1.Effect of modified TROPIS operation and open and hanging operation on high anal fistula and its effect on postoperative recovery and function
Changliang CHEN ; Guodan JIANG ; Huifeng LIU ; Xiaojuan ZHOU ; Nan LI
Chinese Journal of Endocrine Surgery 2025;19(1):106-109
Objective:To investigate the effects of modified TROPIS surgery, incorporating both open and hanging stitches on the treatment of elevated anal fistula.Methods:For our study, 92 patients with high anal fistula, admitted between Jan. 2023 and Jun. 2024, were selected. They were divided into two categories: the observation group (45 modified TROPIS surgery) and the control group (47 cuts) ,to observe the clinical efficacy, postoperative recovery, quality of life and complications of the two groups.Results:Compared with the control group, the operation time, intraoperative blood loss and postoperative hospitalization time decreased in the observation group ( P<0.05) . Compared with the control group, the healing time of anal fistula in the observation group was (28.01±5.02) d, shorter than that in the control group (35.05±7.09) d, the healing rate was 97.78%, higher than that in the control group (80.85%) , and the recurrence rate was 4.44%, lower than that in the control group (19.14%) ( P<0.05) . The degree of postoperative pain and Wexner anal incontinence score in the observation group were lower than those in the control group ( P<0.05) . The life quality score of the observation group was higher than that of the control group ( P<0.05) . The complication rate of observation group was lower than that of control group ( P<0.05) . Conclusions:The modified TROPIS surgical method evidently provides advantages in anal fistula treatment. It can not only efficiently eliminate infections but also reduce anal movements and decrease the chances of post-surgical injuries and complications, presenting enhanced clinical options and suggesting a promising outlook for traditional anal fistula surgery.
2.Effect of modified TROPIS operation and open and hanging operation on high anal fistula and its effect on postoperative recovery and function
Changliang CHEN ; Guodan JIANG ; Huifeng LIU ; Xiaojuan ZHOU ; Nan LI
Chinese Journal of Endocrine Surgery 2025;19(1):106-109
Objective:To investigate the effects of modified TROPIS surgery, incorporating both open and hanging stitches on the treatment of elevated anal fistula.Methods:For our study, 92 patients with high anal fistula, admitted between Jan. 2023 and Jun. 2024, were selected. They were divided into two categories: the observation group (45 modified TROPIS surgery) and the control group (47 cuts) ,to observe the clinical efficacy, postoperative recovery, quality of life and complications of the two groups.Results:Compared with the control group, the operation time, intraoperative blood loss and postoperative hospitalization time decreased in the observation group ( P<0.05) . Compared with the control group, the healing time of anal fistula in the observation group was (28.01±5.02) d, shorter than that in the control group (35.05±7.09) d, the healing rate was 97.78%, higher than that in the control group (80.85%) , and the recurrence rate was 4.44%, lower than that in the control group (19.14%) ( P<0.05) . The degree of postoperative pain and Wexner anal incontinence score in the observation group were lower than those in the control group ( P<0.05) . The life quality score of the observation group was higher than that of the control group ( P<0.05) . The complication rate of observation group was lower than that of control group ( P<0.05) . Conclusions:The modified TROPIS surgical method evidently provides advantages in anal fistula treatment. It can not only efficiently eliminate infections but also reduce anal movements and decrease the chances of post-surgical injuries and complications, presenting enhanced clinical options and suggesting a promising outlook for traditional anal fistula surgery.
