1.Investigating the effects of age, body composition, and breast morphology on mammographic imaging
Tugsjargal P ; Dariimaa G ; Erdembileg Ts ; Enebish S ; ; Tuvshinjargal D
Mongolian Journal of Health Sciences 2026;96(6):228-232
Background:
Although breast density is an important determinant of breast cancer risk and the likelihood of masking pathological lesions on mammography, it is insufficient to fully characterize the breast imaging phenotype on its own. Age, body mass index (BMI), total body fat percentage, breast size, compressed breast thickness, tissue distribution, and reproductive history influence not only the biological composition of the breast but also the technical conditions of mammographic imaging.
Aim:
To synthesize the evidence on how age, BMI, body composition, breast-specific anthropometric characteristics, reproductive factors, and population-specific characteristics influence mammographic imaging.
Materials and Methods:
In this review, we synthesized evidence from studies indexed in PubMed/MEDLINE, Scopus, Embase, and Web of Science from 2000 through August 2026, focusing on the associations of these factors with mammographic appearance, lesion conspicuity, BI-RADS classification, image quality, radiation dose, and screening performance.
Result:
Breast density generally decreases with advancing age and during the menopausal transition. Increasing BMI and adipose tissue volume are also associated with lower breast tissue density. Therefore, the absolute volume of fibroglandular and connective tissue should not be inferred directly from percent breast density alone. Breast-specific parameters, particularly compressed breast thickness and breast volume, are clinically important because they influence positioning, compression, exposure parameters, and mean glandular dose. Studies in Asian cohorts have demonstrated significant associations between age, body size, and mammographic characteristics, although substantial inter-population differences have been reported. Advances in digital breast tomosynthesis (DBT) and artificial intelligence (AI) are enabling a transition from single-category breast density assessment toward multidimensional breast phenotyping. Future research should integrate DICOM technical parameters, standardized anthropometric measurements, quantitative breast density measures, and externally validated AI-derived features to improve personalized screening and radiation dose optimization.
Conclusion
Breast imaging phenotype should be considered a multidimensional construct integrating breast density with age, body composition, breast spatial architecture, imaging parameters, and validated AI-derived features. This approach may improve biological interpretation, radiation dose estimation, and risk stratification while avoiding the oversimplification that a single breast-density percentage or BI-RADS density category can fully characterize the breast phenotype.
2.Correlation of Patterns of Mammographic changes and BI-RADS Assessment
Tugsjargal P ; Dariimaa G ; Erdembileg Ts ; Enebish S ; ; Tuvshinjargal D
Mongolian Journal of Health Sciences 2026;97(7):88-93
Background:
Although breast cancer incidence is rising in Mongolia, little is known about how mammographic findings and BI-RADS final assessment categories are recorded in routine clinical practice.
Aim:
To describe report-derived finding categories and BI-RADS final assessments in a single-centre mammography registry, and to examine the association of age with BI-RADS ≥3.
Materials and Methods:
In this retrospective analytical cross-sectional analysis of 773 mammographic examination records, the earliest examination per participant was retained, yielding 733 women aged 20–74 years. Free-text findings were assigned to mutually exclusive categories using prespecified hierarchical keyword rules, and BI-RADS categories 3 and 4 were combined as “BI-RADS ≥3”. Group differences were examined with Pearson’s χ² test and the age association with logistic regression; a body mass index (BMI)-adjusted model was fitted in 258 women with recorded height and weight.
Results:
Mean age was 44.2±10.8 years. The most frequent report categories were no lesion (28.4%), calcification (20.1%), density-related descriptors (19.8%) and other benign/structural findings (16.0%). BI-RADS categories 1, 2, 3 and 4 were recorded in 312 (42.6%), 342 (46.7%), 65 (8.9%) and 14 (1.9%) women, respectively, and BI-RADS ≥3 in 79 (10.8%; 95% CI 8.7–13.2). This proportion differed across age groups (χ²=12.72; P=0.026). Each additional decade of age was associated with higher odds of BI-RADS ≥3 (OR 1.44; 95% CI 1.16–1.79; P=0.001), and the association persisted after BMI adjustment (OR 1.62; 95% CI 1.10–2.36; P=0.013). BMI was not associated with BI-RADS ≥3.
Conclusions
1. Among the 733 women examined at a single hospital, the most common mammographic findings were no significant abnormalities (28.4%), calcifications (20.1%), density-related findings (19.8%), and other benign or structural changes (16.0%). 2. Of the final assessments, 89.2% were classified as BI-RADS 1–2, while 10.8% were classified as BI-RADS 3–4. No cases were classified as BI-RADS 0 or BI-RADS 5. 3. For every 10-year increase in age, the odds of receiving a BI-RADS score of ≥3 increased by a factor of 1.44. This association remained independent of body mass index (BMI).
