1.Lessons from the 2024–2025 measles outbreak in southern Viet Nam
Thang Nguyen-Tien ; Hoa Minh Tran ; Anh Vu Le
Western Pacific Surveillance and Response 2026;17(2):64-67
Dong Nai province in southern Viet Nam was among the hardest hit in a measles outbreak in 2024–2025 with over 7000 cases. Our analysis outlines major takeaways for measles control in recommending the need for strengthened surveillance, digital communication and intersectoral collaboration to address immunization gaps and build health system resilience in Viet Nam.
2.Accessibility and utilization of sexual reproductive health services in a Vietnamese mountainous area: A mixed-method empirical study
Nguyen Thi Hoa Huyen ; Nguyen Chau Anh ; Hac Huyen My ; Tran Ngoc Tran ; Tran Le Minh Anh
Vietnam Journal of Public Health 2025;11(1):7-
Objectives: This study examined the accessibility and utilization of sexual and reproductive health (SRH) services among ethnic minority populations in Vietnam’s mountainous regions, with a focus on their perceptions and challenges.
Methods: A mixed-methods design was employed, combining a structured survey of 630 adults with semi-structured interviews and focus group discussions to capture both utilization patterns and contextual experiences.
Results: Most participants were of Thai ethnicity (77%). Commune health stations and district hospitals were the most frequently used facilities, primarily for genital tract diseases, pregnancy, and contraceptive services. Over 80% reported satisfaction with services; however, major barriers included long waiting times, limited transportation, and geographical isolation. Respondents expressed a preference for district-level and private facilities due to perceived higher quality, while residents in remote areas often relied on village midwives for maternal care. Additional challenges included the absence of school health staff and the financial burden on teachers providing basic medical support.
Conclusion: Findings highlight both service availability and persistent inequities. Addressing logistical, cultural, and systemic barriers through culturally sensitive policies and programs is essential to improving SRH equity for ethnic minority communities in Vietnam.
3.Active case finding to detect symptomatic and subclinical pulmonary tuberculosis disease: implementation of computer-aided detection for chest radiography in Viet Nam
Anh L Innes ; Andres Martinez ; Gia Linh Hoang ; Thi Bich Phuong Nguyen ; Viet Hien Vu ; Tuan Ho Thanh Luu ; Thi Thu Trang Le ; Victoria Lebrun ; Van Chinh Trieu ; Nghi Do Bao Tran ; Nhi Dinh ; Huy Minh Pham ; Van Luong Dinh ; Binh Hoa Nguyen ; Thi Thanh Huyen Truong ; Van Cu Nguyen ; Viet Nhung Nguyen ; Thu Hien Mai
Western Pacific Surveillance and Response 2024;15(4):14-25
Objective: In Viet Nam, tuberculosis (TB) prevalence surveys revealed that approximately 98% of individuals with pulmonary TB have TB-presumptive abnormalities on chest radiographs, while 32% have no TB symptoms. This prompted the adoption of the “Double X” strategy, which combines chest radiographs and computer-aided detection with GeneXpert testing to screen for and diagnose TB among vulnerable populations. The aim of this study was to describe demographic, clinical and radiographic characteristics of symptomatic and asymptomatic Double X participants and to assess multilabel radiographic abnormalities on chest radiographs, interpreted by computer-aided detection software, as a possible tool for detecting TB-presumptive abnormalities, particularly for subclinical TB.
Methods: Double X participants with TB-presumptive chest radiographs and/or TB symptoms and known risks were referred for confirmatory GeneXpert testing. The demographic and clinical characteristics of all Double X participants and the subset with confirmed TB were summarized. Univariate and multivariable logistic regression modelling was used to evaluate associations between participant characteristics and subclinical TB and between computer-aided detection multilabel radiographic abnormalities and TB.
Results: From 2020 to 2022, 96 631 participants received chest radiographs, with 67 881 (70.2%) reporting no TB symptoms. Among 1144 individuals with Xpert-confirmed TB, 51.0% were subclinical. Subclinical TB prevalence was higher in older age groups, non-smokers, those previously treated for TB and the northern region. Among 11 computer-aided detection multilabel radiographic abnormalities, fibrosis was associated with higher odds of subclinical TB.
Discussion: In Viet Nam, Double X community case finding detected pulmonary TB, including subclinical TB. Computer-aided detection software may have the potential to identify subclinical TB on chest radiographs by classifying multilabel radiographic abnormalities, but further research is needed.
