1.Clinicopathologic characteristics and prognostic analysis of follicular thyroid carci-nomas
Hongqun WANG ; Xin SONG ; Peng LIU ; Youjie GONG ; Ying LI ; Huaiyin SHI
Chinese Journal of Clinical and Experimental Pathology 2025;41(1):51-59
Purpose To investigate the clinicopathologic characteristics and prognostic factors of follicular thyroid carcinomas(FTC).Methods The clinical and pathological data of 205 FTC patients were collected,and the clinico-pathologic characteristics of FTC and its impact on prognosis were analyzed.Results The most common site of metas-tasis of FTC was bone(25.4%),which were mainly vertebrae and pelvis,followed by lung(15.6%).The factors that affecting distant metastasis(DM)were as follows:≥2 tumor foci,stage(Ⅲ-Ⅳ),patients'age(≥55 years,ex-tensive invasive type,recurrent FTC,postoperative/post-treatment recurrence and metastasis,and patients with com-plete tumor resection had less DM(P<0.05,respectively).The factors that affecting the number of tumor foci includ-ed age,stage(Ⅲ-Ⅳ),extensive invasive type,recurrent FTC,distant metastasis and history of hypertension,more recurrence and metastasis after surgery/treatment(P<0.05,respectively).Univariate survival analysis showed that factors affecting the overall survival(OS)and cancer-specific survival(CSS)of FTC were as follows:the number of tumor foci,stage,patients'age,surgical mode,extensive invasive type,DM,smoking,and postoperative/post-treat-ment recurrence.Cox multivariate regression analysis showed that stage,smoking and distant metastasis affected OS and/or CSS,and stage,extensive invasive type and recurrent FTC affected relapse-free survival(RFS).Compared with the group of FTC without undifferentiated carcinoma(UTC),the group of FTC with UTC had later stage(Ⅲ-Ⅳ,100.0%vs 32.0%),older age(≥ 60 years old,87.5%vs 37.6%),bigger size(>4 cm,100.0%vs 44.2%),higher proportion of extensive infiltration type(100.0%vs 33.3%),shorter survival time[CSS(4.429±1.152)months vs(120.415±5.765)months,P<0.001].Conclusion The most common site of distant metastasis of FTC is bone.Older patients,extensively invasive type and recurrent cancer are prone to multifocal and distant me-tastases.There were many prognostic factors affecting of FTC.The group of FTC with UTC has worse prognosis.
2.Clinicopathologic characteristics and prognostic analysis of follicular thyroid carci-nomas
Hongqun WANG ; Xin SONG ; Peng LIU ; Youjie GONG ; Ying LI ; Huaiyin SHI
Chinese Journal of Clinical and Experimental Pathology 2025;41(1):51-59
Purpose To investigate the clinicopathologic characteristics and prognostic factors of follicular thyroid carcinomas(FTC).Methods The clinical and pathological data of 205 FTC patients were collected,and the clinico-pathologic characteristics of FTC and its impact on prognosis were analyzed.Results The most common site of metas-tasis of FTC was bone(25.4%),which were mainly vertebrae and pelvis,followed by lung(15.6%).The factors that affecting distant metastasis(DM)were as follows:≥2 tumor foci,stage(Ⅲ-Ⅳ),patients'age(≥55 years,ex-tensive invasive type,recurrent FTC,postoperative/post-treatment recurrence and metastasis,and patients with com-plete tumor resection had less DM(P<0.05,respectively).The factors that affecting the number of tumor foci includ-ed age,stage(Ⅲ-Ⅳ),extensive invasive type,recurrent FTC,distant metastasis and history of hypertension,more recurrence and metastasis after surgery/treatment(P<0.05,respectively).Univariate survival analysis showed that factors affecting the overall survival(OS)and cancer-specific survival(CSS)of FTC were as follows:the number of tumor foci,stage,patients'age,surgical mode,extensive invasive type,DM,smoking,and postoperative/post-treat-ment recurrence.Cox multivariate regression analysis showed that stage,smoking and distant metastasis affected OS and/or CSS,and stage,extensive invasive type and recurrent FTC affected relapse-free survival(RFS).Compared with the group of FTC without undifferentiated carcinoma(UTC),the group of FTC with UTC had later stage(Ⅲ-Ⅳ,100.0%vs 32.0%),older age(≥ 60 years old,87.5%vs 37.6%),bigger size(>4 cm,100.0%vs 44.2%),higher proportion of extensive infiltration type(100.0%vs 33.3%),shorter survival time[CSS(4.429±1.152)months vs(120.415±5.765)months,P<0.001].Conclusion The most common site of distant metastasis of FTC is bone.Older patients,extensively invasive type and recurrent cancer are prone to multifocal and distant me-tastases.There were many prognostic factors affecting of FTC.The group of FTC with UTC has worse prognosis.
3. Analysis of annual hospitalization rate of pneumoconiosis patients and related influencing factors of social security
Lai WEI ; Huanqiang WANG ; Xiangpei LV ; Qianqian GAO ; Haiyan SONG ; Xin WANG ; Jie LIU ; Yuwen CHEN ; Hongqun ZHANG ; Xia HONG ; Lei HAN
Chinese Journal of Industrial Hygiene and Occupational Diseases 2019;37(9):656-659
Objective:
To study the main factors that influencing Pneumoconiosis patients' healthcare seeking behaviors.
