Objective:This study aims to examine the incidence and risk factors of violent behaviors in community-dwelling unmedicated patients with severe mental disorders in Shenzhen.Methods:The baseline and follow-up data of unmedicated patients with severe mental disorders were collected from the Information Management System of Mental Health Prevention and Control in Shenzhen. The incidence of violent behaviors in unmedicated patients was described. The influencing factors of violent behaviors were analyzed using logistic regression model.Results:A total of 3 163 patients were included. The incidence of violent behaviors was 9.1% (288/3 163) in 2019. Multivariate logistic regression analysis showed that having an acute illness onset ( OR=1.589, 95 %CI 1.181-2.139) was the risk factor of violent behaviors, while having cohabitants ( OR=0.596, 95 %CI 0.410-0.867), being diagnosed as mental retardation comorbid with psychotic disorders ( OR=0.432, 95 %CI 0.199-0.938), having application for carers allowances ( OR=0.440, 95 %CI 0.319-0.606), and participating in family doctor services ( OR=0.642, 95 %CI 0.492-0.838) and community face-to-face interviews during 2019 ( OR (1-2 times vs. 0 times)=0.633, 95 %CI 0.466-0.861; OR (3-4 times vs. 0 times)=0.546, 95 %CI 0.368-0.811) were the protective factors. Conclusions:The incidence of violent behaviors is high in unmedicated patients with severe mental disorders with acute illness onset. The improvement of comprehensive level of community mental health services and the development of targeted intervention measures would help to reduce the occurrence of violent behaviors among unmedicated patients with severe mental disorders in the community.

Objective:This study aims to examine the incidence and risk factors of violent behaviors in community-dwelling unmedicated patients with severe mental disorders in Shenzhen.Methods:The baseline and follow-up data of unmedicated patients with severe mental disorders were collected from the Information Management System of Mental Health Prevention and Control in Shenzhen. The incidence of violent behaviors in unmedicated patients was described. The influencing factors of violent behaviors were analyzed using logistic regression model.Results:A total of 3 163 patients were included. The incidence of violent behaviors was 9.1% (288/3 163) in 2019. Multivariate logistic regression analysis showed that having an acute illness onset ( OR=1.589, 95 %CI 1.181-2.139) was the risk factor of violent behaviors, while having cohabitants ( OR=0.596, 95 %CI 0.410-0.867), being diagnosed as mental retardation comorbid with psychotic disorders ( OR=0.432, 95 %CI 0.199-0.938), having application for carers allowances ( OR=0.440, 95 %CI 0.319-0.606), and participating in family doctor services ( OR=0.642, 95 %CI 0.492-0.838) and community face-to-face interviews during 2019 ( OR (1-2 times vs. 0 times)=0.633, 95 %CI 0.466-0.861; OR (3-4 times vs. 0 times)=0.546, 95 %CI 0.368-0.811) were the protective factors. Conclusions:The incidence of violent behaviors is high in unmedicated patients with severe mental disorders with acute illness onset. The improvement of comprehensive level of community mental health services and the development of targeted intervention measures would help to reduce the occurrence of violent behaviors among unmedicated patients with severe mental disorders in the community.

Objective: To investigate personality disorders of recidivists. Method: PDQ (Personality Diagnostic Questionnaire) was administered to 122 recidivist and 932 first offenders. Result: Compared with first offenders, the recidivists had higher possibility to be a drug abuser or to have traffic in narcotics, they had lower education level and got higher scores in total score, paranoid, antisocial, borderline subscales of PDQ. Conclusion: The recidivists have more personality defects.

Objective　To study the functional condition of α2-adrenergic receptors in patients with major depression. Methods　Sleep EEG of 15 depressed patients diagnosed according to CCMD-2-R was compared with that of 15 normal controls. Clonidine hydrochloride was administered intravenously within 10 minute after the first rapid eyemovement (REM) sleep period. Results　The percent of REM in depressive patients was higher than in controls at baseline. There was no significant differences between the two groups in NREM after clonidine administration, but the percent of REM, frequency of REM and time of REM decreased in the two groups. The interval between the first and the second REM period (REM1-REM2) decreased more in patients with depression than in controls(P<0.01). It was suggested clonidine had little influence on the NREM sleep, but significantly effected on the REM lantency, total REM period, and interval between REM1 and REM2, and REM sleep response to clonidine bluntly in depression. Conclusion　It indicates there may be deficiency of α2-adrenergic receptors in major depression.

Objective　To study the functional condition of α2-adrenergic receptors in patients with major depression. Methods　Sleep EEG of 15 depressed patients diagnosed according to CCMD-2-R was compared with that of 15 normal controls. Clonidine hydrochloride was administered intravenously within 10 minute after the first rapid eyemovement (REM) sleep period. Results　The percent of REM in depressive patients was higher than in controls at baseline. There was no significant differences between the two groups in NREM after clonidine administration, but the percent of REM, frequency of REM and time of REM decreased in the two groups. The interval between the first and the second REM period (REM1-REM2) decreased more in patients with depression than in controls(P<0.01). It was suggested clonidine had little influence on the NREM sleep, but significantly effected on the REM lantency, total REM period, and interval between REM1 and REM2, and REM sleep response to clonidine bluntly in depression. Conclusion　It indicates there may be deficiency of α2-adrenergic receptors in major depression.

Objective: To evaluate the defense mechanisms most frequently used by Chinese patients with panic disorder.Methods: Forty-seven panic patients with or without agoraphobia,and thirty-senven controls participated in the study.The Hamilton Depression Scale(HAMD,Hamilton Anxiety Scale(HAMA) and global assessment function(GAF) were applied to assess the severity of depression and anxiety symptoms and social and occupational function,respectively.Defensive Style Questionnaire(DSQ-88) was used to evaluate defense mechanisms.Results: Compared with controls,panic patients had higher scores in projection,splitting,regression,somatization and total scores of immature defenses and higher scores in idealization,pseudo-altruism,omnipotence-devaluation,attiliation and total scores of neurotic defenses(P