4.STRESS IN RELATIONSHIP WITH BURNOUT DUE TO COVID-19: THE MODERATING ROLE OF COPING STRATEGIES
Tran Le Thanh ; Nguyen Thanh Hoang ; Nguyen Thi Mai Lan ; Vu Thu Trang ; Le Vu Ha ; Nguyen Thi Hoa Mai ; Cao Xuan Lieu ; Ha Thi Minh Chinh
ASEAN Journal of Psychiatry 2024;25(3):1-10
STRESS IN RELATIONSHIP WITH BURNOUT DUE TO COVID-19: THE MODERATING ROLE OF COPING STRATEGIES
This study investigates the relationship between stress and burnout related to the
COVID-19 pandemic, focusing on the moderating influence of positive and negative
coping strategies. In a cross-sectional survey involving 3,664 Vietnamese citizens aged 18
and above, the research explores the dynamics of stress and burnout symptoms associated
with the ongoing pandemic. The results reveal a negative impact of stress symptoms on
COVID-19-related burnout among the population. Notably, both positive and negative
coping strategies are identified as significant moderators in the interplay between stress
and burnout. This suggests that individuals’ coping mechanisms influence the severity
of stress and burnout experienced in dealing with COVID-19 challenges. These findings
contribute to the foundational understanding of the stress-burnout relationship during the
pandemic and provide essential insights for interventions. By recognizing the moderating
role of coping strategies, this study lays the groundwork for strategies aimed at enhancing
individuals’ coping abilities, ultimately reducing stress and burnout levels. These insights
hold the potential to assist individuals in adapting more effectively to the challenges posed
by the COVID-19 pandemic, fostering improved mental well-being in the face of ongoing
uncertainties. ASEAN Journal of Psychiatry, Vol. 25 (3) March, 2024; 1-10.
5.Explore patients’s expectations towards primary care and related factors at Family Medicine Clinic, Hue University of Medicine and Pharmacy
Thi Hoa NGUYEN ; Thi Cuc NGUYEN ; Thi Phuong Thuy HO ; Thi Xuan Thuy HO ; Thi Truc Ly TRAN ; Duc Toan VO ; Minh Tam NGUYEN
Hue Journal of Medicine and Pharmacy 2023;13(7):83-92
Background: One of the most important elements for improving the primary care quality is to meet the growing needs of patients and to increase patient satisfaction. In-depth studies on patients’ expectation is vital for healthcare facilities to achieve a more reliable and valid healthcare outcome. This study aims: to explore people’s expectations towards primary care services and related factors at Family Medicine Clinic, Hue University of Medicine and Pharmacy. Methods: A mixed method study on 308 patients visiting the Family Physician Clinic, Hue University of Medicine and Pharmacy. Results: The most important aspects were: “Doctor provides correct diagnoses and cure it.”, “Doctor provides careful examination”, “Doctor takes full history taking”, “Doctor clearly explains diagnosis and treatment plan”, “List of medication covered by health insurance is enough and qualified”, “Doctor/healthcare worker ensures patient confidentiality” and “Healthcare workers are friendly”. There were differences in the expectations of prioritizing primary care services in different target groups. Younger patients groups placed more expectations on facility factors than older patient groups; Patients in different occupational groups differed in their expectations of healthcare workers and the quality of medical care.Conclusion: Factors related to health care workers and quality of medical care were the most prioritizing expectations at the Family Medicine Clinic. It is necessarry to improve primary care services to meet the expectations of different target groups.