Methods:
Conducting a descriptive analysis to analyze the relationship between the annual hospitalization rate and social security status (medical insurance, location of medical insurance, proportion of insurance used for reimbursement of pneumoconiosis, whether there is employment injury insurance at work, whether to apply for compensation after diagnosing pneumoconiosis, whether they receive social assistance and a minimum allowance) , social relationship status of patients (whether there is pneumoconiosis in the family or relatives, whether there is a pneumoconiosis in a friend or a colleague, and whether or not he/she has received financial assistance) , life quality of patients (subjective feelings) and living standard of patients (dietary level) based on data acquired from 120 pneumoconiosis patients.
Results:
The results of single factor analysis reveal that the location of medical insurance, the proportion of insurance for reimbursement of pneumoconiosis, whether there is employment injury insurance at work, whether to apply for compensation after diagnosing pneumoconiosis are statistically significant in pneumoconiosis patients' hospital utilization ratio (
4. Analysis of outpatient utilization of pneumoconiosis patients in Jiangsu province
Qianqian GAO ; Huanqiang WANG ; Xiangpei LV ; Lai WEI ; Haiyan SONG ; Xin WANG ; Jie LIU ; Yuwen CHEN ; Hongqun ZHANG ; Xia HONG ; Lei HAN
Chinese Journal of Industrial Hygiene and Occupational Diseases 2019;37(9):670-673
Objective:
To understand the situation and characteristics of out-patient utilization of urban and rural pneumoconiosis patients in Jiangsu province, and to provide a reference for the formulation of relevant policies.
Methods:
Using a questionnaire on patients with pneumoconiosis and their influencing factors, 120 patients with pneumoconiosis were randomly selected in Nanjing, Wuxi, Suzhou, Yancheng Vocational Defense Institute or CDC. The rate of outpatients with pneumoconiosis in urban and rural areas and the choice of out-patient hospitals were analyzed.
Results:
Of the 75 patients with severe pneumoconi-related symptoms such as chest tightness and dyspnea in the first two weeks of the survey, 36 (48.0%) lived in cities and 39 (52.0%) lived in rural areas. Patients with pneumoconiosis who live in urban and rural areas have different aggravating conditions within two weeks. Two weeks of aggravated symptoms in outpatient consultations accounted for36 (48.0%) . Of the 36 patients who used outpatient treatment, rural residents mainly chose 8 people from a hospital and a township health hospital, accounting for 34.8%, while 10 people from urban residents chose a nursing home or nursing home, accounting for 40.0%. The main reason why urban and rural pneumoconiosis patients did not go to the doctor is "conscious symptoms are lighter" and "feel that the doctor is useless."
Conclusion
The rate of outpatients with pneumoconiosis in Jiangsu province within two weeks is lower than that of ordinary elderly residents. There may be differences in treatment behavior patterns of urban and rural pneumoconiosis patients.Economic factors have a certain influence on the outpatient treatment behavior of pneumoconiosis patients. The recognition of outpatient service is the main factor affecting the outpatient treatment of pneumoconiosis patients. It is very important to popularize the knowledge of pneumoconiosis and do a good job in propaganda of occupational diseases and health education for pneumoconiosis patients. Focusing on the outpatient treatment of pneumoconiosis patients and making targeted medical policies is very important to standardize and improve the rehabilitation of pneumoconiosis patients.
5.Diagnostic value of two kinds of imaging of extracranial carotid artery stenosis in patients with transient ischemic attack
Xiuhai ZHANG ; Yanling WANG ; Zhaowei MENG ; Jianzeng ZHANG ; Hongqun SONG ; Aixiang GUO ; Xiangzhong LIU ; Yun ZHANG ; Yudong GUO
Chinese Journal of Postgraduates of Medicine 2011;34(22):26-29
Objective To evaluate the value of neck blood vessel colored doppler ultrasound (NBVCDU) and magnetic resonance angiography (MRA) to extracranial carotid artery stenosis in patients with transient ischemic attack (TIA).Methods After implementing NBVCDU and MRA examinations at the same time,45 TIA patients with at least one examination showing arteriostenosis in extracranial section were chosen to carry out cerebral digital subtraction angiography( DSA ),then the stenosis rate was calculated by American symptomatic carotid endarterectomy trial (NASCET) method.Results Regarding DSA as the gold standard,for 45 TIA patients that having 180 arteriostenosis in extracranial section, sensitivity,specificity,accuracy of NBVCDU examination was 93.51% ,95.15% ,94.44%, Kappa = 0.735; sensitivity,specificity,accuracy of MRA was 92.21% ,94.17% ,93.33% , Kappa =0.681; sensitivity,specificity,accuracy of NBVCDU combined with MPA was 97.40% ,99.03% ,98.33%, Kappa = 0.872.Conclusions The sensitivity and accuracy of arteriostenosis in extracranial section by NBVCDU examination is higher than that by MRA, and it is suitable in the crowd primary examination.NBVCDU combined with MRA has shown good consistence with DSA for diagnosing arteriostenosis in extracranial section,but can't replace DSA comlpetely.

Result Analysis
Print
Save
E-mail