1.Analysis of research topics on child and adolescent healthcare in community nursing based on LDA model
Chinese Journal of Modern Nursing 2025;31(16):2182-2188
Objective:To explore the current status and thematic content of child and adolescent healthcare in community nursing, so as to provide reference for research on child and adolescent healthcare in community nursing.Methods:Literature on child and adolescent healthcare in community nursing published from January 2004 to November 2024 in the Web of Science core collection database was systematically searched. Bibliometric methods were used to analyze the number of publications, journal distribution, and country distribution. The themes were analyzed using the latent Dirichlet allocation (LDA) model.Results:A total of 17 240 articles were included. The overall number of articles issued showed an upward trend year by year. Out of a total of 200 source publications, PLoS One ranked highest in terms of the number of articles issued (674) . A total of nine themes were obtained based on the LDA model, which further resulted in three merge topics, namely, the family environment of children and adolescents in community nursing and risk factors, the prevention and treatment of diseases and public health of children and adolescents in community nursing, and the social issues and mental health concerns of child and adolescent healthcare in community nursing. Conclusions:The research on child and adolescent healthcare in community nursing is generally on the rise, and the thematic analysis and mining of related studies provides a reference for child and adolescent healthcare services and related research in community nursing in China.
2.Cognition and influencing factors of rural child caregivers in the context of rural revitalization: a qualitative study
Yihui TIAN ; Fei ZHOU ; Huifeng WANG ; Hongmei DUAN
Chinese Journal of Modern Nursing 2025;31(24):3251-3257
Objective:To explore in depth the nurturing cognition of caregivers of children aged 1 to 7 years in rural areas in the context of rural revitalization, and to reveal the facilitating and hindering factors from the perspective of positive psychology, so as to provide scientific basis for improving the "family-centered" child nurturing care services in rural revitalization areas.Methods:This study utilized a descriptive qualitative research methodology. Semi-structured in-depth interviews were conducted in July 2024 with 20 visiting patients at the Outpatient Clinic of Shuangbai Maternal and Child Health Hospital in Chuxiong Yi Autonomous Prefecture of Yunnan Province. The data was organized and analyzed through the content analysis method.Results:Caregivers' nurturing cognition in the area were centered around three core themes, including perceptions and learning about nurturing, factors facilitating positive nurturing, and factors hindering positive nurturing.Conclusions:Caregivers in rural revitalization areas continue to face multidimensional challenges in their nurturing cognition and lack positive traits. The family factor is a significant barrier to the establishment of positive nurturing cognition. Healthcare professionals should make use of the perspective of positive psychology to analyze in-depth the cognition of caregivers and their influencing factors, and improve the "family-centered" child nurturing care services in rural revitalization areas.
3.Reliability and validity analysis of the attention deficit hyperactivity disorder self-report scale-revised among children aged 8-14
Pei ZHANG ; Lingrong XIAO ; Xian TIAN ; Gang ZHAO ; Hongmei WU
Chinese Journal of Behavioral Medicine and Brain Science 2025;34(1):71-77
Objective:To test the reliability and validity of the ADHD self-report scale-revised (ASRS-R) among Chinese children aged 8-14 and provide preliminary evidence for the use of ASRS-R as a tool for identifying attention deficit hyperactivity disorder (ADHD) symptoms in Chinese children aged 8-14 years.Methods:In October 2023, elementary school students aged 8-14 from five elementary school in Shenzhen were selected for the survey through convenience sampling. The subjects were tested using ASRS-R and strengths and difficulties questionnaire (SDQ). Among them, exploratory factor analysis and item analysis were conducted on sample 1 ( n=1 558), confirmatory factor analysis, calibration correlation validity and reliability analysis were conducted on sample 2 ( n=1 648), and retest reliability analysis was conducted on sample 3 ( n=300).The data was subjected to item analysis, exploratory factor analysis, confirmatory factor analysis, calibration correlation validity and reliability analysis by SPSS 25.0 and AMOS 23.0 softwares. Results:Exploratory factor analysis showed that the KMO value was 0.947, the cumulative variance contribution was 41.061%, and the loadings for the entries ranged from 0.454 to 0.697.The confirmatory factor analysis showed a good fit of the two-factor model ( χ2/ df=3.355, CFI=0.959, TLI=0.952, RMSEA=0.038, SRMR=0.029, AGFI=0.962, NFI=0.943, IFI=0.952), and was applicable to primary school students of different grades and genders. The internal consistency coefficients of the total scale, the dimensions of inattention and hyperactive/impulsivity were 0.876, 0.815, 0.769, respectively and the retest reliability of total scale was 0.984. Item analysis showed that the correlation coefficients between the score of each item and the total score of the scale ranged from 0.503 to 0.663(all P<0.01). Conclusion:The ASRS-R has good reliability and validity and is suitable for the identification of ADHD behavior in Chinese children aged 8-14.
