Background: Regularly participate international High-level in sports athletes national and competitions and engage in intense training, developing endurance and resilience. Measuring blood lactate levels is crucial for improving an athlete’s performance, assessing sports performance, and enhancing the effectiveness of future training. Aim: To study the relationship between lactate levels in the blood plasma and lactate dehydrogenase enzyme activity in Mongolian National Team athletes. Materials and Methods: The study involved 51 athletes from the Mongolian National Team. Anaerobic capacity was assessed using a Monark 894E Ergomedic Peak Bike, designed to apply exercise load. Blood serum lactate level and lactate dehydrogenase enzyme activity were determined using a Biobase BK-280 fully automated biochemical analyzer. Heart rate, peripheral blood oxygen levels, and oxygen saturation were measured using a pulse oximeter. Results: The average age of the participants was 24.04 ± 4.15 years, with an average height of 168 ± 8.78 cm and an average weight of 71.01 ± 7.69 kg. The average BMI was 24.82 ± 4.12 kg/m². Pre exercise lactate levels averaged 3.84 ± 0.75 mmol/L, while post-exercise lactate levels averaged 9.67±3.52 mmol/L. The average heart rate before exercise was 66.04±8.9 bpm, while post-exercise heart rate was 123.6±16.06 bpm. The average VO₂ max was 95.18±2.48. Conclusion The lactate levels before and after exercise among the athletes participating in the study showed significant differences in the age groups 20-29 (p<0.0001). When comparing lactate levels before and after exercise by sport, statistically significant increases were observed in freestyle wrestling and judo athletes (p<0.0001)

Introduction: The last decade has seen a dramatic increase in general interest in and research into vitamin D, with many athletes now taking vitamin D supplements as part of their everyday dietary regimen. The most recognized role of vitamin D is its regulation of calcium homeostasis; there is a strong relationship between vitamin D and bone health in non-athletic individuals. Vitamin D is responsible for regulation of calcium and phosphate metabolism and maintaining a healthy mineralized skeleton. It is also known as an immunomodulatory hormone. Experimental studies have shown that 1,25-dihydroxyvitamin D, the active form of vitamin D, exerts immunologic activities on multiple components of the innate and adaptive immune system as well as endothelial membrane stability. Studying the level of vitamin D in athletes in relation to age group, body mass index, and type of sport is important for reducing the risk of injury and infection in athletes and improving performance and success in sports. Goal: To determine the 25-hydroxyvitamin D [25(OH)D] levels in the plasma of the trained athletes and their vitamin D status to compare of their sports type. Materials and Methods:
Sample size
Using a cross-sectional design, a total of 71 athletes aged 20-43 from the sports medicine research center and the national team was selected by sampling.
Method of the Laboratory analyses
The body mass index and blood plasma level of 25 hydroxy vitamin D of the athletes participating in the study were compared by sports type and analyzed using descriptive statistics. Comparison of survey data was performed using Pearson’s correlation method. Results: In the study, 71 athletes of the Mongolian national team participated in 5 types of sports. Descriptive analysis was performed on the general parameters of the athletes, body mass index, type of sport, level of vitamin D in the blood, etc.
An avarege level of vitamin D of the athletes who participated in our study were 22.27±12.9 ng/ml, in the age group of 20-29 years, and compared to the body mass index, it was the highest level in the athletes of normal weight. Conclusions
1. The level of vitamin D of the athletes who participated in our study was the highest in the age group of 20-29 years, 22.27±12.9 ng/ml, and compared to the body mass index, it was the highest level in the athletes of normal weight.
When studying the level of vitamin D of the participants in comparison with the type of sport, the freestyle wrestlers had a higher level of 34.75±15.13 ng/ml, while the judo wrestlers had a lower level of 12.69±5.17 ng/ml.

The prevalence and type of congenital cleft of the lip and palate in mongolia, affiliation of the patients Background: The prevalence of congenital cleft lip and palate is different internationally. There are some research papers which identifying the rate of this abnormality in Mongolia, the latest one shown the result that one cleft case for 1072 live births (Ayanga GN et all, 2012). Aim: to determine/update the prevalence and types of congenital cleft lip and palate in Mongolia Materials and methods: we include the data from all cleft patients who were born between 01 of January, 2011-31 of December, 2021 to this survey retrospectively. We used the e-history for cleft patients, which developed by the department of Maxillofacial surgery since 2011. Results: Totally 1308 cleft patients included to our survey. The prevalence is one cleft cases for 652 live births in Mongolia, and 34,1% is cleft of the lip, 41,4% is cleft of the lip and palate, and 24,5% is cleft palate only of all cases. Also the rate was differently among provinces, as one for 429 live births in Khuvsgul province, and one for 1223 live births in Uvs province. Conclusions: the prevalence of cleft lip and palate in Mongolia 1000:1.5 or one for 652 live births. The highest rate established in Khuvsgul province, and the lowest in Uvs province.

