Objective:To investigate the clinical characteristics, diagnosis and treatment strategy of umbilical endometriosis.Methods:The clinical data of 4 cases with umbilical endometriosis were analyzed and the related literatures were reviewed.Results:Ectopic umbilical endarterectomy was performed in 4 patients. Histopathology showed that there were endometrial glands, stroma and macrophages containing hemosiderin in subdermal fibrous tissue, which was confirmed asumbilical endometriosis.Conclusion:The incidence rate of umbilical endometriosis is low, but there is a possibility of recurrence and malignant transformation. Gynecological examination should be emphasized in clinic. Early detection and early treatment should be paid attention to, and combined with pathological biopsy, diagnosis should be made to reduce missed diagnosis and improve the cure rate.

Objective:To investigate the clinical characteristics, diagnosis and treatment strategy of umbilical endometriosis.Methods:The clinical data of 4 cases with umbilical endometriosis were analyzed and the related literatures were reviewed.Results:Ectopic umbilical endarterectomy was performed in 4 patients. Histopathology showed that there were endometrial glands, stroma and macrophages containing hemosiderin in subdermal fibrous tissue, which was confirmed asumbilical endometriosis.Conclusion:The incidence rate of umbilical endometriosis is low, but there is a possibility of recurrence and malignant transformation. Gynecological examination should be emphasized in clinic. Early detection and early treatment should be paid attention to, and combined with pathological biopsy, diagnosis should be made to reduce missed diagnosis and improve the cure rate.

Objective To investigate the epidemiology characteristics of crawfish related rhabdomyolysis (RM) in Nanjing, 2016.Methods Outpatient and inpatient electronic medical system of 21 hospitals in Nanjing during 2016 were retrospectively searched, and all the patients diagnosed with RM were selected. The patients with none crayfish-related RM was excluded. The epidemiology characteristics were depicted. The geographic information system (GIS) was used to collect, manage and analyze the spatial data, to visualize it, to analyze the spatial distribution features of the disease, and to explore the cause of disease prediction. GeoDa 1.8 software was used to analyze the global and local spatial auto-correlation.Results A total of 1183 patients with crawfish related RM were initially screened, excluding 59 patients with RM caused by trauma, severe exercise, heat stroke, myositis, poisoning, drugs, and genetic diseases, and 1124 patients were enrolled. The proportion of men was 36.48% (410/1124) with an incidence of 12.54/100 thousands; while of women was 63.52% (714/1124) with an incidence of 21.86/100 thousands. The median age at onset was 34 (28, 43) years. From July to August, the incidence of crawfish related RM was the highest, accounting for 96.53% of the total number of cases. The top four incidence areas were Pukou (41.54/100 thousands), Jianye (25.94/100 thousands), Qixia (25.73/100 thousands), Gulou (25.04/100 thousands), all of which were adjacent to the Yangtze River. Global spatial autocorrelation analysis showed: MoranI = 0.427,Z = 2.646,P = 0.003, suggesting that the crawfish related RM had positive spatial autocorrelation. The results showed that the spatial structure of crawfish related RM existed in Nanjing in 2016. Local spatial autocorrelation analysis showed that the high-high concentration areas were Pukou, Jianye and Liuhe. The incidences of above three areas which were the Nanjing section of the lower reaches of the Yangtze River flowed through the region and surrounding areas were higher than the overall incidence of Nanjing.Conclusion The prevalence of crawfish related RM in Nanjing during 2016 had an obvious region-concentrated character and global spatial autocorrelation with the high prevalent regions mainly concentrated in the urban areas adjacent to the Yangtze River.