1.Effect of Extracorporeal Shock Wave Therapy on Post-Laminectomy Lumbar Epidural Fibrosis
Usama M. RASHAD ; Marwa Hany ABOUSENNA ; Amr K. ELSAMMAN ; Nagwa Ibrahim REHAB
Annals of Rehabilitation Medicine 2025;49(2):81-90
Objective:
To investigate the effectiveness of radial extracorporeal shock wave therapy (rESWT) on pain, lumbar range of motion (ROM) and F-wave minimal latency and F-chronodispersion in patients with post laminectomy epidural fibrosis.
Methods:
Sixty patients complaining of low back pain and sciatica secondary to lumbar post laminectomy epidural fibrosis were allocated to one of the two equal groups (study and control groups). Pain intensity, lumbar ROM, and F-wave latency and F-chronodispersion were assessed pre- and posttreatment using visual analogue scale (VAS), Back ROM II device, and Neuro-MEP-Micro electromyography device, respectively.
Results:
Posttreatment mean values showed statistically significant decrease in VAS mean scores in both groups, with more significant decrease posttreatment in favor of the study group. There was statistically significant increase in all lumbar ROM mean scores and statistically significant decrease in F-minimal latency and F-chronodispersion for both peroneal and tibial nerves in the study group only posttreatment. Also, the results showed that significant positive moderate correlation between VAS scores and F-chronodispersion for peroneal nerve, strong negative correlation between right side bending scores and F-wave minimal latency for peroneal nerve and moderate negative correlation between left side bending scores and F-wave minimal latency for peroneal nerve after treatment.
Conclusion
It was concluded that rESWT is a new and convenient modality, that would be beneficial if added to the conventional physical therapy protocols in managing patients with lumbar post-laminectomy epidural fibrosis.
2.Effect of Extracorporeal Shock Wave Therapy on Post-Laminectomy Lumbar Epidural Fibrosis
Usama M. RASHAD ; Marwa Hany ABOUSENNA ; Amr K. ELSAMMAN ; Nagwa Ibrahim REHAB
Annals of Rehabilitation Medicine 2025;49(2):81-90
Objective:
To investigate the effectiveness of radial extracorporeal shock wave therapy (rESWT) on pain, lumbar range of motion (ROM) and F-wave minimal latency and F-chronodispersion in patients with post laminectomy epidural fibrosis.
Methods:
Sixty patients complaining of low back pain and sciatica secondary to lumbar post laminectomy epidural fibrosis were allocated to one of the two equal groups (study and control groups). Pain intensity, lumbar ROM, and F-wave latency and F-chronodispersion were assessed pre- and posttreatment using visual analogue scale (VAS), Back ROM II device, and Neuro-MEP-Micro electromyography device, respectively.
Results:
Posttreatment mean values showed statistically significant decrease in VAS mean scores in both groups, with more significant decrease posttreatment in favor of the study group. There was statistically significant increase in all lumbar ROM mean scores and statistically significant decrease in F-minimal latency and F-chronodispersion for both peroneal and tibial nerves in the study group only posttreatment. Also, the results showed that significant positive moderate correlation between VAS scores and F-chronodispersion for peroneal nerve, strong negative correlation between right side bending scores and F-wave minimal latency for peroneal nerve and moderate negative correlation between left side bending scores and F-wave minimal latency for peroneal nerve after treatment.
Conclusion
It was concluded that rESWT is a new and convenient modality, that would be beneficial if added to the conventional physical therapy protocols in managing patients with lumbar post-laminectomy epidural fibrosis.
3.Effect of Extracorporeal Shock Wave Therapy on Post-Laminectomy Lumbar Epidural Fibrosis
Usama M. RASHAD ; Marwa Hany ABOUSENNA ; Amr K. ELSAMMAN ; Nagwa Ibrahim REHAB
Annals of Rehabilitation Medicine 2025;49(2):81-90
Objective:
To investigate the effectiveness of radial extracorporeal shock wave therapy (rESWT) on pain, lumbar range of motion (ROM) and F-wave minimal latency and F-chronodispersion in patients with post laminectomy epidural fibrosis.
