1.Retrospective Comparative Analysis of Clinical and Functional Outcome After Arthroscopic Bankart Repair using All-Suture Anchor and Metal Anchor
Jain V ; Gupta H ; Mehta N ; Joshi D ; Ajay ; Kataria H
Malaysian Orthopaedic Journal 2024;18(No.1):11-18
Introduction: Both knotted all suture anchors and metal
anchors are used for arthroscopic Bankart repair. We
retrospectively evaluated and compared clinical and
functional outcomes after arthroscopic Bankart repair using
the knotted all-suture anchors and knotted metal anchors.
Materials and methods: In a retrospective cohort analysis,
patients who underwent arthroscopic Bankart repair without
any concomitant additional lesion repair using either allsuture anchors or metal anchors, between January 2015 and
May 2018 were identified. Their pre- and post-operative
functional and clinical outcomes were compared using Rowe
and WOSI scores. The recurrence rate in the two groups was
also compared.
Results: A total of 41 patients in all suture anchors group and
47 in the metal anchors group were identified as per
inclusion and exclusion criteria. The demographic profile of
both groups was comparable. There was no significant
difference in clinical and functional outcome between the
two suture anchor groups as per Rowe (pre-operative
40.13+6.51 vs 38.09+6.24 and post-operative 2 years
93.28+7.09 vs 92.55+9.2) and WOSI (pre-operative
943.05+216.64 vs 977.55+165.46 and post-operative 2 years
278.21+227.56 vs 270.94+186.25) scores. There was a
significant improvement in both the groups between preoperative and post-operative ROWE and WOSI scores at 6
months and 2 years follow-up as compared to pre-operative
scores (p<0.001). Re-dislocation rates were also comparable
(4.8% vs 6.3%).
Conclusion: All-suture anchors showed comparable clinical
and functional results as the metal anchors for arthroscopic
Bankart repair at two-year follow-up.
2.Optimal Management of Asymptomatic Carotid Stenosis: Counterbalancing the Benefits with the Potential Risks
Kosmas I. PARASKEVAS ; Dimitri P. MIKHAILIDIS ; Hediyeh BARADARAN ; Alun H. DAVIES ; Hans-Henning ECKSTEIN ; Gianluca FAGGIOLI ; Jose Fernandes e FERNANDES ; Ajay GUPTA ; Mateja K. JEZOVNIK ; Stavros K. KAKKOS ; Niki KATSIKI ; M. Eline KOOI ; Gaetano LANZA ; Christos D. LIAPIS ; Ian M. LOFTUS ; Antoine MILLON ; Andrew N. NICOLAIDES ; Pavel POREDOS ; Rodolfo PINI ; Jean-Baptiste RICCO ; Tatjana RUNDEK ; Luca SABA ; Francesco SPINELLI ; Francesco STILO ; Sherif SULTAN ; Clark J. ZEEBREGTS ; Seemant CHATURVEDI
Journal of Stroke 2022;24(1):163-165
3.Management of Patients with Asymptomatic Carotid Stenosis May Need to Be Individualized: A Multidisciplinary Call for Action
Kosmas I. PARASKEVAS ; Dimitri P. MIKHAILIDIS ; Hediyeh BARADARAN ; Alun H. DAVIES ; Hans-Henning ECKSTEIN ; Gianluca FAGGIOLI ; Jose Fernandes e FERNANDES ; Ajay GUPTA ; Mateja K. JEZOVNIK ; Stavros K. KAKKOS ; Niki KATSIKI ; M. Eline KOOI ; Gaetano LANZA ; Christos D. LIAPIS ; Ian M. LOFTUS ; Antoine MILLON ; Andrew N. NICOLAIDES ; Pavel POREDOS ; Rodolfo PINI ; Jean-Baptiste RICCO ; Tatjana RUNDEK ; Luca SABA ; Francesco SPINELLI ; Francesco STILO ; Sherif SULTAN ; Clark J. ZEEBREGTS ; Seemant CHATURVEDI
Journal of Stroke 2021;23(2):202-212
The optimal management of patients with asymptomatic carotid stenosis (ACS) is the subject of extensive debate. According to the 2017 European Society for Vascular Surgery guidelines, carotid endarterectomy should (Class IIa; Level of Evidence: B) or carotid artery stenting may be considered (Class IIb; Level of Evidence: B) in the presence of one or more clinical/imaging characteristics that may be associated with an increased risk of late ipsilateral stroke (e.g., silent embolic infarcts on brain computed tomography/magnetic resonance imaging, progression in the severity of ACS, a history of contralateral transient ischemic attack/stroke, microemboli detection on transcranial Doppler, etc.), provided documented perioperative stroke/death rates are <3% and the patient’s life expectancy is >5 years. Besides these clinical/imaging characteristics, there are additional individual, ethnic/racial or social factors that should probably be evaluated in the decision process regarding the optimal management of these patients, such as individual patient needs/patient choice, patient compliance with best medical treatment, patient sex, culture, race/ethnicity, age and comorbidities, as well as improvements in imaging/operative techniques/outcomes. The present multispecialty position paper will present the rationale why the management of patients with ACS may need to be individualized.