Background: Diabetes mellitus (DM) is a chronic progressive metabolic disorder. According to International Diabetes Foundation (IDF) estimation in 2019, globally 463 million adults have diabetes among the population aged 20-79. If this trend continues, 700 million of people will have diabetes by 2045, and the larger increases will occur in low- and middle-income countries. In Mongolia, the prevalence of Diabetes 5.4%. Regularly assessing the quality of life (QOL) in the control of patients with diabetes is important to evaluate the effectiveness of management, to plan treatment and thus to improve monitoring. Meaningful. The purpose of our study was to evaluate the Validity and Reliability of the Mongolian Version of the World Health Organization’s Quality of Life Questionnaire (WHOQOLBREF) in patients with Type 2 Diabetes. Methods: The cross sectional survey was conducted in Ulaanbaatar. For the study 150 patients with T2DM were recruited, who have met the inclusion criteria and agreed to the informed consent. In the study, self-management control, beliefs about illness, depression were assessed. Additionally, anthropometric measurements, blood pressure (BP), levels of glucated hemoglobin level (HbA1C), lipids and fasting blood glucose (FBG) at the baseline and after 3 months follow ups were measured. Statistical analyses was performed using SPSS 21 software. Results: The study involved newly diagnosed Type 2 diabetes with mean age of 49,4±8,9 years. 65 men (43,6%), 85 women (56,7%) and 39,3% of the participants had a family history of diabetes. The Cronbach’s alpha for analysis of the reliability of the WHOQOLBREF was a=0.74-0.84. The patient’s fasting blood glucose FBG, HbA1c, and low-density lipoproteins (LDL) were statistically significantly higher (p <0.05) than normal and the triglyceride (TG) was increased, but it was not statistically significant (p> 0.05). The mean TG had statistically significant (p <0.05) increase by sex. There is a need for further study of the specific questionnaire of QOL people with diabetes. Conclusion The Mongolian version of the WHO Quality of Life Questionnaire evaluating diabetes patients, the internal consistency of the questionnaire was reliable and the validity was a = 0.74-0.84.

ABSTRACT. Recurrent aphthous stomatitis, or RAS, is common oral disorder of uncertain etiopathogenesis for which only symptomatic therapy is available. This article reviews the current clinical features of RAS among study patients and the result of therapeutic effects of the herbal preparation Akhizunber. Over the past four years we have treated 61 RAS patients with different clinical forms by herbal preparation Akhizunber or Alumekatin. The distribution of clinical forms RAS RAS among study patients were minor aphthae -75.4%, major aphthae -16.4% and herpetiform ulcers -8.2% respectively. The healing time of treated Akhizunber was in minor aphthae -9.28±4.82 days, major aphthae -14 days and herpetiform ulcers -12 days. Of the total study participants, the patients treated by Akhizunber reported a rapid and complete recovery from RAS during treatment compared with treated patients by Alumekatin. Treatment with herbal preparation Akhizunber can be effective for patients suffering from RAS in any clinic form, regardless of their ulcer number and size.