3.First case of endovascular surgery with rotablation
Lhagvasuren Z ; Baasanjav N ; Batmyagmar Kh ; Narantuya D ; Erdembileg D ; Batzaya Ts ; Gereltuya Ch
Mongolian Medical Sciences 2020;191(1):96-99
Introduction
In 1987 Jerome Ritchie, David Auth and colleagues first introduced rotational atherectomy (rotablation)
as a technique for the endovascular treatment of obstructive atherosclerotic disease. Rotational
atherectomy covers 3-5% of all procedures in big PCI centers, while <1% in smaller centers. By
study of Warth DC et al. in 1994, at early period when it was first introduced, procedure complication
of rotablation was about 40%, those with coronary dissection 29%, coronary artery occlusion 11.2%,
side branch occlusion 1.8%, distal occlusion 0.9%, no relow phenomenon 6.1%, severe vasospasm
13.8% and vascular perforation 1-2%.
By advanced techniques and technologies that kind of complications reduced significantly, it occurs
as same as other PCI procedures.
In our country PCI procedure was first introduced in Third State Central Hospital in 2000, since then
20 years has passed. During this period coronary intravascular diagnosis and treatment developed
progressively performing 14751 PTCA procedures, of those 8355(56,6%) PCI cases. By statistics
of 2017, myocardial infarction occurred 1145.6 in 10000 population, showing sharp increase, and
cardiovascular mortality became number one cause and has tendency to increase further.
To inform first outcome of rotational atherectomy of atherosclerosis that is severely calcified and
unavailable to introduce balloon catheter or stent. To conduct atherectomy treatment methods,
accustoming professionals, order and get ready the treatment materials for necessity.
We successfully performed rotablation in severely calcified mLAD of 56 years of male patient by
staged PCI, whose infarct related artery Lcx was revascularized 3 months previously. As a result the
patient was fully revascularized, the balloon catheter passed through the narrowing and stent was
implanted successfully.
4.Study on structure and functions of organs involved in the formation of khuumii sound
Rentsendorj Ts ; Enebish S ; Juramt B ; Uurtuya Sh ; Shine-Od D ; Ganchimeg P ; Byambasuren L ; Dorjsuren Ts ; Erdembileg Ts ; Amgalanbaatar D ; Dagdanbazar B ; Nyamdorj D
Mongolian Medical Sciences 2020;192(2):3-9
Introduction:
Khuumii (throat singing) is a unique form of art derived from the nomadic population of Central Asia,
producing two or more “simultaneous” sounds and melodies through the organ of speech.
Material and Methods:
The aim of the study is to identify the anatomical structures involved in the formation of khuumii
and the features and patterns of their functions and compare each type of khuumii as performed by
Mongolian people. A total of 60 participants aged 18-60 years (54 men and 6 women) were selected
by non-random sampling method using cross-sectional study. Statistical analysis was performed
using SPSS 23 software using questionnaires, X-ray, endoscopy, sound research method, and
general blood tests.
Results:
90.7% of the khuumii singers were male and 9.3% were female. The average height of the participants
was 172.91±0.93 cm (arithmetic mean and mean error), average body weight was 77.53±2.46 kg,
and body mass index was 25.93±5.31 respectively. Heart rate was 92.19±20.71 per minute prior to
khuumii while 133.19±19.09 after performing khuumii and 85.81-98.56 at 95% confidence interval. In
terms of ethnicity (ethnographically), the Khalkh were the largest ethnic group (72.1%), followed by
Bayad, Buryatia, Darkhad, Torguud, and Oirat (2.3%), respectively. 60.5% of the participants were
professional khuumii singers who graduated from relevant universities and colleges. The process of
Khuumii was recorded by X-ray examination, and laryngeal endoscopy evaluated the movement of
true and false vocal chords, interstitial volume, movements of epiglottis and arytenoid cartilage, and
mucosa. Khuumii increases the workload of the cardiovascular system by 70-80%. Furthermore, the
sound frequency is 2-4 times higher than that of normal speech, and sound volume is 0.5-1 times
higher. 95.3% of throat singers did not have a sore throat, 88.4% did not experience heavy breathing,
and 74.1% had no hoarseness. During the formation of khuumii sound, thoracic cavity, diaphragm,
and lungs regulate the intensity of the air reaching the vocal folds, exert pressure on the airways and
vibrate the sound waves through air flows passing through the larynx and vocal folds. Mouth-nose
cavity as well as pharynx are responsible for echoing the sound.