4.Analysis of research topics on child and adolescent healthcare in community nursing based on LDA model
Chinese Journal of Modern Nursing 2025;31(16):2182-2188
Objective:To explore the current status and thematic content of child and adolescent healthcare in community nursing, so as to provide reference for research on child and adolescent healthcare in community nursing.Methods:Literature on child and adolescent healthcare in community nursing published from January 2004 to November 2024 in the Web of Science core collection database was systematically searched. Bibliometric methods were used to analyze the number of publications, journal distribution, and country distribution. The themes were analyzed using the latent Dirichlet allocation (LDA) model.Results:A total of 17 240 articles were included. The overall number of articles issued showed an upward trend year by year. Out of a total of 200 source publications, PLoS One ranked highest in terms of the number of articles issued (674) . A total of nine themes were obtained based on the LDA model, which further resulted in three merge topics, namely, the family environment of children and adolescents in community nursing and risk factors, the prevention and treatment of diseases and public health of children and adolescents in community nursing, and the social issues and mental health concerns of child and adolescent healthcare in community nursing. Conclusions:The research on child and adolescent healthcare in community nursing is generally on the rise, and the thematic analysis and mining of related studies provides a reference for child and adolescent healthcare services and related research in community nursing in China.
5.Cognition and influencing factors of rural child caregivers in the context of rural revitalization: a qualitative study
Yihui TIAN ; Fei ZHOU ; Huifeng WANG ; Hongmei DUAN
Chinese Journal of Modern Nursing 2025;31(24):3251-3257
Objective:To explore in depth the nurturing cognition of caregivers of children aged 1 to 7 years in rural areas in the context of rural revitalization, and to reveal the facilitating and hindering factors from the perspective of positive psychology, so as to provide scientific basis for improving the "family-centered" child nurturing care services in rural revitalization areas.Methods:This study utilized a descriptive qualitative research methodology. Semi-structured in-depth interviews were conducted in July 2024 with 20 visiting patients at the Outpatient Clinic of Shuangbai Maternal and Child Health Hospital in Chuxiong Yi Autonomous Prefecture of Yunnan Province. The data was organized and analyzed through the content analysis method.Results:Caregivers' nurturing cognition in the area were centered around three core themes, including perceptions and learning about nurturing, factors facilitating positive nurturing, and factors hindering positive nurturing.Conclusions:Caregivers in rural revitalization areas continue to face multidimensional challenges in their nurturing cognition and lack positive traits. The family factor is a significant barrier to the establishment of positive nurturing cognition. Healthcare professionals should make use of the perspective of positive psychology to analyze in-depth the cognition of caregivers and their influencing factors, and improve the "family-centered" child nurturing care services in rural revitalization areas.
