1.Expert consensus on the application of nasal cavity filling substances in nasal surgery patients(2025, Shanghai).
Keqing ZHAO ; Shaoqing YU ; Hongquan WEI ; Chenjie YU ; Guangke WANG ; Shijie QIU ; Yanjun WANG ; Hongtao ZHEN ; Yucheng YANG ; Yurong GU ; Tao GUO ; Feng LIU ; Meiping LU ; Bin SUN ; Yanli YANG ; Yuzhu WAN ; Cuida MENG ; Yanan SUN ; Yi ZHAO ; Qun LI ; An LI ; Luo BA ; Linli TIAN ; Guodong YU ; Xin FENG ; Wen LIU ; Yongtuan LI ; Jian WU ; De HUAI ; Dongsheng GU ; Hanqiang LU ; Xinyi SHI ; Huiping YE ; Yan JIANG ; Weitian ZHANG ; Yu XU ; Zhenxiao HUANG ; Huabin LI
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2025;39(4):285-291
This consensus will introduce the characteristics of fillers used in the surgical cavities of domestic nasal surgery patients based on relevant literature and expert opinions. It will also provide recommendations for the selection of cavity fillers for different nasal diseases, with chronic sinusitis as a representative example.
Humans
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Nasal Cavity/surgery*
;
Nasal Surgical Procedures
;
China
;
Consensus
;
Sinusitis/surgery*
;
Dermal Fillers
2.Clinical analysis of 78 cases of refractory pharyngeal ulcers.
Jingyuan MA ; Guangke WANG ; Jing LI ; Yanzi ZANG
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2025;39(4):362-375
Objective:To explore the clinical characteristics, treatment methods, and prognosis of refractory pharyngeal ulcers. Methods:A retrospective analysis was conducted on the clinical manifestations, laryngoscopic features, laboratory tests, histopathological examinations, and treatments of 78 patients diagnosed with refractory pharyngeal ulcers. Results:There was no significant difference in the proportion of males-to-females in benign lesions, while males were significantly more prevalent in cases of malignant lesions. Seven distinct pathological types of pharyngeal ulcers were identified, with the most common being simple inflammatory ulcers(18 cases), followed by tuberculosis(16 cases), fungi(15 cases), lymphoma(14 cases), squamous cell carcinoma(10 cases), Behcet's disease(3 cases), and myelosarcoma(2 cases). Conclusion:The clinical manifestations and lesions associated with refractory pharyngeal ulcers are diverse. A clear diagnosis should be established based on a systematic and comprehensive medical history, specialized examinations, and additional tests to avoid misdiagnosis and mistreatment. Laryngoscopy and histopathological examinations are essential for identifying the type of lesion and guiding appropriate treatment.
Humans
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Male
;
Female
;
Retrospective Studies
;
Middle Aged
;
Adult
;
Aged
;
Pharyngeal Diseases/pathology*
;
Young Adult
;
Ulcer/pathology*
;
Adolescent
;
Aged, 80 and over
3.Analysis of auditory-vestibular function and inner ear imaging features at different stages of Meniere's disease.
Xin XIN ; Xin MA ; Bowen SUN ; Jun LIU ; Guangke WANG ; Peixia WU
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2025;39(8):724-728
Objective:To explore of auditory-vestibular function and inner ear imaging features of patients with Meniere's disease(MD) at different clinical stages. Methods:The clinical data of 110 patients with unilateral MD who were admitted from January 2023 to March 2024 were collected, and all patients were staged according to the results of pure tone hearing threshold test, including 13 patients with stage Ⅰ, 18 cases with stage Ⅱ, 65 cases with stage Ⅲ, and 14 cases with stage Ⅳ. All patients were tested for vestibular function, including caloric tests, vestibular evoked myogenic potentials(VEMPs), vHIT and sensory integration tests(SOT). The sites of endolymphatic hydrops were evaluated by intravenous endotogidolinium-based MRI, twenty-seven patients completed electrocochleography. Results:①The disease course time of patients with different stages was different, and the disease course time of stage Ⅰ and Ⅱ was shorter than that of stage Ⅲ and Ⅳpatients(P<0.05). ②No statistical differences were found in clinical data or vestibular function between normal and abnormal ECochG groups(P>0.05). ③The results of caloric tests showed that the UW% values of stage Ⅲ(45.5±14.79) and stage Ⅳ (51.57±22.44) were higher than those of stageⅠ(31.2±14.9) and stage Ⅱ(33.5±13.31), there were statistically significant differences between stage Ⅰ and stage Ⅱ with stage Ⅲ and Ⅳ groups(P<0.05), the total abnormal rate of cVEMP was 62.72%, there was a statistically significant difference between stageⅠand stage Ⅲ with the stage Ⅳ group(P<0.05), the total abnormal rate of oVEMP was 71.82%, the difference between stage Ⅰ and stage Ⅳ group was statistically significant(P<0.05). The total score of SOT comprehensive balance gradually decreased with the increase of clinical stage, and there was a significant difference between the stage Ⅰ and Ⅳ groups(H=26.08, P<0.01), and there was a statistically significant difference in the rate of vestibular dysfunction of SOT between the two groups(χ²=6.7, P<0.05). ④Patients with vestibular and cochlear endolymphatic hydrops, and patients with simple cochlear or vestibular had significantly differences in disease course time, clinical stages, UW% value of caloric test, abnormal rate of cVEMP and oVEMP, total SOT balance score, the rate of vestibular abnormality(P<0.01). Among them, when the vestibular and cochlear endolymphatic hydrops are at the same time, the clinical stage of the patient is mainly stage Ⅲand Ⅳ. Conclusion:Auditory-vestibular and inner ear gadolinium-contrasted MRI examinations in clinical practice provide a supplementary reference for judging vestibular function and the type of endolymphatic hydrops.
