1.Exploring on Quality Evaluation Methods of Clinical Case Reports in Traditional Chinese Medicine Based on China Clinical Cases Library of Traditional Chinese Medicine
Kaige ZHANG ; Feng ZHANG ; Bo ZHOU ; Haimin CHEN ; Yong ZHU ; Changcheng HOU ; Liangzhen YOU ; Weijun HUANG ; Jie YANG ; Guoshuang ZHU ; Shukun GONG ; Jianwen HE ; Yang YE ; Yuqiu AN ; Chunquan SUN ; Qingjie YUAN ; Buman LI ; Xingzhong FENG ; Kegang CAO ; Hongcai SHANG ; Jihua GUO ; Xiaoxiao ZHANG ; Zhining TIAN
Chinese Journal of Experimental Traditional Medical Formulae 2026;32(1):271-276
As the core vehicle for preserving and transmitting traditional Chinese medicine(TCM) academic thought and clinical experience, the establishment of a robust quality evaluation system for TCM clinical case reports is a crucial component in the current standardization and modernization of TCM. Based on the practical experience of constructing the China Clinical Cases Library of Traditional Chinese Medicine by the China Association of Chinese Medicine, this study conducted a comprehensive analysis of critical challenges, including insufficient authenticity and unfocused evaluation criteria. It proposed a three-dimensional evaluation framework grounded in the structure-process-outcome logic, encompassing three dimensions of authenticity and standardization, characteristics and advantages, application and translational impact. This framework integrated 12 key evaluation indicators in a systematic manner. The model preserved the academic characteristics of TCM syndrome differentiation and treatment, while aligning with modern scientific research standards, achieving a balance between individualized TCM experience and standardized evaluation. Concurrently, this study provided theoretical foundations and methodological guidance for evaluating the quality of TCM clinical cases, contributing significantly to the inheritance of TCM knowledge, evidence-based practice, and the reform of talent evaluation mechanisms.
2.Effect of Fengbei Huayu Capsule on FasL Gene Expression and T Cell Apoptosis of Type 2 Diabetic Rats
Haimin GONG ; Wenzhuo DUAN ; Guangxiang JIN
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(07):-
Objective To study the effect of Fengbei Huayu capsule on FasL gene expression and T cell apoptosis of type 2 diabetic rats, and to compare the pathological lesions of kidney and retina after treatment of traditional medicine. Methods To make the model of type 2 diabetic rats and determine the indexes of FasL gene expression and T cell apoptosis rate by RT-PCR, DNA gel electrophoresis methods. Results Compared the FasL gene expression and T cell apoptosis rate, TCM treatment group was significantly lower (P 0.05). Comparison of FasL gene express, TCM treatment group was significantly lower (P
3.Fingerprint of Rhizoma Polygoni Cuspidati
Haimin LEI ; Wei BI ; Qiang LI ; Weihong GONG ; Xian HUANG ; Yuxin ZHOU
Chinese Traditional and Herbal Drugs 1994;0(07):-
Objective To study a fingerprint of raw material of Rhizoma Polygoni Cuspidati from(various) habitats by RP-HPLC. Methods Kromasil C_(18) column(150 mm?4.6 mm,5 ?m) was used,with mixtures of acetonitrile and water as mobile phase in a gradient mode.The flow rate was 1 mL/min and wavelength was 303 nm.Results According to the optimum chromatographic conditions,a good fingerprint of Rhizoma Polygoni Cuspidati has been described.Conclusion The method is simple and accurate with good reproducibility.It may be practical value for the quality control of sample for Rhizoma Polygoni Cuspidati from various habitats.
4.Effect of hyperglycemia on the expressive type transformation of vascular smooth muscle cell in rats
Wenzhuo DUAN ; Jiafu WANG ; Yi DING ; Tongmei LIU ; Xiuyuan SONG ; Jianying WANG ; Haimin GONG ; Chaoshu TANG ; Xia LI
Chinese Journal of Pathophysiology 1986;0(01):-
AIM: To make hyperglycemia models and observe the effects of hyperglycemia on expressive type transformation of vascular smooth muscle cell (VSMC) in rats METHODS: Using tissue culture and radioactivity analysis methods RESULTS:①Hyperglycemia group was lower than control group in NO - 2 content, nitric oxide synthase activity and cGMP content;②Hyperglycemia group was higher than control group in endothelin, insulin, total chdesterol and [ 3H]-TdR penetrated rate of VSMC CONCLUSION: It was possible that hyperglycemia reduces the expressive type of VSMC to change and promotes VSMC proliferation

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