4.C-reactive protein (CRP) and Erythrocyte Sedimentation Rate (ESR) Trends following Total Hip and Knee Arthroplasties in an Indian Population – A Prospective Study
Krishna A ; Garg S ; Gupta S ; Bansal H
Malaysian Orthopaedic Journal 2021;15(No.2):143-150
Introduction: To evaluate the trends of C-reactive protein
(CRP) and Erythrocyte sedimentation rate (ESR) in the first
three weeks after uncomplicated total hip (THR) and total
knee (TKR) arthroplasty/replacement in the Indian
population and to compare it with available literature.
Material and methods: A total of 90 patients were enrolled
for this prospective study, of which 30 were unilateral THR,
30 were unilateral TKR (U/L TKR) and 30 were
simultaneous bilateral TKR (B/L TKR). Serum CRP and
ESR were measured on the day before surgery and postoperatively on day 1st, 2nd, 3rd, 7th, 12th, and at the end of
3rd week.
Results: CRP showed a peak at day 2nd with normalisation
to pre-operative value by the end of 3rd week. While ESR
showed a peak on day 3rd and continued to remain elevated
even at end of 3rd week post-operatively. Both mean CRP
and ESR values were higher in THR patients followed by in
B/L TKR and then in U/L TKR patients.
Conclusion: CRP persists to be the best acute phase reactant
in the early post-operative phase with a relatively typical
pattern as compared to ESR. CRP values peak at postoperative day 2nd and then show a gradual decline.
However, its normalisation to pre-operative baseline values
may vary among different groups of population.
5.Management of Patients with Asymptomatic Carotid Stenosis May Need to Be Individualized: A Multidisciplinary Call for Action
Kosmas I. PARASKEVAS ; Dimitri P. MIKHAILIDIS ; Hediyeh BARADARAN ; Alun H. DAVIES ; Hans-Henning ECKSTEIN ; Gianluca FAGGIOLI ; Jose Fernandes e FERNANDES ; Ajay GUPTA ; Mateja K. JEZOVNIK ; Stavros K. KAKKOS ; Niki KATSIKI ; M. Eline KOOI ; Gaetano LANZA ; Christos D. LIAPIS ; Ian M. LOFTUS ; Antoine MILLON ; Andrew N. NICOLAIDES ; Pavel POREDOS ; Rodolfo PINI ; Jean-Baptiste RICCO ; Tatjana RUNDEK ; Luca SABA ; Francesco SPINELLI ; Francesco STILO ; Sherif SULTAN ; Clark J. ZEEBREGTS ; Seemant CHATURVEDI
Journal of Stroke 2021;23(2):202-212
The optimal management of patients with asymptomatic carotid stenosis (ACS) is the subject of extensive debate. According to the 2017 European Society for Vascular Surgery guidelines, carotid endarterectomy should (Class IIa; Level of Evidence: B) or carotid artery stenting may be considered (Class IIb; Level of Evidence: B) in the presence of one or more clinical/imaging characteristics that may be associated with an increased risk of late ipsilateral stroke (e.g., silent embolic infarcts on brain computed tomography/magnetic resonance imaging, progression in the severity of ACS, a history of contralateral transient ischemic attack/stroke, microemboli detection on transcranial Doppler, etc.), provided documented perioperative stroke/death rates are <3% and the patient’s life expectancy is >5 years. Besides these clinical/imaging characteristics, there are additional individual, ethnic/racial or social factors that should probably be evaluated in the decision process regarding the optimal management of these patients, such as individual patient needs/patient choice, patient compliance with best medical treatment, patient sex, culture, race/ethnicity, age and comorbidities, as well as improvements in imaging/operative techniques/outcomes. The present multispecialty position paper will present the rationale why the management of patients with ACS may need to be individualized.