Methods:
Sixty patients complaining of low back pain and sciatica secondary to lumbar post laminectomy epidural fibrosis were allocated to one of the two equal groups (study and control groups). Pain intensity, lumbar ROM, and F-wave latency and F-chronodispersion were assessed pre- and posttreatment using visual analogue scale (VAS), Back ROM II device, and Neuro-MEP-Micro electromyography device, respectively.
Results:
Posttreatment mean values showed statistically significant decrease in VAS mean scores in both groups, with more significant decrease posttreatment in favor of the study group. There was statistically significant increase in all lumbar ROM mean scores and statistically significant decrease in F-minimal latency and F-chronodispersion for both peroneal and tibial nerves in the study group only posttreatment. Also, the results showed that significant positive moderate correlation between VAS scores and F-chronodispersion for peroneal nerve, strong negative correlation between right side bending scores and F-wave minimal latency for peroneal nerve and moderate negative correlation between left side bending scores and F-wave minimal latency for peroneal nerve after treatment.
Conclusion
It was concluded that rESWT is a new and convenient modality, that would be beneficial if added to the conventional physical therapy protocols in managing patients with lumbar post-laminectomy epidural fibrosis.
4.Tenecteplase Versus Alteplase in Medium Vessel Occlusion Ischemic Stroke: A Secondary Analysis of the Alteplase Compared to Tenecteplase Randomized Trial
Fouzi BALA ; Nishita SINGH ; Katrina IGNACIO ; Ibrahim ALHABLI ; Ayoola ADEMOLA ; Anas ALROHIMI ; Houman KHOSRAVANI ; Aleksander TKACH ; Luciana CATANESE ; Dariush DOWLATSHAHI ; Thalia FIELD ; Gary HUNTER ; Faysal BENALI ; MacKenzie HORN ; Andrew DEMCHUK ; Michael HILL ; Tolulope SAJOBI ; Brian BUCK ; Richard SWARTZ ; Mohammed ALMEKHLAFI ; Bijoy K. MENON
Journal of Stroke 2024;26(2):280-289
Background:
and Purpose The safety and efficacy of tenecteplase in patients with ischemic stroke due to medium vessel occlusion (MeVO) are not well studied. We aimed to compare tenecteplase with alteplase in stroke due to MeVO.
Methods:
Patients with baseline M2-middle cerebral artery (MCA), M3/M4-MCA, P2/P3/P4-posterior cerebral artery (PCA), A2/A3/A4-anterior cerebral artery (ACA) occlusions from the Alteplase Compared to Tenecteplase (AcT) trial were included. Primary outcome was the proportion of 90-day modified Rankin Scale (mRS) 0–1. Secondary outcomes were 90-day mRS 0–2, ordinal mRS, mortality, quality of life measures (EuroQol 5-Dimension 5-Level, EuroQol visual analog scale), and symptomatic intracerebral hemorrhage (sICH). Initial and final successful reperfusion were reported in patients undergoing endovascular thrombectomy (EVT).
Results:
Among 1,558 patients with available baseline computed tomography angiography; 455 (29.2%) had MeVO of which 27.5% (125/455) were proximal M2; 16.3% (74/455) were distal M2; 35.2% (160/455) were M3/M4; 7.5% (34/455) were A2/A3/A4; and 13.6% (62/455) were P2/P3/P4 occlusions. EVT was performed in 87/455 (19.1%) patients. mRS 0–1 at 90 days was achieved in 37.9% in the tenecteplase versus 34.7% in the alteplase group (adjusted risk ratio [aRR] 1.07; 95% confidence interval [CI] 0.91–1.25). Rates of 90-day mRS 0–2, sICH, and mortality were similar in both groups. No statistical difference was noted in initial successful reperfusion rates (13.0% vs. 7.5%) among the 87 patients who underwent endovascular thrombectomy. However, final successful reperfusion was higher in the tenecteplase group (71.7% vs. 60.0%, aRR 1.29, 95% CI 1.04–1.61).
Conclusion
Intravenous tenecteplase had comparable safety, functional outcomes and quality of life compared to intravenous alteplase among patients with MeVO. Among those treated with EVT, tenecteplase was associated with higher successful reperfusion rates than alteplase.
