OBJECTIVES: To report the development, validation, and findings of the Multi-dimensional Attention Rating Scale (MARS), a self-report tool crafted to evaluate six-dimension attention levels. METHODS: The MARS was developed based on Classical Test Theory (CTT). Totally 202 highly educated healthy adult participants were recruited for reliability and validity tests. Reliability was measured using Cronbach's alpha and test-retest reliability. Structural validity was explored using principal component analysis. Criterion validity was analyzed by correlating MARS scores with the Toronto Hospital Alertness Test (THAT), the Attentional Control Scale (ACS), and the Attention Network Test (ANT). RESULTS: The MARS comprises 12 items spanning six distinct dimensions of attention: focused attention, sustained attention, shifting attention, selective attention, divided attention, and response inhibition.As assessed by six experts, the content validation index (CVI) was 0.95, the Cronbach's alpha for the MARS was 0.78, and the test-retest reliability was 0.81. Four factors were identified (cumulative variance contribution rate 68.79%). The total score of MARS was correlated positively with THAT (r = 0.60, P < 0.01) and ACS (r = 0.78, P < 0.01) and negatively with ANT's reaction time for alerting (r = -0.31, P = 0.049). CONCLUSIONS The MARS can reliably and validly assess six-dimension attention levels in real-world settings and is expected to be a new tool for assessing multi-dimensional attention impairments in different mental disorders.
Humans ; Adult ; Male ; Attention/physiology* ; Female ; Middle Aged ; Reproducibility of Results ; Young Adult ; Psychometrics

The typical regions have established a coordinated chronic disease management organization system,promoted the coordinated management of health care,medical,and medicine systems,optimized the chronic disease service process,and empowered the grassroots through information technology construction.It has achieved different degrees of results in controlling the condition of patients,reducing the hospitalization rate and the level of medical expenses of patients with chronic diseases,and saving medical insurance funds.

Hospitals without disciplines have no performance performance,the focus of performance reform lies in mechanism transformation.Hospital performance management and discipline construction are interdependent relationships.Performance management provides guidance and motivation for the process of discipline construction,the construction of disciplines provides a value basis for the business connotation of performance management.Guiding discipline construction by clarifying the disease efficacy system.Clarify discipline construction by refining the technical system.Quantify discipline construction by organizing departmental projects.Transform financial and personnel performance assessment into technical value management.The conjugate mechanism can trigger and drive the deployment,support,and fulfillment of business.Performance management plans are only effective when they are publicly available.Only solutions that comply with business logic can be made public.By mining valuable data,we tap into potential business value.

Background and objective Isoliquiritigenin(ISL)is an important pharmacological constituent of Glycyrrhiza glabra,which possesses a range of physiological and pharmacological activities,as well as significant antitumor ac-tivity,and can be used as a potential drug for targeted cancer therapy.LINC01503 is an oncogene,which has been closely asso-ciated with the malignant biological processes of many cancers.The aim of this study was to investigate the effects of ISL on the proliferation,apoptosis,invasion and migration oflung squamous carcinoma cells by regulating LINC01503.Methods Plasma was collected from lung squamous carcinoma patients and healthy individuals treated at Tangshan People's Hospital from Janu-ary 2021 to December 2022.The expression of LINC01503 in lung squamous carcinoma plasma,tissues and cells was detected by real-time quantitative fluorescence polymerase chain reaction(qRT-PCR).Lung squamous carcinoma cells were treated with different concentrations of ISL for 24 h,and LINC01503 expression was detected by qRT-PCR.The cells were treated in groups:si-NC group,si-LINC01503 group,DMSO(0.1％dimethyl sulfone)group,ISL group,pc DNA3.1(+)-NC group,pc DNA3.1(+)-LINC01503 group,ISL+pc DNA3.1(+)-NC group and ISL+pc DNA3.1(+)-LINC01503 groups.CCK-8 assay,clone formation assay,flow cytometry,Transwell assay and scratch assay were used to explore the effect of LINC01503 on the functional phenotype of lung squamous carcinoma cells.Results Fluorescence in situ hybridization results showed that the average fluorescence intensity of LINC01503 in tissue microarrays of lung squamous carcinoma patients was higher than that in paracancerous tissues(P＜0.05).The expression of LINC01503 in the plasma of patients with lung squamous carcinoma was higher than that in the plasma of healthy individuals(P＜0.05).Knockdown of LINC01503 inhibited the proliferation,invasion and migration of lung squamous carcinoma cells and promoted apoptosis(P＜0.05).ISL inhibited the proliferation,invasion,migration and promoted apoptosis of lung squamous carcinoma cells(P＜0.05).Overexpression of LINC01503 followed by intervention with ISL reversed the promotional effect of overexpression of LINC01503 on the proliferation,invasion and migration of lung squamous carcinoma cells as well as the inhibitory effect on apoptosis(P＜0.05).Conclusion LINC01503 was highly expressed in lung squamous carcinoma,and LINC01503 could promote the proliferation,invasion and migra-tion of lung squamous carcinoma cells and inhibit the apoptosis,ISL could inhibit the proliferation,invasion and migration of lung squamous carcinoma cells and promote apoptosis of lung squamous carcinoma cells by regulating the expression of LINC01503.

