Objective To compare the therapeutic value of endoscopic ligation surgery and surgical hemorrhoidectomy for internal hemorrhoids.Methods This study was a retrospective study,selected 340 patients with internal hemorrhoids admitted to the hospital from February 2023 to April 2025.According to the treatment method,they were divided into two groups:160 patients who underwent surgical hemorrhoidectomy as the control group and 180 patients who underwent endoscopic ligation surgery as the observation group.The surgical related indicators of the two groups were compared to evaluate postoperative anal pain,detect serum inflammatory factors,anal function,anorectal motility indicators,anal stenosis degree before and after surgery,and statistically analyze the incidence of complications.Results The observation group had a shorter surgical time,less intraoperative bleeding,and lower treatment costs compared to the control group,with statistically significant differences(P<0.05).On the 1st and 7th day after the surgery,the pain visual analogue scale(VAS)scores of the observation group were significant lower than those of the control group,with statisticlly significant differences(P<0.05).One month after the surgery,the levels of serum inflammatory factors in the observation group were lower than those of the control group,with statisticlly significant differences(P<0.05).One month after the surgery,the score of the anal function Kelly scale in the observation group was higher than that of the control group,with statisticlly significant difference(P<0.05).One month after the surgery,there were obvious differences in the levels of anorectal dynamic indicators between the two groups(P<0.05).The incidence of complications and the rate of anal stenosis in the observation group were relatively lower(P<0.05).Conclusion Both endoscopic ligation surgery and surgical hemorrhoidectomy can be used in the treatment of internal hemorrhoids.However,compared with the latter,the former is more effective in improving the patient's serum inflammatory factors,anal function,and postoperative pain.It can also shorten the patient's operation time,reduce the intraoperative blood loss,and relieve the patient's economic burden.

Objective To compare the therapeutic value of endoscopic ligation surgery and surgical hemorrhoidectomy for internal hemorrhoids.Methods This study was a retrospective study,selected 340 patients with internal hemorrhoids admitted to the hospital from February 2023 to April 2025.According to the treatment method,they were divided into two groups:160 patients who underwent surgical hemorrhoidectomy as the control group and 180 patients who underwent endoscopic ligation surgery as the observation group.The surgical related indicators of the two groups were compared to evaluate postoperative anal pain,detect serum inflammatory factors,anal function,anorectal motility indicators,anal stenosis degree before and after surgery,and statistically analyze the incidence of complications.Results The observation group had a shorter surgical time,less intraoperative bleeding,and lower treatment costs compared to the control group,with statistically significant differences(P<0.05).On the 1st and 7th day after the surgery,the pain visual analogue scale(VAS)scores of the observation group were significant lower than those of the control group,with statisticlly significant differences(P<0.05).One month after the surgery,the levels of serum inflammatory factors in the observation group were lower than those of the control group,with statisticlly significant differences(P<0.05).One month after the surgery,the score of the anal function Kelly scale in the observation group was higher than that of the control group,with statisticlly significant difference(P<0.05).One month after the surgery,there were obvious differences in the levels of anorectal dynamic indicators between the two groups(P<0.05).The incidence of complications and the rate of anal stenosis in the observation group were relatively lower(P<0.05).Conclusion Both endoscopic ligation surgery and surgical hemorrhoidectomy can be used in the treatment of internal hemorrhoids.However,compared with the latter,the former is more effective in improving the patient's serum inflammatory factors,anal function,and postoperative pain.It can also shorten the patient's operation time,reduce the intraoperative blood loss,and relieve the patient's economic burden.

BACKGROUND:After different metal fixation materials areimplanted into the human body, peripheral tissue inflammatory response to varying degrees wil appear in the early stage. Poor biocompatibility of the corresponding materials wil lead to prolonged duration of inflammatory reaction.
OBJECTIVE:To investigate the inflammatory factor level changes and biocompatibility of cancelous bone screw fixation in treatment of unstable pelvic fractures.
METHODS:A total of 61 patients with unstable pelvic fractures were randomly divided into the observation group (29cases) and the control group (32 cases). The 29 patients in the observation group underwent cancelous bone screw fixation. The 32 patients in the control group underwent conventional therapy. During 12 months of folow-up, Majeed function score and inflammatory factor level changes and adverse events were observed and compared between the two groups.
RESULTS AND CONCLUSION:(1) Majeed function scores were significantly higher in both groups after treatment as compared with that preoperatively (alP< 0.05). The Majeed function scores were significantly higher in the observation group than in the control group 12 months after treatment (P< 0.05). (2) Inflammatory factor levels: Interleukin 6, C-reactive protein, and tumor necrosis factor alpha levels were significantly lower in both groups after treatment as compared with that preoperatively (alP< 0.05). No significant difference in above indexes was found between the two groups before and after treatment (P> 0.05). (3) Adverse events: one case affected incision infection after operation in the observation group. In the control group, four patients experienced incision infection. One suffered from nonunion, and one had bone necrosis. Above patients were treated in time, and were cured, so there wereno deaths. There were significant differences in the incidence of adverse events between the 2 groups (P< 0.05). (4) The research results show that cancelous bone screw fixation for unstable pelvic fractures can obtain satisfactory clinical results, andhave good biocompatibility.