6.Develop and validate an early risk prediction model for hip fracture among the elderly in community
Chunmei HE ; Hongying ZHANG ; Lijuan CHEN ; Linzhu XIONG ; Miao TIAN ; Tiancheng LIAO ; Hongmei JIANG ; Yan DOU
Modern Clinical Nursing 2025;24(3):15-23
Objective To investigate the incidence of hip fracture among the elderly in communities,explore related influencing factors,and develop and validate a risk prediction model.Methods A stratified sampling method was used to collect sociodemographic data,lifestyles and risk factors in hip fracture between January 2023 and January 2024 among the elderly residents in communities in Deyang.With random splitting,479 elderly people(68.00%)were assigned to the model training set,and 221(32.00%)to the model validation set.In the model training set,the participants were divided into a fracture group and a non-fracture group based on hip fracture or not.Data from both groups were compared,and R software(version 4.3.1)was employed to develop and validate the risk prediction model.Results A total of 700 elderly residents in communities were included,62 of them had hip fracture within one year yielding a cumulative incidence rate of 8.86%.The risk prediction model identified six predictors:frequent consumption of preserved foods,daily exercise time,daily sunlight exposure,osteoporosis,times of fall within a year,and with≥20 pieces of natural teeth.In the training set,the model achieved an AUC of 0.945(95%CI:0.908-0.982),with a sensitivity of 88.89%and a specificity of 89.40%.The calibration curve demonstrated a good agreement between predicted and actual values,indicating a strong calibration.Decision curve analysis(DCA)showed a positive net benefit.In the validation set,the AUC was 0.892(95%CI:0.784-0.999),with a sensitivity of 82.35%and a specificity of 93.63%,confirming a good model fit and predictive performance.The calibration curve exhibited a strong consistency,and DCA indicated a positive net benefit.Conclusion The developed risk prediction model for hip fracture in elderly community residents demonstrates a strong predictive value.It provides a practical reference for community workers and healthcare professionals to screen and assess the risk of hip fracture among the elderly residents in communities.
7.Emodin promotes autophagy to improve myocardial injury in septic model mice
Yong TIAN ; Qing ZHOU ; Chuanquan LUO ; Hongmei HU ; Changlin MA ; Lei YANG ; Lin WEI
Chinese Journal of Tissue Engineering Research 2025;29(26):5572-5578
BACKGROUND:Emodin has a variety of pharmacological activities such as anti-inflammatory,anti-viral and anti-oxidative stress,and also has a certain protective effect on sepsis-induced myocardial injury,but its mechanism of action is still unclear.OBJECTIVE:To investigate whether emodin can improve myocardial injury in septic mice by promoting autophagy.METHODS:Thirty-two male Kunming mice were divided into sham operation group(n=4),sham operation+emodin group(n=4),model group(n=8),model+emodin group(n=8),and emodin+3-methyladenine group(n=8).The myocardial injury model of septic mice was constructed by cecal ligation and puncture.3-methyladenine(10 mg/kg)was injected intraperitoneally 1 hour before modeling.Emodin(20 mg/kg)was injected intraperitoneally 30 minutes before modeling,and the other groups were injected with the same amount of normal saline at the same time point.Blood and myocardial samples were collected from all mice 24 hours after surgery.ELISA was used to detect the levels of brain natriuretic peptide and cardiac troponin Ⅰ in serum.Western blot assay was used to detect the protein expression of LC3B,Beclin-1,and p62 in myocardial tissue.Hematoxylin-eosin staining was used to observe the pathological changes in myocardial tissue.Ultrasound was used to evaluate the cardiac function of mice.RESULTS AND CONCLUSION:(1)Compared with the sham operation group,there was no significant difference in the levels of serum brain natriuretic peptide,cardiac troponin Ⅰ,and the protein expression of myocardial autophagy proteins LC3Ⅱ/LC3Ⅰ and p62 in the sham operation+emodin group(P>0.05).(2)Compared with the sham operation+emodin group,the levels of serum brain natriuretic peptide and cardiac troponin I were significantly increased in the model group(P<0.05).Compared with the model group,the levels of serum brain natriuretic peptide and cardiac troponin I were decreased in the model+emodin group(P<0.05).(3)Compared with the model group,the expression of LC3Ⅱ/LC3Ⅰ and Beclin-1 protein was increased and the expression of p62 protein was decreased in the myocardial tissue of the model+emodin group(P<0.05).Compared with the model+emodin group,the expression of LC3Ⅱ/LC3Ⅰ and Beclin-1 protein decreased and the expression of p62 protein increased in the emodin+3-methyladenine group(P<0.05).(4)The myocardial fibers in the sham operation group were normal,the myocardial fibers in the model group were disordered with a large number of inflammatory cell infiltration,the myocardial fibers in the model+emodin group were slightly disordered,and some vacuolar changes were observed.The myocardial fibers were disordered,and more inflammatory cell infiltration was observed in the emodin+3-methyladenine group.(5)Compared with the sham operation group,the left ventricular short axis shortening rate and left ventricular ejection fraction were decreased in the model group(P<0.05).Compared with the model group,the left ventricular short axis shortening rate and left ventricular ejection fraction were increased in the model+emodin group(P<0.05).Compared with the model+emodin group,the left ventricular ejection fraction of emodin+3-methyladenine group was decreased(P<0.05),and the left ventricular short axis shortening rate was reduced but not statistically significant(P>0.05).(6)The above results indicate that emodin pretreatment can improve myocardial injury and myocardial dysfunction in septic mice by promoting autophagy.
