Patient cancer care education aims to inform and empower patients by providing clear, relevant information about cancer, including its mechanisms, treatment options, and management strategies. This study evaluated the effectiveness and accuracy of existing patient cancer care education materials in Malaysia, specifically assessing patients’ understanding of treatment, side effects, and their management. Method: A descriptive, correlational study was conducted involving 20 cancer patients at Gleneagles Penang Medical Center, using the Patient Cancer Education Needs Assessment questionnaire. Data analysis was performed using SPSS version 21.0 and Microsoft Excel 2013. Result: Patient age, education level, occupation, and socioeconomic status were not significant factors influencing understanding. Findings highlight the need to improve existing educational materials to enhance patient comprehension and ensure materials are comprehensive, culturally appropriate, and innovative. Conclusion: Patient cancer care education materials should be comprehensive, interactive, and patient is friendly. Current materials require revision and enhancement to keep pace with technological developments, ensuring they are accessible, understandable, and effective in supporting patients’ knowledge of cancer treatment, side effects, management strategies, and psychosocial aspects.

Background: Obesity complicates open kidney transplantation (OKT), driving increasing interest in robot-assisted kidney transplantation (RAKT). This study compared intraoperative and postoperative outcomes of RAKT and OKT in patients with a body massindex ≥30 kg/m². Methods: Systematic searches of PubMed, Scopus, and the Cochrane Library were conducted through April 15, 2025. Four retrospective cohort studies (147 RAKT and 625 OKT cases) met the inclusion criteria. Pooled analyses evaluated cold and warm ischemia times, estimated blood loss, estimated glomerular filtration rate (eGFR) at 6 months and 1 year, serum creatinine at 6 months and 3 years, delayed graft function (DGF), graft survival at 1 and 3 years, length of stay, rejection rate, 1-year patient survival, and surgical site infection (SSI) using a random-effects model. Results: No significant differences were observed in cold ischemia time (mean difference [MD], 43.88 minutes; 95% confidence interval [CI], –88.06 to 175.82 minutes;P=0.51), warm ischemia time (MD, 3.21 minutes; 95% CI, –3.23 to 9.65 minutes; P=0.33), or estimated blood loss (MD, –41.30 mL; 95% CI, –95.60 to 12.99 mL; P=0.14). Other postoperative outcomes, including graft function (eGFR and creatinine), DGF, hospital stay, rejection, and 1-year survival, were also comparable. However, RAKT was associated with a significantly lower SSI incidence (risk ratio, 0.14; 95% CI, 0.04–0.45;P=0.0009). Conclusions In obese patients, RAKT yields outcomes comparable to OKT, with the added potential benefit of reducing SSI risk. Nonetheless, as most findings are based on very low-certainty evidence, these results should be interpreted with caution. Larger randomized trials are required to confirm these outcomes.

Pengenalan: Soal selidik sebagai alat untuk mengukur faktor sosiobudaya berkaitan COVID-19 masih belum digunakan secara meluas oleh kebanyakan penyelidik. Di Malaysia, tiada soal selidik yang dibina dan disahkan untuk tujuan tersebut. Oleh itu, tujuan kajian ini adalah untuk membina dan mengesahkan soal selidik sebagai alat ujian yang baru bagi mengukur faktor sosiobudaya berkaitan COVID-19 dalam kalangan Orang Asli di Malaysia. Metodologi: Kajian rintis ini melibatkan 30 orang penduduk Orang Asli di Pos Lenjang, Kuala Lipis, Pahang. Indeks Kesahan Kandungan (CVI) digunakan untuk menguji kesahan kandungan soal selidik, manakala kesahan konstruk dan kebolehpercayaan konsistensi dalaman soal selidik ditentukan menggunakan Exploratory factor analysis (EFA) dan Cronbach’s Alpha. Hasil Kajian: Satu set soal selidik terdiri daripada empat konstruk telah dibina iaitu kepercayaan, amalan perubatan tradisional, adat dan budaya tradisional, dan sokongan sosial. Sebanyak 16 item telah dikekalkan di dalam EFA dengan nilai Cronbach’s Alpha setiap konstruk adalah 0.617, 0.778, 0.773 dan 0.779. Rumusan Soal selidik yang telah dibina ini berjaya divalidasi dan boleh digunakan untuk mengukur faktor sosiobudaya berkaitan COVID-19 dalam kalangan Orang Asli. Walau bagaimanapun, penambahbaikan masih perlu dilakukan dari masa ke semasa untuk memastikan soal selidik ini relevan terutamanya jika ia digunakan ke atas populasi atau dari negara yang berbeza dari Malaysia, dengan mengambil kira juga penyakit yang berbeza.