3.Recurrence prediction model of perianal abscess after incision and drainage was established based on Logistic regression
Nan LI ; Guodan JIANG ; Huifeng LIU
Chinese Journal of Endocrine Surgery 2024;18(6):887-891
Objective:To establish a recurrence prediction model for perianal abscess after incision and drainage surgery based on Logistic regression.Methods:A total of 180 patients with perianal abscess admitted to our hospital from Jan. 2018 to Dec. 2023 were selected as the study objects, all of whom were treated with perianal abscess incision and drainage. According to the follow-up results, the subjects were divided into relapse group and non-recurrence group, and the clinical and follow-up data of the two groups were collected. Multivariate Logistic regression analysis was used to screen the risk factors of postoperative recurrence in patients with perianal abscess. A risk prediction nomogram model was constructed based on the selected risk factors, and the constructed model was evaluated.Results:Of the 180 patients, 35 relapsed during follow-up, with a recurrence rate of 19.44% (35/180). The proportion of patients with diabetes mellitus, abscess site (deep), BMI≥25 kg/m 2, history of chronic diarrhea, and surgical method (simple incision and drainage) in relapse group was higher than that in non-recurrence group ( P<0.05). Combined diabetes mellitus, abscess site (deep), BMI≥25 kg/m 2, history of chronic diarrhea, and surgical method (simple incision and drainage) were the main influencing factors for the recurrence of perianal abscess after incision and drainage. The area under ROC curve (AUC), 95%CI, sensitivity and specificity were 0.873, 0.649-0.996, 96.50% and 79.30% ( P<0.001), respectively, in the prediction of recurrence after incision and drainage of perianal abscess by the nomogram risk model. Calibration curve results showed that both predicted and actual predicted values were near the ideal curve, and the Hosmer-Lemeshow goodness of fit curve test χ 2=3.154, P=0.578. Conclusions:Combined diabetes mellitus, abscess site (deep), BMI≥25 kg/m 2, history of chronic diarrhea, and surgical method (simple incision and drainage) were the main influencing factors for the recurrence of perianal abscess after incision and drainage. The risk prediction model based on the above indexes has good differentiation, calibration and clinical practicability.
4.Recurrence prediction model of perianal abscess after incision and drainage was established based on Logistic regression
Nan LI ; Guodan JIANG ; Huifeng LIU
Chinese Journal of Endocrine Surgery 2024;18(6):887-891
Objective:To establish a recurrence prediction model for perianal abscess after incision and drainage surgery based on Logistic regression.Methods:A total of 180 patients with perianal abscess admitted to our hospital from Jan. 2018 to Dec. 2023 were selected as the study objects, all of whom were treated with perianal abscess incision and drainage. According to the follow-up results, the subjects were divided into relapse group and non-recurrence group, and the clinical and follow-up data of the two groups were collected. Multivariate Logistic regression analysis was used to screen the risk factors of postoperative recurrence in patients with perianal abscess. A risk prediction nomogram model was constructed based on the selected risk factors, and the constructed model was evaluated.Results:Of the 180 patients, 35 relapsed during follow-up, with a recurrence rate of 19.44% (35/180). The proportion of patients with diabetes mellitus, abscess site (deep), BMI≥25 kg/m 2, history of chronic diarrhea, and surgical method (simple incision and drainage) in relapse group was higher than that in non-recurrence group ( P<0.05). Combined diabetes mellitus, abscess site (deep), BMI≥25 kg/m 2, history of chronic diarrhea, and surgical method (simple incision and drainage) were the main influencing factors for the recurrence of perianal abscess after incision and drainage. The area under ROC curve (AUC), 95%CI, sensitivity and specificity were 0.873, 0.649-0.996, 96.50% and 79.30% ( P<0.001), respectively, in the prediction of recurrence after incision and drainage of perianal abscess by the nomogram risk model. Calibration curve results showed that both predicted and actual predicted values were near the ideal curve, and the Hosmer-Lemeshow goodness of fit curve test χ 2=3.154, P=0.578. Conclusions:Combined diabetes mellitus, abscess site (deep), BMI≥25 kg/m 2, history of chronic diarrhea, and surgical method (simple incision and drainage) were the main influencing factors for the recurrence of perianal abscess after incision and drainage. The risk prediction model based on the above indexes has good differentiation, calibration and clinical practicability.
5.Construction and verification of a nomogram model for postoperative recurrence risk in patients with complex anal fistula
Deming YU ; Changliang CHEN ; Honglan SUN ; Huifeng LIU ; Guodan JIANG ; Nan LI
Chinese Journal of Endocrine Surgery 2023;17(6):686-691
Objective:To explore the influencing factors of postoperative recurrence in patients with complex anal fistula, and to construct a nomogram model to predict the risk of postoperative recurrence and verify it.Methods:Clinical data of 310 patients with complex anal fistula who underwent fistulectomy in the hospital from Aug. 2019 to Mar. 2023 were retrospectively selected and divided into modeling group (93 cases) and validation group (217 cases) in a 3∶7 ratio according to system randomization method. Hospital electronic medical record system was used to collect patient baseline data and calculate the recurrence rate of patients 6 months after surgery. According to the data of the modeling group, multivariate Logistic regression was used to analyze the influencing factors of postoperative recurrence in patients with complex anal fistula. Based on the influencing factors, a nomogram model was established to predict the risk of postoperative recurrence, and external verification was performed based on the data of the validation group.Results:The recurrence rate at 6 months after operation was 20.43% (19/93) in the modeling group and 17.51% (38/217) in the validation group. There was no significant difference in recurrence rate between the two groups ( χ2=0.370, P=0.543) . The proportion of male, smoking history, diabetes mellitus, high anal fistula and unclear position of internal orifice in the recurrence group was higher than that in the non-recurrence group, and the body mass index and course of disease were higher than those in the non-recurrence group ( P<0.05) . Based on the above seven influencing factors, a nomogram model of the risk of recurrence of complex anal fistula after surgery was established. C index of the modeling group and the validation group was 0.984 and 0.798 respectively, the calibration curve was close to the ideal curve, and the Receiver operating characteristic AUC of the nomogram prediction model was>0.70, indicating that model consistency, prediction efficiency and differentiation were good. Conclusion:The nomogram prediction model based on gender, body mass index, smoking history, diabetes mellitus, course of disease, high anal fistula and internal orifice position can effectively predict the risk of postoperative recurrence in patients with complex anal fistula.