8.Develop and validate an early risk prediction model for hip fracture among the elderly in community
Chunmei HE ; Hongying ZHANG ; Lijuan CHEN ; Linzhu XIONG ; Miao TIAN ; Tiancheng LIAO ; Hongmei JIANG ; Yan DOU
Modern Clinical Nursing 2025;24(3):15-23
Objective To investigate the incidence of hip fracture among the elderly in communities,explore related influencing factors,and develop and validate a risk prediction model.Methods A stratified sampling method was used to collect sociodemographic data,lifestyles and risk factors in hip fracture between January 2023 and January 2024 among the elderly residents in communities in Deyang.With random splitting,479 elderly people(68.00%)were assigned to the model training set,and 221(32.00%)to the model validation set.In the model training set,the participants were divided into a fracture group and a non-fracture group based on hip fracture or not.Data from both groups were compared,and R software(version 4.3.1)was employed to develop and validate the risk prediction model.Results A total of 700 elderly residents in communities were included,62 of them had hip fracture within one year yielding a cumulative incidence rate of 8.86%.The risk prediction model identified six predictors:frequent consumption of preserved foods,daily exercise time,daily sunlight exposure,osteoporosis,times of fall within a year,and with≥20 pieces of natural teeth.In the training set,the model achieved an AUC of 0.945(95%CI:0.908-0.982),with a sensitivity of 88.89%and a specificity of 89.40%.The calibration curve demonstrated a good agreement between predicted and actual values,indicating a strong calibration.Decision curve analysis(DCA)showed a positive net benefit.In the validation set,the AUC was 0.892(95%CI:0.784-0.999),with a sensitivity of 82.35%and a specificity of 93.63%,confirming a good model fit and predictive performance.The calibration curve exhibited a strong consistency,and DCA indicated a positive net benefit.Conclusion The developed risk prediction model for hip fracture in elderly community residents demonstrates a strong predictive value.It provides a practical reference for community workers and healthcare professionals to screen and assess the risk of hip fracture among the elderly residents in communities.
9.Emodin promotes autophagy to improve myocardial injury in septic model mice
Yong TIAN ; Qing ZHOU ; Chuanquan LUO ; Hongmei HU ; Changlin MA ; Lei YANG ; Lin WEI
Chinese Journal of Tissue Engineering Research 2025;29(26):5572-5578
BACKGROUND:Emodin has a variety of pharmacological activities such as anti-inflammatory,anti-viral and anti-oxidative stress,and also has a certain protective effect on sepsis-induced myocardial injury,but its mechanism of action is still unclear.OBJECTIVE:To investigate whether emodin can improve myocardial injury in septic mice by promoting autophagy.METHODS:Thirty-two male Kunming mice were divided into sham operation group(n=4),sham operation+emodin group(n=4),model group(n=8),model+emodin group(n=8),and emodin+3-methyladenine group(n=8).The myocardial injury model of septic mice was constructed by cecal ligation and puncture.3-methyladenine(10 mg/kg)was injected intraperitoneally 1 hour before modeling.Emodin(20 mg/kg)was injected intraperitoneally 30 minutes before modeling,and the other groups were injected with the same amount of normal saline at the same time point.Blood and myocardial samples were collected from all mice 24 hours after surgery.ELISA was used to detect the levels of brain natriuretic peptide and cardiac troponin Ⅰ in serum.Western blot assay was used to detect the protein expression of LC3B,Beclin-1,and p62 in myocardial tissue.Hematoxylin-eosin staining was used to observe the pathological changes in myocardial tissue.Ultrasound was used to evaluate the cardiac function of mice.RESULTS AND CONCLUSION:(1)Compared with the sham operation group,there was no significant difference in the levels of serum brain natriuretic peptide,cardiac troponin Ⅰ,and the protein expression of myocardial autophagy proteins LC3Ⅱ/LC3Ⅰ and p62 in the sham operation+emodin group(P>0.05).