1.Research progress of artificial intelligence in predicting the composition of kidney stones
Yongdong PAN ; Yunteng HUANG ; Guofeng XU
Chinese Journal of Urology 2025;46(2):157-160
Kidney stone disease (KSD) is a common urinary system disorder characterized by a complex composition of stones. Identifying the composition of kidney stones is of great significance for their treatment and prevention. With the application of artificial intelligence techniques such as machine learning and deep learning, efficient and accurate identification of the composition of kidney stones has been achieved, greatly improving the efficiency, accuracy, and preeminence of stone identification. It also provides new ideas and methods for the treatment of kidney stones. This article reviewed the literatures from three aspects: the clinical data of stone patients, medical images of stones, and direct visual images, combined with artificial intelligence. It has been found that most studies have achieved accurate predictions of the main components of stones, such as calcium stones or uric acid stones. However, due to limitations in the dataset and the complexity of stone compositions, there is still great potential in the identification and prediction of the composition of kidney stones using artificial intelligence.
2.Research progress of artificial intelligence in predicting the composition of kidney stones
Yongdong PAN ; Yunteng HUANG ; Guofeng XU
Chinese Journal of Urology 2025;46(2):157-160
Kidney stone disease (KSD) is a common urinary system disorder characterized by a complex composition of stones. Identifying the composition of kidney stones is of great significance for their treatment and prevention. With the application of artificial intelligence techniques such as machine learning and deep learning, efficient and accurate identification of the composition of kidney stones has been achieved, greatly improving the efficiency, accuracy, and preeminence of stone identification. It also provides new ideas and methods for the treatment of kidney stones. This article reviewed the literatures from three aspects: the clinical data of stone patients, medical images of stones, and direct visual images, combined with artificial intelligence. It has been found that most studies have achieved accurate predictions of the main components of stones, such as calcium stones or uric acid stones. However, due to limitations in the dataset and the complexity of stone compositions, there is still great potential in the identification and prediction of the composition of kidney stones using artificial intelligence.
3.Comparison of GMSV position and prone position in percutaneous nephroscopic surgery:a Meta-analysis
Shengnan LIU ; Yongdong PAN ; Guofeng XU
Journal of Modern Urology 2023;28(12):1069-1074
【Objective】 To evaluate the efficacy and safety of percutaneous nephrolithotomy in Galdakao-modified supine Valdivia (GMSV) position and prone position in the treatment of renal calculi. 【Methods】 PubMed, Embase and Cochrane Library databases were searched systematically to identify all eligible studies. Literature collected were screened and data were extracted by three authors independently. RevMan5.4 software was used for Meta-analysis. 【Results】 A total of 9 articles were enrolled, including 7 randomized controlled studies and 2 case-control studies, with a total of 1 690 patients. The results of Meta-analysis showed that compared with the prone position group, the GMSV group had shorter hospital stay (WMD:-9.04, 95%CI:-16.85--1.22, P=0.02), shorter intraoperative radiation exposure (WMD:-1.23, 95%CI:-1.98--0.48, P=0.001), lower rate of complications (RR:0.72, 95%CI:0.59-0.88, P=0.001), but there were no significant differences in operation time, primary stone clearance rate, postoperative hemoglobin loss, blood transfusion rate, fever rate and non-tubulization rate. 【Conclusion】 Compared with percutaneous nephrolithotomy in prone position, percutaneous nephrolithotomy in GMSV position has the comparable stone clearance rate, but has significant advantages in hospital stay, intraoperative radiation time, and overall complications. It is safe for the treatment of renal stones and upper ureteral stones.
4. Association between dust exposure and the risk of hypertension of male coal miners in Henan Province
Chenxi ZHI ; Xueyang LIU ; Hongwei PAN ; Guofeng LI ; Zhiheng LI ; Yingzheng ZHAO ; Haibin LI ; Xianyong GUO ; Sanqiao YAO
Chinese Journal of Preventive Medicine 2019;53(6):597-602
Objective:
To explore the association between dust exposure and the incidence of hypertension in male coal miners.
