1.Study on the Correlation between Tongue Features and Laboratory Indexes in Type 2 Diabetes Patients with Coronary Heart Disease
Naijin ZHANG ; Yin YUAN ; Huixia REN ; Mi ZHOU ; Ying LIU ; Shujiao YUE ; Yonghui LI ; Huaien BU ; Yuanyuan GUAN ; Hongwu WANG
World Science and Technology-Modernization of Traditional Chinese Medicine 2025;27(6):1734-1741
Objective To explore the correlation between tongue features of type 2 diabetes patients with coronary heart disease and glycosylated hemoglobin,liver function,blood lipids,C-reactive protein,so as to provide reference for related research.Methods Using the TFDA-1 tongue imaging device to collect patients'tongue images,experts will interpret the tongue images and extract objective parameters of the tongue images through the intelligent auxiliary diagnosis system of traditional Chinese medicine tongue diagnosis;Record patient laboratory indicators and use SPSS statistical software to analyze the correlation between tongue image distribution characteristics,tongue image parameter characteristics,and laboratory indicators using Spearman method.Results 702 patients with type 2 diabetes and coronary heart disease were included.In terms of glycated hemoglobin indicators,bruising parameters are positively correlated with HbA1c,while tongue tip RGB values are negatively correlated with HbA1c.In terms of liver function indicators,tongue edge redness,tongue tip and tongue texture R value are positively correlated with ALT and AST;Red tongue tip,tooth marks on the tongue,etc.are positively correlated with ALT;Fat tongue is positively correlated with AST.In terms of blood lipid indicators,parameters such as tooth mark tongue and tooth mark are positively correlated with TG;The parameters of white coating and tongue coating area are positively correlated with LDL-C;Thin coating is positively correlated with HDL-C,while thick coating is negatively correlated with HDL-C;Red tongue is negatively correlated with TCHO.In terms of C-reactive protein,red tongue,tip red,and edge red are positively correlated with CRP;The GB value of tongue root and tongue substance is negatively correlated with CRP.Conclusion Type 2 diabetes patients with coronary heart disease have tongue picture distribution,tongue shape parameters,tongue color parameters,coating color parameters and HbA1c,ALT,AST,TCHO,TG,HDL-C,LDL-C,CRP indicators in varying degrees of correlation.The combination of patients'tongue picture and laboratory indicators is helpful to clarify the diagnosis and prognosis of type 2 diabetes with coronary heart disease.
2.Study on the Correlation between Tongue Features and Laboratory Indexes in Type 2 Diabetes Patients with Coronary Heart Disease
Naijin ZHANG ; Yin YUAN ; Huixia REN ; Mi ZHOU ; Ying LIU ; Shujiao YUE ; Yonghui LI ; Huaien BU ; Yuanyuan GUAN ; Hongwu WANG
World Science and Technology-Modernization of Traditional Chinese Medicine 2025;27(6):1734-1741
Objective To explore the correlation between tongue features of type 2 diabetes patients with coronary heart disease and glycosylated hemoglobin,liver function,blood lipids,C-reactive protein,so as to provide reference for related research.Methods Using the TFDA-1 tongue imaging device to collect patients'tongue images,experts will interpret the tongue images and extract objective parameters of the tongue images through the intelligent auxiliary diagnosis system of traditional Chinese medicine tongue diagnosis;Record patient laboratory indicators and use SPSS statistical software to analyze the correlation between tongue image distribution characteristics,tongue image parameter characteristics,and laboratory indicators using Spearman method.Results 702 patients with type 2 diabetes and coronary heart disease were included.In terms of glycated hemoglobin indicators,bruising parameters are positively correlated with HbA1c,while tongue tip RGB values are negatively correlated with HbA1c.In terms of liver function indicators,tongue edge redness,tongue tip and tongue texture R value are positively correlated with ALT and AST;Red tongue tip,tooth marks on the tongue,etc.are positively correlated with ALT;Fat tongue is positively correlated with AST.In terms of blood lipid indicators,parameters such as tooth mark tongue and tooth mark are positively correlated with TG;The parameters of white coating and tongue coating area are positively correlated with LDL-C;Thin coating is positively correlated with HDL-C,while thick coating is negatively correlated with HDL-C;Red tongue is negatively correlated with TCHO.In terms of C-reactive protein,red tongue,tip red,and edge red are positively correlated with CRP;The GB value of tongue root and tongue substance is negatively correlated with CRP.Conclusion Type 2 diabetes patients with coronary heart disease have tongue picture distribution,tongue shape parameters,tongue color parameters,coating color parameters and HbA1c,ALT,AST,TCHO,TG,HDL-C,LDL-C,CRP indicators in varying degrees of correlation.The combination of patients'tongue picture and laboratory indicators is helpful to clarify the diagnosis and prognosis of type 2 diabetes with coronary heart disease.