BACKGROUND. Congenital Cleft Lip and/or Palate (CL/P) is a common craniofacial birth defect and occurs 1 per 500-700 live births in average. Children with CL/P at a higher risk for speech/language problems due to the anatomical and structural differences in the oral and nasal cavities, Velopharyngeal Insufficiency causing speech disorders with articulation, phonation, and resonance, respectively. It leads to long-lasting adverse outcomes, influencing quality of life and causes obstacles in child’s socialization. Speech in 2007 Therapy team of School of Dentistry ( G. Ariuntuul , B. Bulgan, U. Azzaya, B. Batsukh, M. Bat-Erdene), Mongolian National University of Medical Sciences (MNUMS) (former Health Sciences University of Mongolia) established and successfully conducted a first clinical speech therapy sessions for children with clefts in Mongolia based on the Department of Oral and Maxillofacial Surgery (G. Ayanga et al.) of National Maternal and Children’s Health Center (NMCHC). Since 2012 the speech therapy team of School of Dentistry, officially transferred the equipped operating speech room to NMCHC and speech pathologist B. Bulgan, supervised and trained by Ariuntuul G. recruited by NMCHC for a full time position and working as a member of multidisciplinary team till present. OBJECTIVES. To assess and analyze registry data of children with clefts, visited speech therapy sessions of speech pathology team of School of Dentistry, MNUMS during 2007 through 2012. MATERIAL AND METHODS. Registry based retrospective study was conducted to obtain demographic and speech disorder related data of children with clefts, visited speech therapy sessions between 2012-2017 at the NMCHC. RESULTS. In total 203 participants are attended the speech therapy sessions: 103 male (51%), 100 female (49%). Out of total 203 children 144 (71%) had Cleft Lip and Palate (CLP), 44 had cleft palate only (22%), 15 had cleft lip (7%), respectively. Average age for primary cleft surgery was 1y13m, where as for secondary was 4y22m. CONCLUSION. For speech therapy session for children with clefts boys were dominant compared to girls (1:1.03). By the types of clefts children diagnosed with Cleft Lip and Palate was prevalent to attend treatment classes. There is a need in early CL/P diagnosis, using birth screening and furthermore, traning of speech therapists/pathologists are important for development of multidisciplinary team, surgery outcome and improvement of quality of life of children with clefts.

Background: Poor laboratory quality can lead to misdiagnosis and inappropriate treatment of patients. To demonstrate the quality and reliability of their services, medical laboratories seek accreditation to ISO 15189. We have initiated a project to assist laboratories in their efforts to obtain the accreditation. Goal: Conduct a gap analysis of the status of preparedness of medical laboratories for accreditation. Materials and Methods: Six laboratories are selected for participation in the project. In the first phase of the project, a gap analysis of the participant laboratories is conducted using an Excel program based on ISO 15189 requirements. Results: The findings reveal that the participant laboratories are the strongest in Organization and management of laboratory, Quality of examination results, Personnel and facility management and in Laboratory information management. The majority of the laboratories are hospital based, and their organization and management are well established and functional mostly due to centralized administrative guidance. The concept of quality control is effectively adapted in medical laboratories, therefore ensuring the quality of examinations and the data management are usually in line with the requirements. Weaker areas include Evaluation and audits, and Document control. Even though the laboratories do conduct evaluations and control, they do not do it regularly and, most importantly, do not keep records routinely, which cause the higher gap rate. Conclusion Policies to meet ISO 15189 requirements are in place in the participant laboratories, but their documentation and records keeping are insufficient.

BACKGROUND The occurrence of facial injuries tends to be high compared to injuries in other parts of the body, because the face is without a protective covering, and the chin mandible is the most prominent bone in this region of the body. According to several studies, mandibular fractures account for 59% of all facial fractures. Mandibular fractures usually occur in 2 or more locations because of the bone’s U shape. This article aims to analyze retrospectively the age, gender, etiology, and anatomic distribution of mandibular fractures. METHODS The data for this study were obtained from the medical records of 1217 cases treated at Department of Oral and Maxillacial Surgery at National First Central Hospital of Mongolia in 2016. Information was collected from the clinical notes of each patients with mandible fractures. The demographic variables such as age, gender and clinical information included diagnosis, etiology, and anatomical distribution of fractures was assessed. RESULTS The total of 229 subjects had mandible fractures, out of which 209 were males and 20 were females. The mean age of the participants was 32,2±10. The major cause of fractures was assault 79% , followed by road traffic accident – 11%, sport injuries – 5%, accidents at work or home – 3%, other – 2%. Mandible fracture incidence were high during in August. By the time referred to a physician from day of injury were 1-5 days 72,1%, 6-10 days 25,7%, delayed more than 10 days were 2,2% of the cases. Unilateral fractures were 77,4%, bilateral fractures 21,7%. Mandible left side were 158 (65,9%) mostly injured. The most common fracture site was angle- 112 (53%), condyle- 58 (27,5%), body- 21 (9,9%), parasymphysis- 16 (7,6%) and at least common site were ramus- 2 (1%) and symphysis - 2 (1%) of mandible. Among multiple fractures most common sites were condyle-parasymphysis which 24 cases and angle – parasymphysis were 21 cases. CONCLUSION The following conclusions have been drawn from the foregoing study. The mandible fractures were more common in males 209 (91,3%) than females 20 (8.7%). Assaults were the most common cause of the fracture. 77,4% fractures were unilateral fractures. The most common site of fracture was mandible angle- 112 (53%) and common multiple fractures were condyle-parasymphysis. By the time referred to a physician from day of injury were 1-5 days 72,1%, 6-10 days 25,7%, delayed more than 10 days were 2,2% of the cases.