Synergistic development and governance among medical services,medical insurance and medicines are crucial for achieving high-quality healthcare and successful healthcare system reform.It systematically analyzes and summarizes Dongtai City's practice on synergistic development and governance among medical services,medical insurance and medicines,highlighted by the reform experiences and measures of the closed-loop system,including strategic design(navigator),leadership for organizing(engine),integration of resources(fuel tank),coordinating instruments(lubricant),and evaluation and feedback(barometer),which are refined into the SLICE model for synergistic development and governance of the"three medical professions".It also proposes to stimulate synergistic governance on healthcare through reform and innovation,fully leveraging the leading role of Party committees and governments at all levels and establishing a cross-departmental deliberative and coordination mechanism for synergistic healthcare governance.It aims to engage diverse stakeholders in synergistic governance and strengthen systematic synergistic governance measures to ensure that the synergistic development of the"three medical professions"and governance reforms are on a steady course.

Synergistic development and governance among medical services,medical insurance and medicines are crucial for achieving high-quality healthcare and successful healthcare system reform.It systematically analyzes and summarizes Dongtai City's practice on synergistic development and governance among medical services,medical insurance and medicines,highlighted by the reform experiences and measures of the closed-loop system,including strategic design(navigator),leadership for organizing(engine),integration of resources(fuel tank),coordinating instruments(lubricant),and evaluation and feedback(barometer),which are refined into the SLICE model for synergistic development and governance of the"three medical professions".It also proposes to stimulate synergistic governance on healthcare through reform and innovation,fully leveraging the leading role of Party committees and governments at all levels and establishing a cross-departmental deliberative and coordination mechanism for synergistic healthcare governance.It aims to engage diverse stakeholders in synergistic governance and strengthen systematic synergistic governance measures to ensure that the synergistic development of the"three medical professions"and governance reforms are on a steady course.

Synergistic development and governance among medical services,medical insurance and medicines are crucial for achieving high-quality healthcare and successful healthcare system reform.It systematically analyzes and summarizes Dongtai City's practice on synergistic development and governance among medical services,medical insurance and medicines,highlighted by the reform experiences and measures of the closed-loop system,including strategic design(navigator),leadership for organizing(engine),integration of resources(fuel tank),coordinating instruments(lubricant),and evaluation and feedback(barometer),which are refined into the SLICE model for synergistic development and governance of the"three medical professions".It also proposes to stimulate synergistic governance on healthcare through reform and innovation,fully leveraging the leading role of Party committees and governments at all levels and establishing a cross-departmental deliberative and coordination mechanism for synergistic healthcare governance.It aims to engage diverse stakeholders in synergistic governance and strengthen systematic synergistic governance measures to ensure that the synergistic development of the"three medical professions"and governance reforms are on a steady course.

Synergistic development and governance among medical services,medical insurance and medicines are crucial for achieving high-quality healthcare and successful healthcare system reform.It systematically analyzes and summarizes Dongtai City's practice on synergistic development and governance among medical services,medical insurance and medicines,highlighted by the reform experiences and measures of the closed-loop system,including strategic design(navigator),leadership for organizing(engine),integration of resources(fuel tank),coordinating instruments(lubricant),and evaluation and feedback(barometer),which are refined into the SLICE model for synergistic development and governance of the"three medical professions".It also proposes to stimulate synergistic governance on healthcare through reform and innovation,fully leveraging the leading role of Party committees and governments at all levels and establishing a cross-departmental deliberative and coordination mechanism for synergistic healthcare governance.It aims to engage diverse stakeholders in synergistic governance and strengthen systematic synergistic governance measures to ensure that the synergistic development of the"three medical professions"and governance reforms are on a steady course.

Synergistic development and governance among medical services,medical insurance and medicines are crucial for achieving high-quality healthcare and successful healthcare system reform.It systematically analyzes and summarizes Dongtai City's practice on synergistic development and governance among medical services,medical insurance and medicines,highlighted by the reform experiences and measures of the closed-loop system,including strategic design(navigator),leadership for organizing(engine),integration of resources(fuel tank),coordinating instruments(lubricant),and evaluation and feedback(barometer),which are refined into the SLICE model for synergistic development and governance of the"three medical professions".It also proposes to stimulate synergistic governance on healthcare through reform and innovation,fully leveraging the leading role of Party committees and governments at all levels and establishing a cross-departmental deliberative and coordination mechanism for synergistic healthcare governance.It aims to engage diverse stakeholders in synergistic governance and strengthen systematic synergistic governance measures to ensure that the synergistic development of the"three medical professions"and governance reforms are on a steady course.

Synergistic development and governance among medical services,medical insurance and medicines are crucial for achieving high-quality healthcare and successful healthcare system reform.It systematically analyzes and summarizes Dongtai City's practice on synergistic development and governance among medical services,medical insurance and medicines,highlighted by the reform experiences and measures of the closed-loop system,including strategic design(navigator),leadership for organizing(engine),integration of resources(fuel tank),coordinating instruments(lubricant),and evaluation and feedback(barometer),which are refined into the SLICE model for synergistic development and governance of the"three medical professions".It also proposes to stimulate synergistic governance on healthcare through reform and innovation,fully leveraging the leading role of Party committees and governments at all levels and establishing a cross-departmental deliberative and coordination mechanism for synergistic healthcare governance.It aims to engage diverse stakeholders in synergistic governance and strengthen systematic synergistic governance measures to ensure that the synergistic development of the"three medical professions"and governance reforms are on a steady course.