This is a report of 8-months progression of circulating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants in Brunei Darussalam from November 2021. Whole-genome sequencing (WGS) was performed on nearly 3,000 random local COVID-19 patients in samples with a cycle-threshold (CT) of less than 25. Phylogenetic analysis revealed that the Delta variant, particularly AY.24.1, was the predominant variant towards the end of 2021. The same variant was then completely superseded by the Omicron variants in mid-January 2022. During the early wave of Omicron variants, BA.2.3.19 and its paternal BA.2.3 were found to be the prominent sublineage until it was replaced by BA.5 lineages four months later, mainly BA.5.2 and BF.5. Further analysis revealed that AY.24.1 and BA.2.3.19 that was once a prevalent variant are predominantly observed in Brunei. Both variants can be differentiated by the presence of a particular mutation in the S gene that encodes the viral spike protein that is essential for host cell interaction. Brunei is continuously monitoring the circulating SARS-CoV-2 variants as part of its genomic surveillance following the World Health Organization (WHO) guidance for surveillance.

Introduction: Erosive tooth wear (ETW) is an emerging dental condition worldwide. However, most dental practitioners overlooked the early stages of the condition due to vague clinical appearance of tooth surface loss. Therefore, this study was aimed to determine the knowledge of ETW and treatment given amongst dental professionals in private clinics in Kuantan, Pahang. Method: Several private dental clinics in Kuantan, Pahang, involved in this cross-sectional study. Dental practitioners were volunteering to participate in this research. A validated self-administered questionnaire was distributed, and a descriptive analysis was conducted. Results: The overall response rate was 75%. Results revealed that most participants obtained a structured education on ETW (79.2%). Through continuous dental education, about half of the participants learnt further. All participants agreed that carbonated drink caused ETW, and most reported that gastroesophageal reflux diseases and pickles had related to the ETW. The majority of participants favoured case note (79%) with regards to ETW records. Nevertheless, 40.9% and 36.4% are recorded at the tooth surface and individual level, respectively. Surprisingly, 79% of them did not know about special scores when assessing ETW. Most participants prefer to give instruction on oral hygiene and diet counselling as preventive measures, but the use of fluoride was not given priority. 77% have not ever referred the case to a dental specialist and preferred to treat the patient on their own. Conclusion: ETW knowledge among recruited PDPs is adequate; however, no specific indices were used for ETW scoring and insufficient treatment strategies..