Objective:To investigate the effectiveness of target energy-based oral nutritional support in the nutritional management of postoperative Crohn′s disease (CD) patients.Methods:A retrospective analysis was conducted. CD patients who underwent laparoscopic ileocecal and colonic resection and were managed with a conventional diet at the First Affiliated Hospital of Sun Yat-sen University from January 2020 to December 2020 were defined as conventional diet group. Another group of CD patients who underwent the same surgery from January 2021 to December 2021 and were managed with a target energy-based oral nutrition support model were defined as gradient diet group. The intestinal nutritional tolerance on the 4th day after surgery, body mass index (BMI) and serum albumin levels at 4 weeks after surgery, as well as prealbumin levels at 1st and 4th weeks after surgery, and length of hospital stay were compared between the two groups.Results:A total of 61 CD patients were included, with 31 in the conventional diet group and 30 in the gradient diet group. The gradient diet group showed significantly better intestinal nutritional tolerance, BMI, albumin levels at 4th weeks after surgery, as well as prealbumin levels at 1st and 4th weeks after surgery compared to the conventional diet group, with all differences being statistically significant ( P<0.01). The gradient diet group also had a significantly shorter length of hospital stay compared to the conventional diet group, with a statistically significant difference ( P<0.05) . Conclusions:The target energy-based oral nutrition support model for CD patients after surgery demonstrats better intestinal nutritional tolerance, more pronounced improvement in nutritional status, and more specific and feasible dietary guidance compared to the conventional diet management model. It also results in a shorter length of hospital stay for CD patients after surgery, suggesting its potential for clinical application and promotion.

Objective:To investigate the effectiveness of target energy-based oral nutritional support in the nutritional management of postoperative Crohn′s disease (CD) patients.Methods:A retrospective analysis was conducted. CD patients who underwent laparoscopic ileocecal and colonic resection and were managed with a conventional diet at the First Affiliated Hospital of Sun Yat-sen University from January 2020 to December 2020 were defined as conventional diet group. Another group of CD patients who underwent the same surgery from January 2021 to December 2021 and were managed with a target energy-based oral nutrition support model were defined as gradient diet group. The intestinal nutritional tolerance on the 4th day after surgery, body mass index (BMI) and serum albumin levels at 4 weeks after surgery, as well as prealbumin levels at 1st and 4th weeks after surgery, and length of hospital stay were compared between the two groups.Results:A total of 61 CD patients were included, with 31 in the conventional diet group and 30 in the gradient diet group. The gradient diet group showed significantly better intestinal nutritional tolerance, BMI, albumin levels at 4th weeks after surgery, as well as prealbumin levels at 1st and 4th weeks after surgery compared to the conventional diet group, with all differences being statistically significant ( P<0.01). The gradient diet group also had a significantly shorter length of hospital stay compared to the conventional diet group, with a statistically significant difference ( P<0.05) . Conclusions:The target energy-based oral nutrition support model for CD patients after surgery demonstrats better intestinal nutritional tolerance, more pronounced improvement in nutritional status, and more specific and feasible dietary guidance compared to the conventional diet management model. It also results in a shorter length of hospital stay for CD patients after surgery, suggesting its potential for clinical application and promotion.

Objective To analyze the related factors of influencing deep vein indwelling catheter dysfunction in hemodialysis patients.Methods A total of 37 cases with deep vein indwelling catheter in hemodialysis patients were selected.They were divided into patent group and blocked group according to the appearance of catheter dysfunction (hemodialysis blood flow less than three times 180 ml/min,adjustment of body position,inversion of tube connection during hemodialysis,requirement of thrombolytic therapy and so on) in 5 months.The common data and biochemical indicator were compared between two groups.Results Patent group had 28 cases,and blocked group had 9 cases.There was no significant difference in age,diabetes mellitus ratio,platelet,low density lipoprotein cholesterol and albumin between two groups (P ＞0.05).Hemoglobin in patent group was lower than that in blocked group [(90.1 ± 13.8) g/L vs.(108.3 ± 11.6) g/L],and there was significant difference(P＜ 0.05).Conclusion Hemoglobin is the correlated factor that effects deep vein indwelling catheter dysfunction after hemodialysis.