Humans
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Meniere Disease/diagnostic imaging*
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Ear, Inner/physiopathology*
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Male
;
Magnetic Resonance Imaging
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Female
;
Middle Aged
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Vestibule, Labyrinth/diagnostic imaging*
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Adult
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Vestibular Evoked Myogenic Potentials
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Aged
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Audiometry, Pure-Tone
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Caloric Tests
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Vestibular Function Tests
4. Clinical analysis of 5 cases of dural arteriovenous fistulas complained of pulsatile tinnitus
Xiaodong JIA ; Weixing BAI ; Yunxia GENG ; Guangke WANG ; Shaoguang DING ; Hongjian LIU
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2020;55(1):56-59
Objective:
The clinical characteristics of dural arteriovenous fistula with pulsatile tinnitus were analyzed to deepen the understanding of the disease.
Methods:
The clinical data of five patients complained of pulsatile tinnitus and diagnosed dural arteriovenous fistula in Henan People's Hospital from May 2013 to June 2018 were retrospectively analyzed, including 3 males and 2 females, aged 27-65 years.
Results:
The main clinical symptoms of the five patients were continuous pulsatile tinnitus, accompanied/not accompanied by headache, memory decline, etc., with a course of three months to 20 years. They were diagnosed as dural arteriovenous fistula by digital subtraction angiography, and three cases of tinnitus disappeared and two cases of tinnitus were relieved after embolization.
Conclusions
The dural arteriovenous fistula is a rare and complicated disease. When the patient complain of the pulsatile tinnitus, the related etiology should be considered and managed properly.
5. Analyses of diagnosis and treatment of foreign body aspiration in children with tracheobronchial variations
Weiwei WANG ; Huijuan CHENG ; Meng LI ; Zhihua YIN ; Zhanwei SUN ; Shichao LI ; Tianyi WU ; Guangke WANG
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2019;54(10):760-763
Objective:
To investigate the key issues in the diagnosis and treatment of foreign body aspiration in children with tracheobronchial variations.
Methods:
A retrospective study was performed for 11 pediatric patients who were treated in Department of Otorhinolaryngology and Head and Neck Surgery, Henan Province People′s Hospital after a diagnosis of foreign body aspiration with tracheobronchial variations between January 2015 and December 2017. There were 7 males and 4 females among the 11 cases of foreign body aspiration with tracheobronchial variations, ranging between 9 months and 11 years of age.
Results:
Among 11 cases, the types of variationswere tracheal bronchus in 9 cases, bridging bronchus in 1 case and simple tracheal stenosis in 1 case. All of the pediatric patients were under general anesthesia, and the foreign bodies were removed by bronchoscopy successfully with no significant complications.
Conclusions
The possibility of tracheobronchial variations should be considered in children with recurrent wheezing and poor efficacy of regular treatment before foreign body aspiration. Removal of foreign body via rigid bronchoscope under general anesthesia is a safe and effective treatment. These children are needed to combine the situation oftracheobronchial variations and the location of foreign bodies to guide the operation, and strengthened the perioperative treatment.