6.Analysis of application efficiencies of two types of intestinal ostomy in the treatment of elderly obstructive sigmoid colon cancer and colorectal cancer
Nan LI ; Tuo SU ; Guodan JIANG
Chinese Journal of Geriatrics 2017;36(2):177-179
Objectives To study application efficiencies of two types of intestinal ostomy in the treatment of elderly patients with obstructive sigmoid colon cancer and colorectal cancer.Methods 62 elderly patients with obstructive sigmoid colon cancer and rectal cancer from January 2013 to January 2016 in our hospital were chosen.The patients were divided into loop ileostomy group(n=32) and colostomy group(n=30)depending on the type of therapy.And the stage Ⅰ and Ⅱ operative time,hospital stay,postoperative fasting time and postoperative complication incidence rates were compared between the two groups.Results The postoperative fasting time was significantly shorter in loop ileostomy group than in colostomy group during stage Ⅰ surgery(2.5 ± 0.5)d vs.(4.6 ± 0.6)d(t=14.3644,P =0.0000).In stage Ⅱ surgery,the operative time,hospital stay,postoperative fasting time (2.9 ± 0.6)d vs.(4.9 ± 0.4)d,(1.4 ± 0.4)d vs.(2.5 ±± 0.3)d,(6.3± 1.4d)vs.(8.8±1.2)d were significantly lower in the loop ileostomy group than in the colostomy group(t=-15.2762、-10.9714、-7.6601,all P =0.0000).Conclusions Compared with colostomy technique,the loop ileostomy has advantages including shorter operation time,lower incidence of postoperative complications and quicker recovery after surgery for elderly patients with obstructive sigmoid colon cancer and colorectal cancer.
7.Clinical efficacy of two surgical treatment methods for anal fissures in elderly patients
Deming YU ; Guodan JIANG ; Huifeng LIU
Chinese Journal of Geriatrics 2017;36(8):889-891
Objective To compare the clinical efficacy of two surgical methods for the treatment of anal fissures in elderly patients.Methods A total of 138 elderly patients with anal fissures treated at our hospital from January to December 2016 were randomly divided into the conventional method group(69 cases) and the modified method group (69 cases).Patients in the conventional method group were treated with lateral sphincterotomy,while patients in the modified method group were treated with modified longitudinal sphincterotomy with transverse suture.Outcomes of treatment,VAS scores,incision wound infection rates,postoperative voiding dysfunction rates and recurrence rates were compared.Results There was no significant difference in overall effectiveness between the modified method group (98.6%)and the conventional method group(94.2%) (x2=1.8677,P=0.1717).The rates of incision wound infection,moderate postoperative urinary retention and recurrence in the conventional method group(8.7%,42.0% and 10.1 %,respectively)were significantly higher than those in the modified methods group(0.0 %,15.9 % and 0.0%,respectively) (x2 =4.3561,11.4061 and 5.4177,respectively,P =0.0369,0.0007 and 0.0199,respectively).At 12 hours after operation,favorable VAS scores and incision healing times were observed in the modified method group,compared with the conventional method group,and the differences were statistically significant(each P<0.05).Conclusions Modified longitudinal sphincterotomy with transverse suture produces about the same overall effectiveness as does lateral sphincterotomy in the treatment of elderly patients with anal fissures,but it is superior in reducing incision wound infection,moderate postoperative voiding dysfunction,recurrence and pain intensity,and in promoting incision healing.

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