(2)Compared with the sham operation+emodin group,the levels of serum brain natriuretic peptide and cardiac troponin I were significantly increased in the model group(P<0.05).Compared with the model group,the levels of serum brain natriuretic peptide and cardiac troponin I were decreased in the model+emodin group(P<0.05).(3)Compared with the model group,the expression of LC3Ⅱ/LC3Ⅰ and Beclin-1 protein was increased and the expression of p62 protein was decreased in the myocardial tissue of the model+emodin group(P<0.05).Compared with the model+emodin group,the expression of LC3Ⅱ/LC3Ⅰ and Beclin-1 protein decreased and the expression of p62 protein increased in the emodin+3-methyladenine group(P<0.05).(4)The myocardial fibers in the sham operation group were normal,the myocardial fibers in the model group were disordered with a large number of inflammatory cell infiltration,the myocardial fibers in the model+emodin group were slightly disordered,and some vacuolar changes were observed.The myocardial fibers were disordered,and more inflammatory cell infiltration was observed in the emodin+3-methyladenine group.(5)Compared with the sham operation group,the left ventricular short axis shortening rate and left ventricular ejection fraction were decreased in the model group(P<0.05).Compared with the model group,the left ventricular short axis shortening rate and left ventricular ejection fraction were increased in the model+emodin group(P<0.05).Compared with the model+emodin group,the left ventricular ejection fraction of emodin+3-methyladenine group was decreased(P<0.05),and the left ventricular short axis shortening rate was reduced but not statistically significant(P>0.05).(6)The above results indicate that emodin pretreatment can improve myocardial injury and myocardial dysfunction in septic mice by promoting autophagy.
10.Reliability and validity analysis of the attention deficit hyperactivity disorder self-report scale-revised among children aged 8-14
Pei ZHANG ; Lingrong XIAO ; Xian TIAN ; Gang ZHAO ; Hongmei WU
Chinese Journal of Behavioral Medicine and Brain Science 2025;34(1):71-77
Objective:To test the reliability and validity of the ADHD self-report scale-revised (ASRS-R) among Chinese children aged 8-14 and provide preliminary evidence for the use of ASRS-R as a tool for identifying attention deficit hyperactivity disorder (ADHD) symptoms in Chinese children aged 8-14 years.Methods:In October 2023, elementary school students aged 8-14 from five elementary school in Shenzhen were selected for the survey through convenience sampling. The subjects were tested using ASRS-R and strengths and difficulties questionnaire (SDQ). Among them, exploratory factor analysis and item analysis were conducted on sample 1 ( n=1 558), confirmatory factor analysis, calibration correlation validity and reliability analysis were conducted on sample 2 ( n=1 648), and retest reliability analysis was conducted on sample 3 ( n=300).The data was subjected to item analysis, exploratory factor analysis, confirmatory factor analysis, calibration correlation validity and reliability analysis by SPSS 25.0 and AMOS 23.0 softwares. Results:Exploratory factor analysis showed that the KMO value was 0.947, the cumulative variance contribution was 41.061%, and the loadings for the entries ranged from 0.454 to 0.697.The confirmatory factor analysis showed a good fit of the two-factor model ( χ2/ df=3.355, CFI=0.959, TLI=0.952, RMSEA=0.038, SRMR=0.029, AGFI=0.962, NFI=0.943, IFI=0.952), and was applicable to primary school students of different grades and genders. The internal consistency coefficients of the total scale, the dimensions of inattention and hyperactive/impulsivity were 0.876, 0.815, 0.769, respectively and the retest reliability of total scale was 0.984. Item analysis showed that the correlation coefficients between the score of each item and the total score of the scale ranged from 0.503 to 0.663(all P<0.01). Conclusion:The ASRS-R has good reliability and validity and is suitable for the identification of ADHD behavior in Chinese children aged 8-14.

Result Analysis
Print
Save
E-mail