7.Application of minimally invasive endoscopic optic nerve decompression in patients with traumatic optic neuropathy
Linggai SHI ; Guangke WANG ; Jun LIU ; Fei LIU ; Shiqing LI
Recent Advances in Ophthalmology 2017;37(7):640-642,646
Objective To analyze the application effects of endoscopic optic nerve decompression in patients with traumatic optic neuropathy and its effect on visual acuity.Methods From January 2014 to January 2016,100 patients (100 eyes) with traumatic optic neuropathy in our hospital were selected as observation objects.According to different treatment methods,the patients were divided into observation group and control group,50 cases in each group.The control group was treated with drugs,and the observation group with endoscopic sinus decompression of optic nerve on the basis of the control group after the stability of the disease.The patients in two groups were followed up at least 1 year.The clinical efficacy,visual acuity,VEP findings and incidence of adverse reactions were compared between the two groups.Results The effective rates in the observation group and control group were 76.0% and 36.0%,there was significant difference between two groups (P < O.05).In the observation group,the visual acuity of 16 eyes were improved in 22 eyes with no light perception,9 eyes in 13 eyes with light perception,9 eyes in 11 eyes with hand movement,and 4 eyes with finger counting were all improved;In the control group,the visual acuity of 6 eyes were improved in 20 eyes with no light perception,6 eyes in 14 eyes with light perception,5 eyes in 12 eyes with hand movement,1 eye in 4 eyes with finger counting.After treatment,the incubation period and amplitude of P1O0 in the observation group were (116.85 ±7.96) ms and (5.11 ± 1.16) μV,which were better than the control group (105.62 ±6.82) ms,(4.31 ± 1.25) μV.The incidence of adverse reaction in the observation group was significantly lower than that in the control group (P =O.000).Conclusion The endoscopic optic nerve decompression has a good application effect and safety in patients with traumatic optic neuropathy,can effectively improve the patient's visual acuity,help to improve the quality of life of patients,is worthy of clinical application.
9.Effect of Ipratropium bromide combined with atomization inhalation of budesonide on acute exacerbation of chronic obstructive pulmonary disease
Yuliang ZHAO ; Guangke CAO ; Zhihai LI ; Yingjun SHI ; Wang ZHU ; Ge YANG ; Fanying MENG
Chinese Journal of Geriatrics 2015;34(7):726-727
Objective To assess the clinical efffects off Ipratropium bromide combined with atomization inhalation of budesonide via a ventilator with a Y-shaped connector on acute exacerbation off chronic obstructive pulmonary disease (AECOPD).Methods A total off 62 AECOPD patients treated at our hospital from June 2013 to September 2014 were randomly divided into the experimental group (n=31,treated with ipratropium bromide combined with atomization inhalation of budesonide) and the control group (n =31,treated with the same amount of saline).Results The airway pressure of mechanical ventilation,the time of mechanical ventilation and the time of staying in the intensive care unit all showed significant differences between the experimental and control groups [(25.4±5.2) cmH2O vs.(38.1±3.4) cmH2O,(6.5±1.3) d vs.(6.8±1.4) d,(8.9±2.1) d vs.(9.5±1.5) d,t=10.934,0.960,1.108,respectively,P<0.05 for all].The rate of tracheotomy was lower in the experimental group than in the control group (17/31 or 54.8% vs.20/31 or 64.5%,x2 =0.603,P<0.05).Conclusions Ipratropium bromide combined with budesonide inhalation under mechanical ventilation via a Y-shaped connector has ffavorable clinical effects on AECOPD.
10.Efficacy and risk factors of revision endoscopic sinus surgery
Zhihua YIN ; Guangke WANG ; Hongjian LIU
Chinese Archives of Otolaryngology-Head and Neck Surgery 2015;(11):581-584
[ABSTRACT]OBJECTIVETo analyze the risk factors and clinical curative effect of revision endoscopic sinus surgery.METHODSThe clinical data of the 80 patients underwent revision endoscopic sinus surgery were analyzed and the efficacy of the surgery was evaluated by the scores of the endoscopic examination, Lund-Mackay and VAS scoring system. Recovery rate and risk factors were observed and assessed. RESULTSIn 80 patients, 62 cases recovered, 11 cases improved, 7 cases were ineffective,and the total effective rate was 91.25%. Single factor analysis showed that operation frequency, follow-up compliance, history of allergic rhinitis and polyps effect on the clinical curative effect significantly (P<0.05). Multiple Logistic regression analysis showed that main risk factors affecting the curative effect were operation frequency, history of allergic rhinitis and polyps, follow-up compliance, VAS score, endoscopic examination scores, CT examination score, and nasal cavity adhesion (relative risk was between 1.4-2.8).CONCLUSIONOperation frequency, follow-up compliance, history of allergic rhinitis and polyps are important factors on curative effect of revision surgery.

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