Objective:To analyze the electroencephalogram(EEG) average relative power spectrum in patients with unipolar and bipolar depression under the eyes-open and eyes-closed resting states.Methods:A total of 38 patients with unipolar depression (UD group), 48 patients with bipolar depression (BD group), and 43 healthy controls (HC group) were recruited from August 2022 to December 2023.The 64-channel EEG was recorded under eyes-open (EO) and eyes-closed (EC) resting states which alternated twice. The Mann-Whitney U test and Kruskal-Wallis H test were performed by SPSS 25.0 software. Results:There were no significant differences in the average relative power of delta and beta bands among the UD, BD and HC groups in all EO and EC states (all P>0.05). The average relative power of theta band in the three groups showed statistically significant differences in all EO and EC states ( H=7.852-12.583, all P<0.05). Further pairwise comparisons showed that in the first EO and EC stage, the average relative power of theta band of the UD and BD groups were significantly higher than that of the HC group (EO1: 0.18(0.17, 0.21), 0.19(0.16, 0.21), 0.16(0.14, 0.18), EC1: 0.15(0.13, 0.21), 0.15(0.13, 0.20), 0.13(0.10, 0.16); all P<0.05).In the second EO and EC stage, the average relative power of theta band of the BD group was significantly higher than that of the HC group (EO2: 0.18(0.15, 0.22), 0.16(0.14, 0.18), EC2: 0.15(0.13, 0.19), 0.13(0.11, 0.16); both P<0.05).There were statistically significant differences in the average relative power of alpha band among the three groups in the first EO and EC stage, as well as the second EC stage ( H=5.027-10.668, all P<0.05). Further pairwise comparisons showed that in the first EO stage, the average relative power of alpha band in the BD group was significantly higher than that in the UD group (0.20(0.16, 0.25), 0.14(0.11, 0.22), P=0.003), and in the following EC stages, the average relative power of alpha band in the UD group was significantly lower than that in the HC group (EC1: 0.40(0.33, 0.46), 0.51(0.40, 0.58), EC2: 0.41(0.35, 0.50), 0.48(0.43, 0.58); both P<0.05). Conclusion:At the initial stage of the resting state, both unipolar and bipolar depression patients demonstrate abnormal theta band activity under the eyes-open and eyes-closed states, while the alpha band activity under the eyes-open condition differs between the two groups of patients. These findings may provide potentially objective biomarkers to assist the diagnosis of unipolar and bipolar depression patients in clinical settings.

Objective:To analyze the electroencephalogram(EEG) average relative power spectrum in patients with unipolar and bipolar depression under the eyes-open and eyes-closed resting states.Methods:A total of 38 patients with unipolar depression (UD group), 48 patients with bipolar depression (BD group), and 43 healthy controls (HC group) were recruited from August 2022 to December 2023.The 64-channel EEG was recorded under eyes-open (EO) and eyes-closed (EC) resting states which alternated twice. The Mann-Whitney U test and Kruskal-Wallis H test were performed by SPSS 25.0 software. Results:There were no significant differences in the average relative power of delta and beta bands among the UD, BD and HC groups in all EO and EC states (all P>0.05). The average relative power of theta band in the three groups showed statistically significant differences in all EO and EC states ( H=7.852-12.583, all P<0.05). Further pairwise comparisons showed that in the first EO and EC stage, the average relative power of theta band of the UD and BD groups were significantly higher than that of the HC group (EO1: 0.18(0.17, 0.21), 0.19(0.16, 0.21), 0.16(0.14, 0.18), EC1: 0.15(0.13, 0.21), 0.15(0.13, 0.20), 0.13(0.10, 0.16); all P<0.05).In the second EO and EC stage, the average relative power of theta band of the BD group was significantly higher than that of the HC group (EO2: 0.18(0.15, 0.22), 0.16(0.14, 0.18), EC2: 0.15(0.13, 0.19), 0.13(0.11, 0.16); both P<0.05).There were statistically significant differences in the average relative power of alpha band among the three groups in the first EO and EC stage, as well as the second EC stage ( H=5.027-10.668, all P<0.05). Further pairwise comparisons showed that in the first EO stage, the average relative power of alpha band in the BD group was significantly higher than that in the UD group (0.20(0.16, 0.25), 0.14(0.11, 0.22), P=0.003), and in the following EC stages, the average relative power of alpha band in the UD group was significantly lower than that in the HC group (EC1: 0.40(0.33, 0.46), 0.51(0.40, 0.58), EC2: 0.41(0.35, 0.50), 0.48(0.43, 0.58); both P<0.05). Conclusion:At the initial stage of the resting state, both unipolar and bipolar depression patients demonstrate abnormal theta band activity under the eyes-open and eyes-closed states, while the alpha band activity under the eyes-open condition differs between the two groups of patients. These findings may provide potentially objective biomarkers to assist the diagnosis of unipolar and bipolar depression patients in clinical settings.

Objective:To retrieve, evaluate and summarize the best evidence for volume management in patients with chronic heart failure.Methods:Domestic and foreign databases and relevant society websites were systematically reviewed for guidelines, expert consensus, systematic reviews, evidence summaries and recommended practices related to volume management in patients with chronic heart failure. The retrieval time limit was from the establishment of the database to August 31, 2021. The literature was screened according to the inclusion and exclusion criteria of the literature, and the evidence was extracted after the quality evaluation of the literature.Results:A total of 20 articles were included, including 8 guidelines, 3 expert consensus, 5 systematic evaluation, 2 evidence summary and 2 recommended practices. A total of 37 pieces of evidence were summarized from 6 aspects, including evaluation and monitoring, diuretic use, fluid intake management, sodium intake management, volume load aggravation management and health education.Conclusions:Medical staff should formulate a volume management plan that is in line with Chinese chronic heart failure patients based on the best evidence based on the actual clinical characteristics, so as to slow down the disease progression of patients with chronic heart failure and reduce the admission rate of patients.

Objective To explore clinical manifestations, image findings, histopathological characteristics and surgical treatment for glomus tumor. Methods Clinical data of 18 patients with glomus tumor, who underwent surgical treatment from 1992 to 2002 was analysed retrospectively. Results There were 11 males and 7 females. The mean age was (39?7) years old, with 11.1% (2/18) cases of multiple tumors. Glomus tumor was located in the subungual region or extremities of limbs in 61.1% (11/18) cases, the diameter of the tumor was less than 10 mm in 88.9% (16/18) cases. The clinical misdiagnosis rate was as high as 61.1% (13/18).B ultrasound made correct diagnosis in 85.7% (6/7) cases with tumor location other than in the subungual region or extremities of limbs, while radiological finding rate was only 33.3% (4/12).There were 16 glomus tumors histopathologically classified as the glomangiomatous type, and 2 the solid type. The immunochemistry in 10 cases were all positive for Vementin. Conclusions Glomus tumor in the subungual region or extremities of limbs could be diagnosed without difficulty, while it was usually difficult to make correct diagnosis in cases with tumor at the other site for lack of specific symptoms and physical signs. Surgical removal should be the golden standard for the treatment of this tumor.