Methods:
Using the method of retrospective cohort study,a hypertension cohort of colliery in Henan Province was established in January 2006. From 2006 to 2017,all the male coal miners in a colliery who were exposed to dust were selected into the exposure group including tunneling, mining,auxiliary and combining workers, and workers from administrative logistics departments who were not exposed to dust were selected into the control group. The eligible participants should satisfy following conditions: working more than one year, with clear and complete record of occupation change, and with complete archives and reliable diagnosis of occupational health surveillance. The exclusion criteria of participants were with hypertension at the baseline of study or with heart,liver,kidney diseases and malignant tumors. A total of 12 647 participants were enrolled in this study (11 663 in the exposure group and 984 in the control group). The follow-up period was from January 2006 to December 2017,with a total follow-up of 89 259.75 person-years. Questionnaires and physical measurements were used to collect general demographic characteristics, occupational exposure history and occupational health surveillance data of all participants. The Cox proportional hazards regression model was used to estimate the association between the dust exposure and the incidence of hypertension.
Results:
During the follow-up period, 2 549 new-onset hypertension patients were identified with an incidence density of hypertension about 2 855.71 per 100 000 person-years. The incidence density of hypertension was 2 967.58 per 100 000 person-years in the exposure group, and 1 643.85 per 100 000 person-years in the control group. The results of multivariate Cox proportional hazards regression model showed that after the adjustment of marriage, age, smoking, alcohol drinking and body mass index,the risk of hypertension was higher in the exposure group compared with the control group (
5. Analysis of the prevalence of lower respiratory tract disease among coal dust-exposed workers
Xueyang LIU ; Chenxi ZHI ; Hongwei PAN ; Guofeng LI ; Zhiheng LI ; Yingzheng ZHAO ; Haibin LI ; Xianyong GUO ; Sanqiao YAO
Chinese Journal of Industrial Hygiene and Occupational Diseases 2019;37(7):509-513
Objective:
To investigate the prevalence and influencing factors of lower respiratory tract disease.
Methods:
The health physical examination data of 4000 coal dust exposed workers who had physical examination in the Institute of Occupational Disease Prevention and Treatment in 2016 were collected and analyzed with SPSS 20.0 software.
Results:
Out of the 4000 coal workers, the Prevalence rate of pulmonary tuberculosis, chronic bronchitis, CWP were 1.00% (40/4000) , 0.63% (25/4000) , 0.43% (17/4000) . 17 coal workers suffered from coal workers. The prevalence of workers both exposed to silicon and coal dust was 1.15% (2/174) , which was higher than that of other the job type. The prevalence of CWP among age groups, length of service and occupational category were found significant difference (
6.Recent advance in clinical application of deep brain stimulation
Chinese Journal of Neuromedicine 2019;18(9):957-961
Deep brain stimulation is widely used for treatment of neuropsychiatric diseases, showing its unique advantages in the treatment of central nervous diseases, such as epilepsy, Parkinson's disease, essential tremor, drug-refractory psychiatric diseases, drug-refractory pain, improvement of arousal and cognitive functions, and addiction diseases. After more than 30 years of clinical research, animal experiments and material research, the scopes and modes of DBS use have been fully developed, and important progress has been made in seeking better stimulation targets and modes. The complexity and individuality of the disease lead to differences in the response of each patient to DBS treatment, so it is necessary to further clarify its mechanism of action and explore better therapeutic targets and parameters to meet higher clinical requirements. This paper reviews the clinical application of DBS as follows.