6.Mental health and coping methods of medical students during the fourth wave of the Covid-19 pandemic: a descriptive cross-sectional study
Nhu Minh Hang TRAN ; Quang Ngoc Linh NGUYEN ; Tran Tuan Anh LE ; Thi Nguyet BUI ; Thi Hoa DANG ; Viet Trinh TRUONG ; Vu Quoc Huy NGUYEN
Hue Journal of Medicine and Pharmacy 2023;13(7):140-146
Background: The Covid-19 pandemic that occurred at the end of 2019, especially the fourth wave in Vietnam, has affected the world not only in terms of economy, society, and physical health but also affected the mental health of population in general and of medical students in particular. The use of different coping methods may be protective or risk factors for mental health problems. Objectives: 1. To investigate the prevalence of anxiety, stress, and depression among medical students during the Covid -19 pandemic 2. To describe several coping behavior among medical students during the pandemic. Subjects and methods: A descriptive cross-sectional study conducted on 2350 students of medicine programme range from the first year to the sixth year in the school year 2021 - 2022 at Hue University of Medicine and Pharmacy. Using the DASS-21 scale to survey anxiety, depression and stress in research subjects and a self-designed questionnaire to describe the coping methods of medical students. Results: out of 2350 sample, the prevelance of depression, anxiety, and stress was 38%, 33.2%, and 17% respectively. 13.8% had both anxiety and stress, 15.4% had both stress and depression, and 12.8% had a combination of anxiety, depression and stress. Coping behavior was commonly selected including: eating and sleeping regularly as usual (68.1%); doing exercise at home at least 5 days/week and 30 minutes/day (23.9%); 36.5% of students performed their favorite activities under appropriate conditions most of the time or often. In addition, 59.7% of students had learn new things on the internet, 4.5% of students had practiced meditation and relaxation, 2.9% of students had chosen to write a diary and things they were grateful for; 32% had still maintain contacted with friends via video calls, text messages and 34.4% had chosen to participate in volunteer activities. Conclusion: This study highlights a high rate of anxiety, stress and depression among medical students during the fouthth wave of the Covid-19 pandemic. Personal lifestyle changes and social activities were amongst the most comon coping behavior reported.
7.Trends in prediabetes and diabetes prevalence and associated risk factors in Vietnamese adults
That Thanh TON ; Anh Thi Ngoc TRAN ; Ich Thanh DO ; Hoa NGUYEN ; Thi Thanh Binh NGUYEN ; Minh Tu NGUYEN ; Van Anh Bao HA ; Anh Quoc TRAN ; Huu Khoi HOANG ; Binh Thang TRAN
Epidemiology and Health 2020;42():e2020029-
OBJECTIVES:
The prevalence of diabetes mellitus is rapidly increasing in Vietnam, particularly among adults aged over 45 years. This study estimated trends in diabetes and prediabetes prevalence and determined risk factors in Vietnamese adults (over 45 years).
METHODS:
A cross-sectional study was conducted based on data from an annual diabetes screening program among people aged 45-69 years in an urban city in central Vietnam (Da Nang). Joinpoint regression analyses were performed to calculate the annual percentage change and ptrend-values. Multinomial logistic regression analysis was used to determine risk factors.
RESULTS:
In total, 3,765 men and 9,149 women were included in this analysis. The age-adjusted prevalence of diabetes and prediabetes in 2017 was 11.4% and 52.9%, respectively. The prevalence of diabetes was higher in men (15.1%) than in women (10.3%), but that of prediabetes was similar in both genders (53.4% vs. 52.8%). The prevalence of prediabetes significantly increased during the study period, whereas no upward or downward trend for diabetes was observed. The prevalence of obesity, abdominal obesity, hypertension, and dyslipidemia showed no obvious trend. Obesity, a high waist-to-hip ratio, hypertension, more severe abdominal obesity, and dyslipidemia were significantly associated with a higher risk of diabetes and prediabetes.
CONCLUSIONS
Diabetes and prediabetes were more prevalent among people aged over 45 years than in the general population. Da Nang has experienced a marked increase in the prevalence of prediabetes. These findings have significant implications regarding the need for nationwide public health interventions and management aiming at diabetes prevention and control.
8.Trends in prediabetes and diabetes prevalence and associated risk factors in Vietnamese adults
That Thanh TON ; Anh Thi Ngoc TRAN ; Ich Thanh DO ; Hoa NGUYEN ; Thi Thanh Binh NGUYEN ; Minh Tu NGUYEN ; Van Anh Bao HA ; Anh Quoc TRAN ; Huu Khoi HOANG ; Binh Thang TRAN
Epidemiology and Health 2020;42():e2020029-
OBJECTIVES:
The prevalence of diabetes mellitus is rapidly increasing in Vietnam, particularly among adults aged over 45 years. This study estimated trends in diabetes and prediabetes prevalence and determined risk factors in Vietnamese adults (over 45 years).
METHODS:
A cross-sectional study was conducted based on data from an annual diabetes screening program among people aged 45-69 years in an urban city in central Vietnam (Da Nang). Joinpoint regression analyses were performed to calculate the annual percentage change and ptrend-values. Multinomial logistic regression analysis was used to determine risk factors.
