Objective:To provide data support for optimizing aeromedical support to transporter flying personnel by comparing and analyzing the composition and variation of the medical grounding disease spectrum of them.Methods:The health profile data of transporter flying personnel who were grounded by the assessment in Air Force Medical Center from January 1, 2003, to December 31, 2020 were collected. They were grouped by grounded year (2003—2008, 2009—2014 and 2015—2020) and by post (pilot and air combat personnel). The age at the time of grounding, flying hours and grounding disease spectrum were statistically analyzed.Results:A total of 186 transporter flying personnel were enrolled, including 135 pilots (72.58%) and 51 air combat personnel (27.42%). The median grounding age of pilots was 34.0 (31.5, 39.0) years old, and the median grounding age of air combat crew was 43.0 (41.0, 46.0) years old. The top 4 system diseases in all flight grounding personnel were neurological diseases (21.51%), mental and psychiatric disorders (16.67%), cardiovascular system diseases (13.98%) and motion system diseases (10.75%). The difference in the component ratio of grounding diseases between the pilots and air combat personnel was significant ( P=0.039), and the grounding ratio of digestive system diseases in pilots was lower than that of air combat personnel ( χ2=5.40, P=0.020). The grounding ratio of motion system diseases in 2009—2014 group was lower than that of 2003—2009 group ( χ2=6.70, P=0.010). The grounding ratios of mental and psychiatric disorders in 2009—2014 and 2015—2020 group were higher than those of 2003—2008 group, with significant differences ( χ2=8.80, 7.33, P=0.005, 0.007). There were 76 types of diseases that caused transporter flying personnel grounding, and the top 3 diseases were hypertension, vascular headaches and lumbar disc herniation. Conclusions:The neurological diseases, mental and psychiatric disorders, cardiovascular system diseases and motion system diseases contribute most to the grounding of transporter flying personnel while the neurological diseases and mental and psychiatric disorders have resulted more and more groundings. As the higher flying training strength and time endurance required, the further disease spectrum analysis, as well as the corresponding prevention and treatment should be strengthened.

Objective:To provide data support for optimizing aeromedical support to transporter flying personnel by comparing and analyzing the composition and variation of the medical grounding disease spectrum of them.Methods:The health profile data of transporter flying personnel who were grounded by the assessment in Air Force Medical Center from January 1, 2003, to December 31, 2020 were collected. They were grouped by grounded year (2003—2008, 2009—2014 and 2015—2020) and by post (pilot and air combat personnel). The age at the time of grounding, flying hours and grounding disease spectrum were statistically analyzed.Results:A total of 186 transporter flying personnel were enrolled, including 135 pilots (72.58%) and 51 air combat personnel (27.42%). The median grounding age of pilots was 34.0 (31.5, 39.0) years old, and the median grounding age of air combat crew was 43.0 (41.0, 46.0) years old. The top 4 system diseases in all flight grounding personnel were neurological diseases (21.51%), mental and psychiatric disorders (16.67%), cardiovascular system diseases (13.98%) and motion system diseases (10.75%). The difference in the component ratio of grounding diseases between the pilots and air combat personnel was significant ( P=0.039), and the grounding ratio of digestive system diseases in pilots was lower than that of air combat personnel ( χ2=5.40, P=0.020). The grounding ratio of motion system diseases in 2009—2014 group was lower than that of 2003—2009 group ( χ2=6.70, P=0.010). The grounding ratios of mental and psychiatric disorders in 2009—2014 and 2015—2020 group were higher than those of 2003—2008 group, with significant differences ( χ2=8.80, 7.33, P=0.005, 0.007). There were 76 types of diseases that caused transporter flying personnel grounding, and the top 3 diseases were hypertension, vascular headaches and lumbar disc herniation. Conclusions:The neurological diseases, mental and psychiatric disorders, cardiovascular system diseases and motion system diseases contribute most to the grounding of transporter flying personnel while the neurological diseases and mental and psychiatric disorders have resulted more and more groundings. As the higher flying training strength and time endurance required, the further disease spectrum analysis, as well as the corresponding prevention and treatment should be strengthened.

This paper aimed to review the recent literature on the TCM treatment for stroke sequelae. The content summarized and discussed the definition of stroke sequelae, herbalmedicine, TCM patents, acupuncture and so on. Sequelae of stroke’s pathogenesis was mainly caused by deficiency generating stasis, so the treatment principles were to tonifying Qi and blood and promote circulation and remove stasis with the common prescriptions, such asBuyang-Huanwudecoction,Xuefu-Zhuyu decoction andDihuang-Yinzi. Meanwhile, Chinese medicine patents and acupuncture treatment canimprove the brain function and ADL.

Objective To investigate the role and value of the biliary stent in the treatment of large common bile duct stones. Methods Thirty-two patients with large common bile duct stones were underwent plastic biliary stenting after endoscopic stone extraction with oddi sphincterotomy, and were followed up for 6 months. Results Thirty-two patients were successfully placed biliary stents. The postoperative jaundice, abdominal pain and other symptoms were alleviated. The secondary endoscopic retragrade cholang iopancreatography (ERCP) was performed six months after surgery. Large stones disappeared in 3 cases, 25 cases were reduced to varying degrees, 4 cases showed no obvious narrowing in 32 patients with biliary stones. Twenty-nine patients with residual stones were taken stone again. The operation was successful in 25 cases . Four cases continued to be observed the drainage of biliary since the difficulties for taking stone. The success rate of treatment of large common bile duct stones by biliary stent was 87.5%. Conclusion The therapy of large common bile duct stones by biliary stent is of simple, short operation time, fewer complications, satisfactory results, safe and effective advantages.

AIM: To study on antisense oligoncleotides as inhibitor of human acute promyelocytic leukemia (HL-60) proliferation and C-myc protein expression. 　METHODS: Oligonucleotides with different lengths (18-21 mer) complementary to the definite regions of C-myc mRNA, modified groups (with S replaced O in internucleotide phosphate linkage) and unmodified ones (with natural internucleotide phosphate linkage) were designed and synthesized. These olignucleotides were tested for their activity on HL-60 cell and also for their toxicity on normal lymphatic cells of human. 　RESULTS: It was found that two of the oligonucleotides complementary to 5′-44-61 and 5′-556-576 the regions of C-myc mRNA exhibited great inhibitory effects (59.5 % and 62.7 %) on growth of HL-60 cells for a definite time. And no toxicity of the two antisense oligonucleotides was found on normal lymphatic cells of human. 　CONCLUSION: The sequence of antisense oligonucleotides complementary to 5′-44-61 of C-myc mRNA was designed newly by us may be turned into inhibitory medicine of HL-60 cells.