5.The Osseous Pathology of Purpura Fulminans in a TwoYear-Old Child: A Case Report
Mohd-Razali S ; Ahmad-Affandi K ; Ibrahim S ; Abdul-Rashid AH ; Abdul-Shukor N
Malaysian Orthopaedic Journal 2023;17(No.1):180-183
Purpura fulminans (PF) is a severe clinical manifestation of
Neisseria meningitides infection that is associated with high
mortality rates in children. Survivors are frequently left with
debilitating musculoskeletal sequelae. There is a paucity of
reports on the musculoskeletal pathology of purpura
fulminans. We report on a 2-year-old boy with purpura
fulminans due to meningococcemia. The child developed
distal gangrene in both the upper and lower limbs.
Amputations were done for both lower limbs. Histological
examination of the amputated specimens showed an
inflammatory process and features of osteonecrosis. The
latest follow-up at the age of 6 years showed a right knee
valgus due to asymmetrical growth arrest of the proximal
tibia. PF and its complications are challenging to treat and
may require a multidisciplinary approach to improve
patient’s functional ability.
6.Transtubular Transoral Approach for Irreducible Ventral Craniovertebral Junction Compressive Pathologies: Surgical Technique and Outcome
Ariffin MH ; Mohd-Mahdi SN ; Baharudin A ; M.Tamil A ; Abdul-Rhani S ; Ibrahim K ; Ng BW ; Tan JA
Malaysian Orthopaedic Journal 2023;17(No.2):35-42
Introduction: To investigate the use of a tubular retractor to
provide access to the craniovertebral junction (CVJ) sparing
the soft palate with the aim of reducing complications
associated with traditional transoral approach but yet
allowing adequate decompression of the CVJ.
Materials and methods: Twelve consecutive patients with
severe myelopathy (JOA-score less than 11) from ventral
CVJ compression were operated between 2014-2020 using a
tubular retractor assisted transoral decompression.
Results: All patients improved neurologically statistically
(p=0.02). There were no posterior pharynx wound infections
or rhinolalia. There was one case with incomplete removal of
the lateral wall of odontoid and one incidental durotomy.
Conclusions: A Tubular retractor provides adequate access
for decompression of the ventral compression of CVJ. As the
tubular retractor pushed away the uvula, soft palate and
pillars of the tonsils as it docked on the posterior pharyngeal
wall, the traditional complications associated with traditional
transoral procedures is completely avoided.
7.Poverty related diseases amongst Malaysia’s low-income community: a review
Abu Bakar, N. ; Sahimin, N. ; Lim, Y.A.L. ; Ibrahim, K. ; Mohd Zain, S.N.
Tropical Biomedicine 2023;40(No.1):65-75
Poverty, as proven by several studies, is a driving force behind poor health and hygiene practices.
This review attempts to outline common communicable and non-communicable diseases that
disproportionately affect Malaysia’s 2.91 million low-income households. The current study also looks
into the government’s housing and healthcare programmes for this demographic to improve their
health and well-being. The initial examination yielded incredibly little research on this marginalised
community, with event reporting typically generalised to the Malaysian community as a whole rather
than analysing disease incidences based on household income, which would better reflect povertydriven diseases. As a result, there is an acute need for more accurate information on the epidemiology
of diseases among the poor in order to address this public health issue and provide conclusions that
can drive policy designs.