7.Association between dust exposure and the risk of hypertension of male coal miners in Henan Province
Chenxi ZHI ; Xueyang LIU ; Hongwei PAN ; Guofeng LI ; Zhiheng LI ; Yingzheng ZHAO ; Haibin LI ; Xianyong GUO ; Sanqiao YAO
Chinese Journal of Preventive Medicine 2019;53(6):597-602
Objective To explore the association between dust exposure and the incidence of hypertension in male coal miners. Methods Using the method of retrospective cohort study,a hypertension cohort of colliery in Henan Province was established in January 2006. From 2006 to 2017,all the male coal miners in a colliery who were exposed to dust were selected into the exposure group including tunneling, mining,auxiliary and combining workers,and workers from administrative logistics departments who were not exposed to dust were selected into the control group. The eligible participants should satisfy following conditions: working more than one year, with clear and complete record of occupation change, and with complete archives and reliable diagnosis of occupational health surveillance. The exclusion criteria of participants were with hypertension at the baseline of study or with heart,liver,kidney diseases and malignant tumors. A total of 12 647 participants were enrolled in this study (11 663 in the exposure group and 984 in the control group). The follow?up period was from January 2006 to December 2017,with a total follow?up of 89 259.75 person?years. Questionnaires and physical measurements were used to collect general demographic characteristics, occupational exposure history and occupational health surveillance data of all participants. The Cox proportional hazards regression model was used to estimate the association between the dust exposure and the incidence of hypertension. Results During the follow?up period, 2 549 new?onset hypertension patients were identified with an incidence density of hypertension about 2 855.71 per 100 000 person?years. The incidence density of hypertension was 2 967.58 per 100 000 person?years in the exposure group, and 1 643.85 per 100 000 person?years in the control group. The results of multivariate Cox proportional hazards regression model showed that after the adjustment of marriage, age, smoking, alcohol drinking and body mass index,the risk of hypertension was higher in the exposure group compared with the control group ( HR=1.692, 95%CI : 1.410-2.032). Further analysis showed that compared with workers from administrative logistics departments,the risk of hypertension in tunneling,mining and auxiliary working was 1.629(1.345-1.973),1.677(1.374-2.046) and 1.782(1.475-2.151),respectively. Conclusion Dust exposure may increase the risk of hypertension in male coal miners.
8.Association between dust exposure and the risk of hypertension of male coal miners in Henan Province
Chenxi ZHI ; Xueyang LIU ; Hongwei PAN ; Guofeng LI ; Zhiheng LI ; Yingzheng ZHAO ; Haibin LI ; Xianyong GUO ; Sanqiao YAO
Chinese Journal of Preventive Medicine 2019;53(6):597-602
Objective To explore the association between dust exposure and the incidence of hypertension in male coal miners. Methods Using the method of retrospective cohort study,a hypertension cohort of colliery in Henan Province was established in January 2006. From 2006 to 2017,all the male coal miners in a colliery who were exposed to dust were selected into the exposure group including tunneling, mining,auxiliary and combining workers,and workers from administrative logistics departments who were not exposed to dust were selected into the control group. The eligible participants should satisfy following conditions: working more than one year, with clear and complete record of occupation change, and with complete archives and reliable diagnosis of occupational health surveillance. The exclusion criteria of participants were with hypertension at the baseline of study or with heart,liver,kidney diseases and malignant tumors. A total of 12 647 participants were enrolled in this study (11 663 in the exposure group and 984 in the control group). The follow?up period was from January 2006 to December 2017,with a total follow?up of 89 259.75 person?years. Questionnaires and physical measurements were used to collect general demographic characteristics, occupational exposure history and occupational health surveillance data of all participants. The Cox proportional hazards regression model was used to estimate the association between the dust exposure and the incidence of hypertension. Results During the follow?up period, 2 549 new?onset hypertension patients were identified with an incidence density of hypertension about 2 855.71 per 100 000 person?years. The incidence density of hypertension was 2 967.58 per 100 000 person?years in the exposure group, and 1 643.85 per 100 000 person?years in the control group. The results of multivariate Cox proportional hazards regression model showed that after the adjustment of marriage, age, smoking, alcohol drinking and body mass index,the risk of hypertension was higher in the exposure group compared with the control group ( HR=1.692, 95%CI : 1.410-2.032). Further analysis showed that compared with workers from administrative logistics departments,the risk of hypertension in tunneling,mining and auxiliary working was 1.629(1.345-1.973),1.677(1.374-2.046) and 1.782(1.475-2.151),respectively. Conclusion Dust exposure may increase the risk of hypertension in male coal miners.