3.Clinical observation on the effects of comprehensive hyperbaric oxygen therapy in the treatment of sudden deafness
Huaien ZHOU ; Jun CI ; Hua GUAN
Chinese journal of nautical medicine and hyperbaric medicine 2018;25(3):163-165
Objective To observe the clinical effects of comprehensive hyperbaric oxygen (HBO) therapy in the treatment of sudden deafness.Methods Ninety-eight patients (100 ears) hospitalized in the Department of Otorhinolaryngology,Hangzhou Red Cross Hospital from July 2015 to July 2017 were enrolled as research objects.All the patients were randomly divided into the HBO group and the control group,each consisting of 50 ears.Then,the groups were further divided into 3 subgroups:the low frequency descent group,the high frequency descent/fiat descent group and the full deafness group,by depending on the frequency and intensity of hearing loss.The control group was treated with nerve growth factor (NGF),Ginkgo biloba extract,Breviscapine needle and hormone,while the experiment group was supplemented with HBO in addition to the treatment received by the control group.After 3 courses of treatment,clinical effects and amplitude improvement in the impaired hearing frequency were compared between the 2 groups.Results Total effective rate of the experiment group was 94%,which was significantly higher than that of the control group (78%),with statistical significance(P < 0.05).Cure rate of the experimental group was 34%,which was higher than that of the control group (16%),also with statistical significance (P < 0.05).Total effective rate of the experimental group with flat descent and full deafness was 96%,which was also superior to that of the control group (73%),and statistical significance could be seen when comparisons were made between the groups (P <0.05).Conclusions HBO combined with NGF and other drugs could produce better efficacy,as compared with simple drug therapy.For this reason,it was worth further clinical extension.
4.Clinical observation on the effects of comprehensive hyperbaric oxygen therapy in the treatment of sudden deafness
Huaien ZHOU ; Jun CI ; Hua GUAN
Chinese journal of nautical medicine and hyperbaric medicine 2018;25(3):163-165
Objective To observe the clinical effects of comprehensive hyperbaric oxygen (HBO) therapy in the treatment of sudden deafness.Methods Ninety-eight patients (100 ears) hospitalized in the Department of Otorhinolaryngology,Hangzhou Red Cross Hospital from July 2015 to July 2017 were enrolled as research objects.All the patients were randomly divided into the HBO group and the control group,each consisting of 50 ears.Then,the groups were further divided into 3 subgroups:the low frequency descent group,the high frequency descent/fiat descent group and the full deafness group,by depending on the frequency and intensity of hearing loss.The control group was treated with nerve growth factor (NGF),Ginkgo biloba extract,Breviscapine needle and hormone,while the experiment group was supplemented with HBO in addition to the treatment received by the control group.After 3 courses of treatment,clinical effects and amplitude improvement in the impaired hearing frequency were compared between the 2 groups.Results Total effective rate of the experiment group was 94%,which was significantly higher than that of the control group (78%),with statistical significance(P < 0.05).Cure rate of the experimental group was 34%,which was higher than that of the control group (16%),also with statistical significance (P < 0.05).Total effective rate of the experimental group with flat descent and full deafness was 96%,which was also superior to that of the control group (73%),and statistical significance could be seen when comparisons were made between the groups (P <0.05).Conclusions HBO combined with NGF and other drugs could produce better efficacy,as compared with simple drug therapy.For this reason,it was worth further clinical extension.
5. Application of three-dimensional ultrasound for diagnosis of congenital preauricular fistula
Xialing ZHU ; Fei LIU ; Xiucai JIN ; Huaien ZHOU ; Yingyan ZHAO ; Haibo JIANG ; Baozhen ZHAO ; Wenfeng XIONG
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2017;52(10):771-773
Objective:
To explore the application of real-time three-dimensional ultrasound in locating the course, the brand and the blind end of internal opening of congenital preauricular fistula.
Methods:
Congenital preauricular fistula patients from Changhai Hospital were studied. All the cases were evaluated using two-dimensional and three-dimensional ultrasound before surgeries. The surgery findings were utilized as the gold standard. The imaging features of 3D ultrasound were described to determine the accuracy of the blind end location, the course of the main fistula tract and the branch tracts. The diagnosis was compared with the surgery findings.
Results:
In 89 cases, among which there were 21 branch fistulae. There were 68 bend fistulae without branch. The diagnostic accuracy of both two-dimensional ultrasound and three-dimensional ultrasound was 100%. The accuracy in locating the blind end of internal opening, the course of the branch tracts with 3D ultrasound was 92.1%(82/89), 85.7%(18/21) , compared to 80.9%(72/89), 57.1%(12/21) with 2D ultrasound. It was obvious that 3D ultrasound had more advantages. These differences were statistically significant (χ2=4.8,
6.Therapeutic effect of nasal endoscopesurgery on chronic sinusitis and nasalpolyps in geriatric patients
Hua GUAN ; Jun CI ; Ying FANG ; Changyang WANG ; Huaien ZHOU
Chinese Journal of Geriatrics 2015;34(4):421-423
Objective To investigate the therapeutic effect of nasal endoscope surgery on chronic sinusitis and nasal polyps in geriatric patients.Methods A total of 132 geriatric patients with chronic sinusitis and nasalpolyps underwent nasal endoscope surgery in our hospital from Jun.2010 to Jun.2014,and the therapeutic effect was investigated.Results In the 132 cases,92 cases were cured (69.7%).Therapeutic effects were excellent in 33 cases (25.0%),and invalid in 7 cases (5.3%).The total effective rate was 94.7%.The total effective rate was 100.0% in type Ⅰ,97.4% in type Ⅱ and 84.8% in type Ⅲ.The total effective rate was higher in type Ⅰ and Ⅱ than in type Ⅲ (x2=3.506 and 6.218,P=0.035 and 0.012).Local complications occurred in 10 cases (7.6%),including 1 case with nasolacrimal duct injury,2 cases with orbital hematoma,5 cases with nasal adhesion,1 case with surgical cavity hemorrhage and 1 case with sinus atresia.Conclusions The therapeutic effects of nasal endoscopesurgery on chronic sinusitis and nasalpolyps are good in geriatric patients,especially in treating chronic sinusitis and nasalpolyps of type Ⅰ and Ⅱ,and the postoperative complications are less,which is worth clinical application.

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