1.Mongolian translation and reliability assessment of the PedsQL™ gastrointestinal symptoms module standard form in pediatric patients with gastrointestinal disorders
Bulgantsetseg G ; Namuun G ; Enkhtuvshin N ; Enkhzul N ; Davaajav O ; Tserendavga D
Mongolian Journal of Health Sciences 2026;95(5):217-222
Background:
The Pediatric Quality of Life Inventory™ (PedsQL™) is a modular, multidimensional instrument designed to assess health-related quality of life (HRQoL) in children and adolescents aged 2 to 18 years. It encompasses both child self-report and parent proxy-report formats and includes generic as well as disease-specific modules, enabling comprehensive HRQoL assessment across healthy and clinical pediatric populations. In Mongolia, gastrointestinal (GI) disorders represent the second leading cause of morbidity among children aged 10 to 14 years. The assessment of HRQoL in children with GI disorders — particularly those with chronic conditions — is of considerable importance for clinicians and researchers in conducting epidemiological surveillance, monitoring treatment outcomes, and evaluating findings from clinical trials.
Aim:
To translate the Pediatric Quality of Life Inventory–Gastrointestinal Symptoms Module Standard Form (PedsQL™-GI version standard form) into Mongolian and to evaluate its internal consistency reliability.
Materials and Methods:
The PedsQL™-GI version standard form was selected for translation following written authorization from the original developers. The bilingual forward translation was conducted by a team comprising a professional linguist and a pediatrician with 15 years of clinical experience and academic proficiency in English, adhering to the developer-provided translation protocol. The preliminary Mongolian version was subsequently reviewed by a senior pediatrician with 25 years of professional experience and academic English, with particular attention to medical terminology accuracy and linguistic equivalence. A separate bilingual team — consisting of a second linguist and a pediatrician — then performed the backward translation into English. A small-group expert panel comprising the back-translation team and the research investigators convened to review discrepancies and finalize the English reconciled version, which was submitted to the original developers for approval before the official release of the Mongolian version. To evaluate the internal consistency reliability of the Mongolian version, the instrument was administered to 25 children aged 8–12 years and 25 adolescents aged 13 years and above, along with their respective caregivers. Data were analyzed using SPSS version 25.0, employing the Intraclass Correlation Coefficient (ICC) and Cronbach’s alpha coefficient.
Results:
The Cronbach’s alpha coefficient for the total instrument was α=0.96, indicating excellent internal consistency reliability. Test-retest reliability, assessed using the Intraclass Correlation Coefficient, yielded ICC=0.79, demonstrating satisfactory measurement stability over repeated administrations.
Conclusions
1. The overall semantic equivalence of the Mongolian version was 97.8%, and 96% of cognitive interview participants rated the questionnaire as “understandable” indicating that the clinical content and conceptual integrity of the original instrument were fully preserved throughout the translation process. 2. A total of 37 adaptation instances were identified during the translation process, encompassing six categories of linguistic and cross-cultural localization: age-appropriate modification, conversion of medical terminology into everyday language, linguistic and cultural adaptation, synonymous substitution, elaboration, and condensation. These adaptations collectively enhanced the content validity of the instrument. 3. The Mongolian version demonstrated excellent internal consistency reliability (Cronbach’s alpha α=0.96) and satisfactory test-retest reliability (Intraclass Correlation Coefficient ICC=0.79), both fully meeting international psychometric standards. These findings confirm that the instrument constitutes a reliable tool for assessing health-related quality of life in Mongolian children with chronic gastrointestinal disorders.
2.Evaluation of antioxidant activity and safety of onion (Allium cepa L.) peels
Anu G ; Tamir B ; Uranbileg B ; Altantogos M ; Oldokh O ; Enkhzul O
Mongolian Journal of Health Sciences 2026;95(5):141-145
Background:
Onion peel is a raw material rich in biologically active compounds; however, within the framework of food waste management in Mongolia, detailed studies and safety evaluations of this material remain insufficient. Therefore, it is necessary to scientifically determine the properties of onion peel waste generated from the food production sector and explore its potential for reuse.
Aim:
To evaluate the safety parameters of red and white onion (Allium cepa L.) peels generated during food processing and to determine their bioactive compound content and antioxidant activity.
Materials and Methods:
Red and white onion peels were used in this study. Safety parameters were determined using atomic absorption spectrometry (for heavy metals) and GC-MS/MS and LC-MS/MS (for pesticide residues). The raw materials were extracted with 70% ethanol, and dry extracts were obtained using a vacuum evaporator and freeze dryer. Total phenolic content (TPC) and total flavonoid content (TFC) were measured by spectrophotometric methods, while antioxidant activity was evaluated using the DPPH radical scavenging assay.
Results:
The analysis showed that the levels of lead, cadmium, and 205 pesticide residues in onion peels did not exceed the permissible limits, indicating that the material is safe. Phytochemical analysis revealed the presence of quercetin and luteolin derivatives in the dry extracts. The TPC (27.40±1.64%) and TFC (17.95±1.47%) of red onion peel extract were significantly higher than those of white onion peel extract (20.34±0.34% and 12.69±1.44%, respectively). The IC₅₀ values were 17.58 μg·mL⁻¹ for red onion and 19.41 μg·mL⁻¹ for white onion, indicating strong antioxidant activity for natural composite extracts.
Conclusion
Onion peel waste meets safety requirements and exhibits strong antioxidant activity. These findings demonstrate its potential as a valuable raw material for the development of antioxidant preparations and functional food additives aimed at preventing oxidative stress.
3. RESULT OF KASAI OPERATION, CHILDREN LIVER TRANSPLANTATION IN MONGOLIA
Chuluunkhuu D ; Zorigtbaatar M ; Nurjanar R ; Ganbayr L ; Otgonsuren G ; Dashaa M ; Enkhzul P ; Khandmaa B ; Sergelen O ; Bat-Ireedui B ; Ganzorig B ; Pagaldulam M ; Saruul G ; Tsendjav A
Journal of Surgery 2016;20(2):56-61
Introduction: Biliary Atresia is a fibroobliterativedisorder of the intra andextrahepatic bile ducts in infancy, which isgoing progressively cholestatic liver disease.The failed Kasaiportoenterostomy requiresliver transplantation. The goal of this studyis to show the outcome of Kasai operation,recent improvement and correlation the datato overseas.Methods and Materials: This study wasconducted in the department of generalsurgery of National Center for Maternal andChild Health of Mongolia between 2010 and2016 on a total of 66 infancies with biliaryatresia.Results: Patient diagnosed with biliaryatresia, which performed Kasai operationwithin first 2 months the outcome is verygood early and late post-operation period.There were 3 patients with 10 year survival, 4patients with 5-10 year and 28 patients with5 year survival after Kasai operation. The mostcomport age for liver transplantation is 1 yearlater after Kasai operation in Mongolia. Livertransplantation programme is necessary forMongolian pediatric surgery, and we thoughtour team was assembled.Conclusion: The children with biliary atresiaperform the Kasai operation within 2 monthsthe outcome is very good. Children with biliaryatresia often experience long wait times fortransplant unless exception points are grantedto reflect severity of disease.In Mongolia livertransplantation done in 2 child.
Result Analysis
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