be highly atherogenic as a result of their low-binding affinity to LDL receptors, their prolonged plasma half-life and low resistance to oxidative stress. Although marine n-3 polyunsaturated fatty acids (PUFAs) have beneficial effects for the prevention of cardiovascular diseases, there is little information on detailed fatty acid composition in LDL particles. In the present study, LDL subfractions were isolated from the plasma of 45 clinically healthy Japanese women by density gradient ultracentrifugation using a light fraction of 1.025-1.034 g/ml (LDL-I), an intermediate fraction of 1.034-1.044 g/ml (LDL-II), and a dense fraction of 1.044-1.060 g/ml (LDL-III). A clear relationship between the frequency of fish intake and increases in plasma n-3 PUFAs was apparent. Although plasma n-3 PUFAs in women with small-sized LDL using non-denaturing gradient gel electrophoresis (GGE) did not show a significant difference, n-3 PUFAs and n-3 PUFAs/n-6 PUFAs in dense LDL-III subfraction increased in the small-sized LDL group using GGE, compared to those with buoyant LDL particles. The result of enriched n-3 PUFAs in dense LDL subfraction suggests that n-3 PUFAs may help prevent atherosclerosis in the arteries of Japanese women with small-sized LDL.
Low density lipoprotein cholesterol measurement ; Lower case en ; Human Females ; Japanese language ; Plasma