Conclusion
It is appropriate to divide khuumii into two main types according to structural and functional changes
in the organs involved; shakhaa and kharkhiraa. Khuumii, the “Human music” originating from the
people of Altai Khangai basin by imitating the sounds of nature with their own voice in ancient times,
spread all over the world from Mongolia and it is proposed to classify khuumii into two main types of
shakhaa and kharkhiraa in terms of structural involvement and functionality.
5.RESULT OF 7-YEAR STUDY ON RESTENOSIS AND THROMBOSIS IN AFTER PCI TREATMENT SETTING
Lkhagvasuren Z ; Narantuya D ; Batmyagmar Kh ; Erdembileg D ; Bayaraa T ; Byambatsogt L ; Erdenechimeg M
Innovation 2018;12(4):6-9
BACKGROUND. The aim of this study was to investigate the prognostic impacts of drug-eluting stents (DES) and bare-metal stents (BMS) in patients undergoing percutaneous coronary intervention (PCI) and risk factors of stent restenosis.
MATERIAL AND METHODS. We conducted a retrospective cohort study based on the Angiographic diagnostic and treatment Department of 3rd State Central Hospital of Mongolia. Patients who had undergone coronary stenting between 2000 and 2017 were recruited and monitored until the end of 2010.
RESULTS. Among a total of 4520 selected patients with a mean age of 58±7 years, 2125 subjects had BMS and 2395 subjects had DES. The incidence of stent restenosis and stent thrombosis were significantly lower in the DES (37; 1,5%) group as compared with the BMS (201; 9,4%) group. Patients who have stent restenosis presented comorbidities, such as diabetes 214(47,8%), hypertension 54(22,6%), prior PCI 21(8,2%), re-infarction 12(5,04%), chronic kidney disease 16(6,7%), hyperlipidemia 21(8,2%).
СONCLUSION. Implantation of DES was related to better outcomes than for BMS, in terms of reducing restenosis and stent thrombosis after PCI. STEMI patients who have co morbidities have greater risk of stent stenosis and thrombosis
6.МОНГОЛ ЛИМБЭ ХӨГЖМӨӨР ХӨГЖИМДӨХӨД ОРОЛЦОХ ЭРХТНИЙ АНАТОМИ, ФИЗИОЛОГИЙН ЗАРИМ ҮЗҮҮЛЭЛТҮҮД
Dorjsuren Ts ; Amgalanbaatar D ; Erdembileg Ts
Innovation 2017;3(3):12-14
BACKGROUND: The limbe is a traditional Mongolian instrument that has been used since the ancient times, and the performer uses a unique method called circular breathing to play it. The circular breathing technique is significant heritage of the Mongolian people, and has been recognized by UNESCO World Heritage. Aim: To study the anatomy and physiology that take part in playing the Mongolian limbe with the circular breathing technique.
METHODS: We have studied 20 flutists using case control study method. The flutists’ change of gas compound in blood have been studied with a gas analyzer after playing for 10 minutes with the circular breathing. When the flutists play it with circular breathing, the anatomical structures and their function have been studied and documented by an endoscopy, X-ray and a 320 row area detector CT.
RESULTS: The 20 participants were between the ages of 22-56 with the circular breathing experience of 2 to 37 years. After playing the instrument for 10 minutes, we found the following results: 67.7% of the participants developed alkolosis, 23.5% hypocapnia, 5.9% hypercapnia, 94.1% hypoxia, and all participants’ oxygen saturation decreased. The lingual muscles, upper and under muscles of the hyoid bone, larynx and vocal cords are the main structures of the circular breathing.
CONCLUSION: Playing Mongolian limbe with the circular breathing leads to hypoxia, thus the circular breathing stops. It is important to note that this process does not depend on flutist’s age, their practice time, and their personal technique. However, we concluded that the time of performance without interruption depends on individual’s physiological characteristics. In order to study the issues of anatomy and physiology that take part in playing the Mongolian limbe with the circular breathing, we have studied 20 flutists using case control study method. The flutists’ change of gas compound in blood have been studied with a gas analyzer after playing 10 minutes by the circular breathing. When the flutists play it with circular breathing, the anatomical structures and their function have been studied and documented by an endoscopy and X-ray. The lingual muscles, upper and under muscles of the hyoid bone, larynx and vocal cords take part in the circular breathing by limbe as a main rule. Playing Mongolian limbe with the circular breathing lead to hypoxia thus the circular breathing stops. This process does not depend on flutist’s age, their practice time, and their private technique. But we concluded that how long time they play it without interruption depends on individual’s physiological singularity.
Result Analysis
Print
Save
E-mail