9.Prophylactic uterine artery chemoembolization combined with sequential ultrasound-guided curettage of uterine cavity for the treatment of cesarean scar pregnancy: clinical observation of 231 patients
Tianhe YE ; Feng PAN ; Guofeng ZHOU ; Bin XIONG ; Chuansheng ZHENG ; Gansheng FENG
Journal of Interventional Radiology 2018;27(2):128-132
Objective To evaluate the clinical application of prophylactic uterine artery chemoembolization (UACE) together with sequential ultrasound-guided curettage of uterine cavity for the treatment of cesarean scar pregnancy (CSP). Methods The clinical data and follow-up results of 231 CSP patients who were treated with UACE together with sequential ultrasound-guided curettage of uterine cavity were retrospectively analyzed. Results After UACE together with sequential ultrasound-guided curettage of uterine cavity, successful termination of pregnancy was achieved in all 231 patients, neither hemorrhagic shock nor death occurred. The median amount of blood loss during curettage of uterine cavity was 10 ml. After curettage of uterine cavity, the median values of RBC, HGB and HCT were 3.53×1012/L, 105 g/L and 32% respectively, the preoperative median values of which were 4.04×1012/L, 121 g/L and 36% respectively, indicating there were a slight reduction in RBC, HGB and HCT after UACE, the differences were statistically significant (P<0.001). The median values of β-HCG measured before UACE and after curettage of uterine cavity were29 069.0 U/ml and 1723.5 U/ml respectively, the difference was statistically significant (P<0.001). According to the gestational age, the patients were divided into group A (gestational age ≤56 days) and group B (gestational age 57-81 days). Further stratified analysis showed that no statistically significant differences in blood loss during curettage of uterine cavity and in reduction degree of RBC, HGB and HCT after UACE existed between group A and group B. Conclusion Prophylactic UACE before CSP can effectively reduce the occurrence of massive bleeding during uterine curettage. For the treatment of CSP, UACE together with sequential ultrasound-guided curettage of uterine cavity is safe and reliable. Therefore, this therapy can be used as a routine treatment strategy for CSP.
10.Effect of aescine sodium combined with albumin treatment in hypertensive cerebral hemorrhage after minimally invasive scavenging surgery
Tao PAN ; Dujuan SHA ; Peng XU ; Qiming LI ; Jun ZHANG ; Guofeng FAN
Chinese Journal of Primary Medicine and Pharmacy 2015;22(1):41-44
Objective To evaluate the effect of aescine sodium combined with albumin in the treatment of hypertensive intracerebral hemorrhage after intracranial hematoma minimally invasive removal surgery.Methods 50 patients with hypertensive intracerebral hemorrhage after intracranial hematoma minimally invasive removal surgery were randomly divided into the two groups:the treatment group was treated with aescine sodium and albumin,the control group was treated with the conventional medical drugs;The neural function defect scale,brain edema area of postoperative patients after 1d and 15d,clinical effects after 15d were observed.Results 15d after operation,in the treatment group,the brain edema area was (2.40 ± 0.32) cm2,neural function defect scale was (9.44 ± 2.25) points,which were better than (3.40 ±0.85) cm2 (t =4.721,P <0.01) and (15.65 ±3.04) points(t =3.625,P <0.01).The total effective rate of the treatment group was 88.9%,which was better than 69.6% of the control group(x2 =13.58,P <0.01).Conclusion Aescine sodium combined with albumin can effectively reduce perihematomal brain edema area,improve nerve function defect and clinical effect in the patients with hypertensive cerebral hemorrhage after minimally invasive scavenging surgery.

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