RESULTS:
In total, 3,765 men and 9,149 women were included in this analysis. The age-adjusted prevalence of diabetes and prediabetes in 2017 was 11.4% and 52.9%, respectively. The prevalence of diabetes was higher in men (15.1%) than in women (10.3%), but that of prediabetes was similar in both genders (53.4% vs. 52.8%). The prevalence of prediabetes significantly increased during the study period, whereas no upward or downward trend for diabetes was observed. The prevalence of obesity, abdominal obesity, hypertension, and dyslipidemia showed no obvious trend. Obesity, a high waist-to-hip ratio, hypertension, more severe abdominal obesity, and dyslipidemia were significantly associated with a higher risk of diabetes and prediabetes.
CONCLUSIONS
Diabetes and prediabetes were more prevalent among people aged over 45 years than in the general population. Da Nang has experienced a marked increase in the prevalence of prediabetes. These findings have significant implications regarding the need for nationwide public health interventions and management aiming at diabetes prevention and control.
9.Study PML/RAR alpha fusion gene on 21 patients diagnosed with acute promyelocytic leukemia (AML \u2013 M3)
Phuong Minh Vu ; Vinh Quang Pham ; Hoa Khanh Bach ; Nhung Thi Hong Le ; Dung Thi My Tran ; Phuong Minh Nguyen
Journal of Medical Research 2008;58(5):18-24
Background: In Vietnam, there are a number of studies on the application of ATRA in treating acute promyelocytic leukemia (AML \u2013 M3) but they have still faced with certain difficulties. Objectives: (1). Study PML/RAR alpha fusion gene on the patients diagnosed with AML \u2013 M3. (2). Study the index of hematology of the PML/RAR alpha positive group. Subject and Method: 21 patients with acute promyelocytic leukemia (M3) were studied. All patients were examined with morphology, coagulation and cytogenetic tests and RNA were extracted from leukemic cells and PCR for PML/RAR alpha fusion transcript. Result and conclusion: PML/RAR alpha positive in 67% including 4 patients which were not discovered t(15; 17) by cytogenetic technique. Rates of three subtype (bcr1, bcr2 and bcr3) of PML/RAR alpha were 7 patients (50%), 3 patients (21,5%) and 4 patients (28,5%), respectively. WBC and bone marrow cells of PML/RAR alpha positive group were 5.08+/-3.87 and 155.82+/-106.21. D \u2013 Dimer level was 1954.89+/-1575.28; 93% of patients in the PML/RAR alpha positive group had DIC.
Acute promyelocytic leukemia
;
M3
;
PML/RAR alpha
10.Research on AML1/ETO fusion gene on 76 patients diagnosed with acute myelogenous leukemia
Phuong Minh Vu ; Vinh Quang Pham ; Hoa Khanh Bach ; Nhung Thi Hong Le ; Dung Thi My Tran ; Phuong Minh Nguyen
Journal of Medical Research 2008;59(6):10-16
Background: Chromosome mutation type t(8;21) has quite a high frequency in acute myelogenous leukemia, which accounted for about 15% among adult patients. From 2001, the WHO has a new classification for acute myelogenous leukemia based on genetic mutations. Form had AML1/ETO were arranged into genetic mutation group with better prognosis and ability to fully recover after chemotherapy with a high dose of cytarabin. Objective: Study AML1/ETO fusion gene on the patients diagnosed with Acute Myelogenous Leukemia (AML), as well as the clinical features and some haematologic parameters of the AML1/ETO positive group. Subject and methods: 76 patients with AML were treating in the National Institute of Hematology & Blood Transfusion and the Department of Hematology & Blood Transfusion of Bach Mai Hospital from April 2007 to July 2008. These patients were studied for clinical examination, morphology and RNA were extracted from leukemic cells and PCR for AML1/ETO fusion transcript was performed. Results and conclusions: The incidence of AML1/ETO positive in the AML patients was 24%. The incidence of AML1/ETO positive in AML-M2 was 28%. In the AML1/ETO positive group: median age was 26.94+/-9.22; rate of severe anemia, hemorrhage, fever, infection, hepatomegaly, splenomegaly, lymphadenopathy and gum hypertrophy was 44%, 33%, 28%, 11%, 44%, 28%, 17% and 6%, respectively. Median hemoglobin, WBC, platelet, bone marrow cell count, % blast in peripheral blood and in bone marrow was 84.41+/-28.97 g/l, 29.42+/-31.36 g/l, 42.12+/-33.83 g/l, 215.93+/-134.42 g/l, 56.21+/-26.58% and 65.14+/-16.12%, respectively.
acute myelogenous leukemia
;
AML1/ETO fusion gene


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