6.A Comparison of the Reliability of the Patellar Tendon-Trochlear Groove (PTTG) Distance and the Tibial Tuberosity-Trochlear Groove (TTTG) Distance Measured on MRI
Gupta H, MS Ortho ; Batta NS, DNB Radiodiag ; Kataria H, MS Ortho ; Batra V, MD Radiodiag ; Upadhyay AD, PhD ; Jain V, MS Ortho ; Mishra P, MS Ortho ; Goel N, MS Ortho
Malaysian Orthopaedic Journal 2020;14(No.1):34-41
Introduction: An increased tibial tuberosity-trochlear groove (TTTG) distance is used for deciding a treatment plan in patello-femoral instability (PFI). The centre of the patellar tendon and the chondral trochlear groove can be directly visualised on MRI, and measured, giving the patellar tendontrochlear groove (PTTG) distance. A study was designed to compare the inter-rater and the test-retest reliabilities of PTTG and TTTG measurements in MRI of patients without PFI and in a group with PFI. Materials and Methods:This cross-sectional reliability study was done on archival MRI films of 50 patients without patellar instability and 20 patients with patellar instability. TTTG and PTTG distances were independently measured by two orthopaedic surgeons and two radiologists. A hybrid PTTG measurement with bony landmarks on the femoral side and the patellar tendon landmark on the tibial side, was used to estimate the influence of the differences in the femoral and tibial landmarks on the difference in reliabilities. The intra-class correlation coefficient (ICC) was calculated for all four raters, as well as separately for each rater. Results: The PTTG distance had a higher inter-rater reliability (ICC=0.86, 95% CI=0.79-0.92) compared to the TTTG distance (ICC=0.70, 95% CI=0.59-0.80) in patients without PFI. Similar trends were seen in patients with PFI (0.83 vs 0.66). The inter-rater reliability for the hybrid PTTG distance was found to lie in between the TTTG and PTTG. Conclusions:The MRI-based PTTG distance had better inter-rater reliability compared with the MRI-based TTTG distance.
7.Recent Advances in the Development of Experimental Therapeutics for Levodopa-Induced Dyskinesia
Michael L MARTINI ; Sean N NEIFERT ; J MOCCO ; Fedor PANOV ; Winona TSE ; Ruth H WALKER ; Jian JIN ; Fiona GUPTA
Journal of Movement Disorders 2019;12(3):161-165
No abstract available.
Dyskinesias
8.Drug-induced immune haemolytic anaemia caused by levofloxacin.
