Background::Carbon monoxide (CO) poisoning remains a major cause of accidental injuries and multiple studies have indicated that CO is also associated with significantly severe or long-term toxicity to the central nervous system. Given that CO poisoning causes serious morbidity and mortality, a better understanding of epidemiological features and clinical characteristics of acute CO poisoning in China is crucial.Methods::We collected the clinical data of acute CO poisoning in patients between November 2019 and April 2020 across Shandong province, China and analyzed its characteristics focusing on the weekly amount and the severity of the confirmed cases.Results::A total number of 21,088 acute CO poisoning cases were diagnosed. The overall incidence of acute CO poisoning was approximately 0.021%. On severity rankings, 63% of confirmed cases ( n = 13,378) were mild, 27% (n = 5635) were moderate, and 10% ( n = 2075) were severe. Interestingly, the coastal cities had more confirmed cases than the inland/suburban areas in Shandong. Meanwhile, the number of confirmed cases was negatively correlated with the local mean daily temperature ( P = 0.0167). Conclusions::Mild acute CO poisoning cases accounted for the majority of all confirmed cases during the winter of 2019. In Shandong province, which is located in east China, residents of the coastal cities are more susceptible to CO poisoning than residents of inland cities.

Objective:To improve the understanding of the clinical characteristics and diagnosis of acute aortic dissection (AAD) in pilots.Methods:This paper reported the clinical features, predisposing factors, diagnosis and treatment of a helicopter pilot with aortic dissection. The related literatures were reviewed.Results:The pilot was a 32-year-old male who denied a history of hypertension and presented with persistent severe chest pain. CT angiography of the aorta suggested thoracic-abdominal aortic dissection. Strict bed rest, blood pressure control and thoracic endovascular aortic repair were performed one week after the diagnosis. There were no abnormalities in limb activity, renal function, gastrointestinal function, electrocardiogram and transthoracic echocardiography after endovascular intervention. The pilot was finally disqualified in aviation.Conclusions:Aortic dissection is extremely rare in pilots and should be carefully considered in the diagnosis of chest pain. During the pilot recruiting process and the practice of flight surgeon, more attention should be paid on the possibility of such rare disease as aortic dissection in case of the symptoms of chest pain appeared.

Objective:To improve the understanding of the clinical characteristics and diagnosis of acute aortic dissection (AAD) in pilots.Methods:This paper reported the clinical features, predisposing factors, diagnosis and treatment of a helicopter pilot with aortic dissection. The related literatures were reviewed.Results:The pilot was a 32-year-old male who denied a history of hypertension and presented with persistent severe chest pain. CT angiography of the aorta suggested thoracic-abdominal aortic dissection. Strict bed rest, blood pressure control and thoracic endovascular aortic repair were performed one week after the diagnosis. There were no abnormalities in limb activity, renal function, gastrointestinal function, electrocardiogram and transthoracic echocardiography after endovascular intervention. The pilot was finally disqualified in aviation.Conclusions:Aortic dissection is extremely rare in pilots and should be carefully considered in the diagnosis of chest pain. During the pilot recruiting process and the practice of flight surgeon, more attention should be paid on the possibility of such rare disease as aortic dissection in case of the symptoms of chest pain appeared.

Objective To study the protective effect of compound raspberry seed powder on acute irradiated rat .Methods Totally forty Wistar rats were randomized divided into four groups:normal control group, radiation group, vitamin group, compound raspberry seed powder group . The drugs were intragastrically administrated for 7 days.On 8th day, the rats in each group except control were irradiated with 8 Gy X-rays.24 h after irradiation, all rats were sacrificed and its WBC, PLT, superoxide dismutases (SOD), malonaldehyde (MDA), glutathione peroxidase (GSH-PX) in serum were detected, the DNA damage in peripheral blood lymphocytes ( PBL ) was measured with the single cell gel electrophoresis technique.Results Compared with radiation alone group , the quantities of WBC, PLT, the activity of SOD, the content of MDA and the activity of GSH-PX in the vitamin group and compound raspberry seed powder group were significantly improved(F=14.869, 6.376, 7.705, 3.851, 3.134, P<0.05).The DNA damage in PBL of radiation alone group was more severe than that of other three groups ( F=5.493, P<0.05) .Conclusions Raspberry seed powder is effective in radiation protection .

Objective To compare the CT changes in lungs among mechanically-ventilated dogs before and after a single hyperbaric oxygen exposure,and investigate the effects of HBO on lungs.Methods Forty healthy adult dogs were randomly divided into 4 groups:the hyperbaric oxygen (HBO) group,the normabaric oxygen (NBO) group,the hyperbaric air group and the normabaric air group.All the dogs were mechanically ventilated and CT scan on lungs were taken before and after the session to compare the CT value by Picture Archiving and Communication System on different lung parts.Results There was no significant difference between all the groups of apical and median fields of lung CT values (P ＞ 0.05).In HBO and NBO groups,deficiency of pulmonary aeration developed preferentially in caudal lung fields.Compared with the NBO group,the changes of HBO group were more dramatic.There were significant differences in CT values between HBO and NBO groups(P ＜0.05).Conclusions Compared with NBO,ventilating at 0.2 MPa caused much more significant deficient aerations of the lungs.

Objective To compare the CT changes in lungs among mechanically-ventilated dogs before and after a single hyperbaric oxygen exposure,and investigate the effects of HBO on lungs.Methods Forty healthy adult dogs were randomly divided into 4 groups:the hyperbaric oxygen (HBO) group,the normabaric oxygen (NBO) group,the hyperbaric air group and the normabaric air group.All the dogs were mechanically ventilated and CT scan on lungs were taken before and after the session to compare the CT value by Picture Archiving and Communication System on different lung parts.Results There was no significant difference between all the groups of apical and median fields of lung CT values (P ＞ 0.05).In HBO and NBO groups,deficiency of pulmonary aeration developed preferentially in caudal lung fields.Compared with the NBO group,the changes of HBO group were more dramatic.There were significant differences in CT values between HBO and NBO groups(P ＜0.05).Conclusions Compared with NBO,ventilating at 0.2 MPa caused much more significant deficient aerations of the lungs.