Wound healing is a complex process that includes haemostasis and inflammation, followed by a proliferation period and repair and finally remodelling. Ocular surgeries, particularly in glaucoma cases, aim at minimal fibrosis to preserve the function of trabeculectomy as an alternative pathway for aqueous drainage. Hence, it is important to find an agent to modulate the wound healing process. This review presents compilation of wound modulation agents that have been tested in vitro, in vivo, or clinically on patients undergoing ocular surgeries, particularly for glaucoma. We identified agents into four groups, mostly for glaucoma filtration operations: anti-metabolites, anti-growth factors, mechanical barriers and rho kinases. The effect of these agents is highlighted in this review. In conclusion, despite recognized drawbacks of antimetabolites, they are still regarded as the gold standard and the most efficient treatment as anti-scarring agents use in ocular surgeries. More studies are needed to inquire agents that efficient yet has minimal adverse effects both in short and long term.

Background: The diagnosis of thyroid neoplasms necessitates the identification of distinct histological features. Various education/hospital centers located in cities across Indonesia likely result in discordances among pathologists when diagnosing thyroid neoplasms. Methods: This study examined the concordance among Indonesian pathologists in assessing nuclear features and capsular and vascular invasion of thyroid tumors. Fifteen pathologists from different centers independently assessed the same 14 digital slides of thyroid tumor specimens. All the specimens were thyroid neoplasms with known BRAFV600E and RAS mutational status, from a single center. We evaluated the pre- and post-training agreement using the Fleiss kappa. The significance of the training was evaluated using a paired T-test. Results: Baseline agreement on nuclear features was slight to fair based on a 3-point scoring system (k = 0.14 to 0.28) and poor to fair based on an eight-point system (k = –0.02 to 0.24). Agreements on vascular (κ = 0.35) and capsular invasion (κ = 0.27) were fair, whereas the estimated molecular type showed substantial agreement (κ = 0.74). Following the training, agreement using the eight-point system significantly improved (p = 0.001). Conclusions The level of concordance among Indonesian pathologists in diagnosing thyroid neoplasm was relatively poor. Consensus in pathology assessment requires ongoing collaboration and education to refine diagnostic criteria.

Background: The diagnosis of thyroid neoplasms necessitates the identification of distinct histological features. Various education/hospital centers located in cities across Indonesia likely result in discordances among pathologists when diagnosing thyroid neoplasms. Methods: This study examined the concordance among Indonesian pathologists in assessing nuclear features and capsular and vascular invasion of thyroid tumors. Fifteen pathologists from different centers independently assessed the same 14 digital slides of thyroid tumor specimens. All the specimens were thyroid neoplasms with known BRAFV600E and RAS mutational status, from a single center. We evaluated the pre- and post-training agreement using the Fleiss kappa. The significance of the training was evaluated using a paired T-test. Results: Baseline agreement on nuclear features was slight to fair based on a 3-point scoring system (k = 0.14 to 0.28) and poor to fair based on an eight-point system (k = –0.02 to 0.24). Agreements on vascular (κ = 0.35) and capsular invasion (κ = 0.27) were fair, whereas the estimated molecular type showed substantial agreement (κ = 0.74). Following the training, agreement using the eight-point system significantly improved (p = 0.001). Conclusions The level of concordance among Indonesian pathologists in diagnosing thyroid neoplasm was relatively poor. Consensus in pathology assessment requires ongoing collaboration and education to refine diagnostic criteria.

Background: The diagnosis of thyroid neoplasms necessitates the identification of distinct histological features. Various education/hospital centers located in cities across Indonesia likely result in discordances among pathologists when diagnosing thyroid neoplasms. Methods: This study examined the concordance among Indonesian pathologists in assessing nuclear features and capsular and vascular invasion of thyroid tumors. Fifteen pathologists from different centers independently assessed the same 14 digital slides of thyroid tumor specimens. All the specimens were thyroid neoplasms with known BRAFV600E and RAS mutational status, from a single center. We evaluated the pre- and post-training agreement using the Fleiss kappa. The significance of the training was evaluated using a paired T-test. Results: Baseline agreement on nuclear features was slight to fair based on a 3-point scoring system (k = 0.14 to 0.28) and poor to fair based on an eight-point system (k = –0.02 to 0.24). Agreements on vascular (κ = 0.35) and capsular invasion (κ = 0.27) were fair, whereas the estimated molecular type showed substantial agreement (κ = 0.74). Following the training, agreement using the eight-point system significantly improved (p = 0.001). Conclusions The level of concordance among Indonesian pathologists in diagnosing thyroid neoplasm was relatively poor. Consensus in pathology assessment requires ongoing collaboration and education to refine diagnostic criteria.