8.EPOSTER • DRUG DISCOVERY AND DEVELOPMENT
Marwan Ibrahim ; Olivier D LaFlamme ; Turgay Akay ; Julia Barczuk ; Wioletta Rozpedek-Kaminska ; Grzegorz Galita ; Natalia Siwecka ; Ireneusz Majsterek ; Sharmni Vishnu K. ; Thin Thin Wi ; Saint Nway Aye ; Arun Kumar ; Grace Devadason ; Fatin Aqilah Binti Ishak ; Goh Jia Shen ; Dhaniya A/P Subramaniam ; Hiew Ke Wei ; Hong Yan Ren ; Sivalingam Nalliah ; Nikitha Lalindri Mareena Senaratne ; Chong Chun Wie ; Divya Gopinath ; Pang Yi Xuan ; Mohamed Ismath Fathima Fahumida ; Muhammad Imran Bin Al Nazir Hussain ; Nethmi Thathsarani Jayathilake ; Sujata Khobragade ; Htoo Htoo Kyaw Soe ; Soe Moe ; Mila Nu Nu Htay ; Rosamund Koo ; Tan Wai Yee ; Wong Zi Qin ; Lau Kai Yee ; Ali Haider Mohammed ; Ali Blebil ; Juman Dujaili ; Alicia Yu Tian Tan ; Cheryl Yan Yen Ng ; Ching Xin Ni ; Michelle Ng Yeen Tan ; Kokila A/P Thiagarajah ; Justin Jing Cherg Chong ; Yong Khai Pang ; Pei Wern Hue ; Raksaini Sivasubramaniam ; Fathimath Hadhima ; Jun Jean Ong ; Matthew Joseph Manavalan ; Reyna Rehan ; Tularama Naidu ; Hansi Amarasinghe ; Minosh Kumar ; Sdney Jia Eer Tew ; Yee Sin Chong ; Yi Ting Sim ; Qi Xuan Ng ; Wei Jin Wong ; Shaun Wen Huey Lee ; Ronald Fook Seng Lee ; Wei Ni Tay ; Yi Tan ; Wai Yew Yang ; Shu Hwa Ong ; Yee Siew Lim ; Siddique Abu Nowajish ; Zobaidul Amin ; Umajeyam Anbarasan ; Lim Kean Ghee ; John Pinto ; Quek Jia Hui ; Ching Xiu Wei ; Dominic Lim Tao Ran ; Philip George ; Chandramani Thuraisingham ; Tan Kok Joon ; Wong Zhi Hang ; Freya Tang Sin Wei ; Ho Ket Li ; Shu Shuen Yee ; Goon Month Lim ; Wen Tien Tan ; Sin Wei Tang
International e-Journal of Science, Medicine and Education 2022;16(Suppl1):21-37
9.Anxiety Reaction in Children During Cast Removal using Oscillating Saw versus Cast Shear - A Randomised, Prospective Trial
Mohamed-Zain NA ; Jamil K ; Penafort R ; Singh A ; Ibrahim S ; Abdul-Rashid AH
Malaysian Orthopaedic Journal 2021;15(No.2):122-128
Introduction: To compare the anxiety levels demonstrated
by children during cast removal procedure between
oscillating saw vs cast shear methods.
Material and methods: A randomised prospective study of
102 children (mean age 8.3 ± 3.5 years) with fractures
involving upper or lower limbs. Children undergoing
removal of cast were divided into 2 groups; either by an
oscillating saw or a cast cutting shear. The level of anxiety
was assessed by recording the heart rate with a portable
fingertip pulse oximeter before, during and after removal of
the cast. Objective assessment was performed by
documenting the fear level on Children’s Fear Scale (CFS).
Results: There was a significant increase in the heart rate of
children during cast removal while using the oscillating saw
compared to cast shear (p<0.05). The noise level produced
by the saw exceeded 80 dB (mean 103.3 dB). The fear level
was significantly lower in the cast shear group (p<0.05).
Conclusion: The noise produced by the oscillating saw was
associated with an increased anxiety level in children
undergoing cast removal. Cast shear is a simple and
inexpensive instrument that can be used for cast removal in
overly anxious children.
10.Subcapital Femoral Neck Tension Stress Fracture - A Rare Injury in A Child: A Case Report
Hayyun MF ; Jamil K ; Abd-Rashid AH ; Ibrahim S
Malaysian Orthopaedic Journal 2021;15(No.1):132-134
Femoral neck stress fractures are rare in children. To the best
of our knowledge, the tension type stress fracture has been
reported only twice in the English language literature. We
report on a five years follow-up of a 10-year-old boy with
this injury which was initially missed. The fracture healed
after screw fixation. We highlight the importance of
considering stress fracture as a differential diagnosis in a
child with chronic hip pain. A careful physical examination
and the appropriate imaging will avoid missing the
diagnosis.


Result Analysis
Print
Save
E-mail