Objective To understand the current situation of the use of psychotropic drug off-label prescribing for nonorganic sleep disorder patients,and to provide evidence for the development of the expert consensus on off-label prescribing of psychoactive drugs in psychiatry.Methods Patients discharged in 2017 with nonorganic sleep disorders were enrolled in the study.The off-labelled prescribing of psychoactive drugs questionnaire was used to investigate the records retrospectively.The off-label prescribing situation was confirmed by the drug label in China.Results A total of 294 patients were enrolled.The total rate of off-labelled prescription was 70.1％ (206/294),the rate of off-labelled indication was 68.4％ (201/294),the rate of off-labelled population was 14.3％(41/294),and the rate of off-labelled dose was 5.4％ (16/294).Conclusion Off-label usage of psychotropic drugs is common and to standarize off-label prescribing with close supervision should be considered.

Objective To understand the current situation of the use of psychotropic drug off-label prescribing for nonorganic sleep disorder patients,and to provide evidence for the development of the expert consensus on off-label prescribing of psychoactive drugs in psychiatry.Methods Patients discharged in 2017 with nonorganic sleep disorders were enrolled in the study.The off-labelled prescribing of psychoactive drugs questionnaire was used to investigate the records retrospectively.The off-label prescribing situation was confirmed by the drug label in China.Results A total of 294 patients were enrolled.The total rate of off-labelled prescription was 70.1％ (206/294),the rate of off-labelled indication was 68.4％ (201/294),the rate of off-labelled population was 14.3％(41/294),and the rate of off-labelled dose was 5.4％ (16/294).Conclusion Off-label usage of psychotropic drugs is common and to standarize off-label prescribing with close supervision should be considered.

OBJECTIVE:To discuss the ways to improve the drug control outcome in China and to facilitate the related system reform.METHODS:The causes and countermeasures for the failure of drug control policy in China were analyzed comparatively using economic theory.RESULTS & CONCLUSIONS:Information dissymmetry in the medicine area,monopoly of medical institution and their evasion of control etc all resulted in the failure of price control policy.To avoid this failure,it is necessary to take reform measures in many aspects,enhance the scientificity of price control,and improve the conduction mechanism of price control policy.