To evaluate the efficacy and safety of bevacizumab monotherapy or combined with laser versus laser monotherapy in Mongolian patients with visual impairment due to diabetic macular edema.Prospective, randomized, single-center, a 12 month, laser-controlled, clinical trial. Participants: One hundred twelve eligible patients, aged ≥18 years, with type 1 or 2 diabetes mellitus and best corrected visual acuity (BCVA) in the study eye of 35 to 69 Early Treatment Diabetic Retinopathy Study (ETDRS)letters at 4 m (Snellen equivalent: ≥6/60 or ≤6/12), with visual impairment due to center-involved diabetic macular edema (DME). Methods: Patients were randomized into three treatment groups:(I) intravitreal bevacizumab monotherapy (n=42), (II) intravitreal bevacizumab combined with laser (n=35), (III) laser monotherapy (n=35). Bevacizumab injections were given for 3 initial monthly doses and then pro re nata (PRN) thereafter based on BCVA stability and DME progression. The primary efficacy endpoints were the mean change in BCVA and central retinal subfield thickness (CRST) from baseline to month 12.Bevacizumab monotherapy or combined with laser were superior to laser monotherapy in improving mean change in BCVA letter score from baseline to month 12 (+8.3 and +11.3 vs +1.1 letters; both p<0.0001). There were significant difference detected between the bevacizumab and bevacizumab combined with laser treatment groups (p=0.004). At month 12, greater proportion of patients gained ≥10 and ≥15 letters and with BCVA letter score >73 (Snellen equivalent: >6/12) with bevacizumab monotherapy (23.8% and 7.1% and 4.8%, respectively) and bevacizumab + laser (57.1% and 28.6% and 14.3%, respectively) versus laser monotherapy. The mean central retinal subfield thickness was significantly reduced from baseline to month 12 with bevacizumab (−124.4 μm) and bevacizumab + laser (−129.0 μm) versus laser (−62.0 μm; both p<0.0001). Conjunctival hemorrhage was the most common ocular events. No endophthalmitis cases occurred.Bevacizumab monotherapy or combined with laser showed superior BCVA improvements over macular laser treatment alone in Mongolian patients with visual impairment due to diabetic macular edema.

Introduction: Various modalities oftechniques from standard discectomy,microdiscectomy, percutaneous discectomy,and transforaminal endoscopic discectomyhave been in use for lumbar intervertebraldisc prolapse1. The access to spine is keptto a minimum without stripping paraspinalmuscles minimizing muscle damage bytransforaminal endoscopic approach2.Currently in the population of the Mongoliabeen increased of the spinal nerve rootcompression, which are resulting in lumbardisc pathological changes. In other developedcountries has been successfully introducingthe spine endoscopic surgery use for thatpathological changes. In regard to our countryhad not yet implemented for until now asthese high technological surgeries3. Spinesurgery department team of the GrandMedhospital had successfully introduced that thespine endoscopic surgery.Materials and Methods: We performedtransforaminal endoscopic lumbardiscectomy surgeries on patients age of 24,38, 78 on July/23/2016 All patients withsingle nerve root compression due to Lumbardisc herniations, including sequestrated ormigrated and selected central disc at L4-5. All patients had preoperative MRI andpostoperative MRI to check the adequacy ofdecompression. All patients were operatedby 18-mm ports of the S-Gun endoscopicequipments. Procedure had done under localanesthesia. Postoperatively, all patients weremobilized as soon as the pain subsided anddischarged within 24-48 h post-surgery.Patients were followed up at 2, 6 weeks.Results: The mean follow up was 2-6weeks. The average surgical time was 70min (range 25-210 min). Average blood losswas 20-30 ml. Postoperative MRI showedcomplete decompression. All of patients hadgood-to-excellent results and straight raisingleg test (Lasegue) were 90/90 respectively.All patient is preoperatively visual analogyscale was 8±1 and then became to 1±1.Conclusion: Microendoscopic discectomyis minimally invasive procedure fordiscectomy with results of this procedure areacceptable safe and effective. However, forthis technique has required to do accuracyand experienced surgeon.