Shashvat SUKHAL ; Shweta GUPTA
Singapore medical journal 2014;55(8):e136-8
Drug-induced immune haemolytic anaemia (DIIHA) is extremely rare. We herein report a case of life-threatening DIIHA due to levofloxacin. This is the second case reported in the literature. A 51-year-old woman presented with complaints of fatigue after 4-5 days of levofloxacin therapy for a lung infection. At presentation, she was found to have haemolysis with a positive Coombs test and IgG autoantibodies. Levofloxacin was identified as the probable culprit, using the Naranjo adverse drug reaction probability scale. Upon discontinuation of the drug and initiation of steroids, the patient's haematological parameters stabilised. Diagnosis of DIIHA is made through a history of intake of levofloxacin, clinical and laboratory features of haemolysis and a positive Coombs test. An autoantibody screen is most commonly positive for warm antibodies (IgG type). It is essential for clinicians to recognise this rare complication caused by a commonly prescribed medication, discontinue the offending drug and initiate treatment.
Anemia, Hemolytic
;
chemically induced
;
Anti-Bacterial Agents
;
adverse effects
;
therapeutic use
;
Autoantibodies
;
blood
;
Female
;
Fluoroquinolones
;
adverse effects
;
Hemolysis
;
Humans
;
Immunoglobulin G
;
blood
;
Levofloxacin
;
adverse effects
;
Male
;
Middle Aged
;
Steroids
;
therapeutic use
9.Gastric Cancer Presenting as a Krukenberg Tumor at 22 Weeks' Gestation.
Paul Vincent CO ; Ashutosh GUPTA ; Bashar M ATTAR ; Melchor DEMETRIA
Journal of Gastric Cancer 2014;14(4):275-278
Gastric cancer is rare during pregnancy, and often advanced upon presentation. A Krukenberg tumor presents a diagnostic and therapeutic challenge in the pregnant patient. We present a case of a 38-year-old woman at 22 weeks' gestation who presented with worsening epigastric pain, and was found to have a left pelvic mass on ultrasound, which was confirmed by magnetic resonance imaging. She went into active labor and delivered a viable infant via vaginal delivery. An exploratory laparotomy revealed a large mass originating from her left ovary and diffuse thickening of the lesser curvature of the stomach. Frozen section investigation revealed the presence of signet cell adenocarcinoma. Subsequent upper endoscopy showed linitis plastica, while biopsy confirmed the presence of adenocarcinoma. In conclusion, the occurrence of gastric cancer in pregnancy is rare despite extremely common symptoms. The management poses a challenge because of the need for early treatment, and the continuation of the pregnancy.
Adenocarcinoma
;
Adult
;
Biopsy
;
Endoscopy
;
Female
;
Frozen Sections
;
Humans
;
Infant
;
Krukenberg Tumor*
;
Laparotomy
;
Linitis Plastica
;
Magnetic Resonance Imaging
;
Ovary
;
Pregnancy*
;
Stomach
;
Stomach Neoplasms*
;
Ultrasonography
10.Are Indians and females less tolerant to pain? An observational study using a laboratory pain model.
E Das Gupta ; A H Zailinawati ; A W Lim ; J B Chan ; S H Yap ; Y Y Hla ; M A Kamil ; C L Teng
The Medical journal of Malaysia 2009;64(2):111-3
In Malaysia, it is a common belief among health care workers that females and Indians have lower pain threshold. This experience, although based on anecdotal experience in the healthcare setting, does not allow differentiation between pain tolerance, and pain expression. To determine whether there is a difference in the tolerance to pain between the three main ethnic groups, namely the Malays, Chinese and Indians as well as between males and females. This was a prospective study, using a laboratory pain model (ischaemic pain tolerance) to determine the pain tolerance of 152 IMU medical students. The mean age of the students was 21.8 years (range 18-29 years). All of them were unmarried. The median of ischaemic pain tolerance for Malays, Chinese and Indians were 639s, 695s and 613s respectively (p = 0.779). However, statistically significant difference in ischaemic pain tolerance for males and females Indian students were observed. Possible ethnic difference in pain tolerance in casual observation is not verified by this laboratory pain model. Difference in pain tolerance between genders is shown only for Indians.
Pain Threshold
;
Pain
;
Indian race
;
seconds
;
Models


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