1.Iron Metabolism Indicators in Relation to Metabolic Syndrome
Yansanjav D ; Nyamdorj D ; Enebish S ; Bolortsetseg Z ; Juramt B ; Munkhbayarlakh S ; Uurtuya Sh
Mongolian Journal of Health Sciences 2026;92(2):110-114
Background:
Metabolic syndrome (MetS) has been shown to be associated with multiple factors, including central obesity, insulin resistance, lipid metabolism disorders, and elevated blood pressure, thereby increasing the risk of cardiovascular disease and type 2 diabetes. In recent years, the prevalence of MetS has risen sharply worldwide, affecting about one-third of the global population, becoming a major public health concern. Although several studies on MetS have been conducted in Mongolia, research investigating the relationship between iron metabolism and MetS, particularly among men who are most affected, is limited. This formed the basis for the present study.
Aim:
To investigate selected indicators of iron metabolism in men with and without MetS.
Materials and Methods:
A total of 227 men aged 30-60 years from Ulaanbaatar were included in this study. Participants were classified into two groups: MetS (case group) and non-MetS (control group). According to the British Columbia “High Ferritin and Iron Overload – Investigation and Management” (2021) guidelines, serum ferritin levels were categorized into three groups: <300 ng/mL as normal ferritin, 300–600 ng/mL as hyperferritinemia, and >600 ng/mL as iron overload.
Result:
The mean age of the participants was 45.3±8.3 years. Based on the 2009 JIS criteria for MetS (five components), 38.8% (n=88) had MetS and 61.2% (n=139) were without MetS. According to the British Columbia guidelines, 46.7% (n=106) had normal serum ferritin, 33.9% (n=77) had elevated ferritin, and 19.4% (n=44) had iron overload. When serum iron-related proteins were analyzed by group, the ferritin levels ranged from 33.30 to 1330.00 ng/mL with a mean of 320.34 in the non-MetS group, and from 43.10 to 1044.00 ng/mL with a mean of 378.28 in the MetS group (F=3.957, Sig=0.049), indicating a statistically significant difference in ferritin levels between the two groups. Other iron metabolism indicators, including serum iron, transferrin saturation (TSAT%), Unsaturated iron binding capacity (UIBC), Total iron binding capacity (TIBC), and hepcidin, did not show statistically significant differences between groups.
Conclusion
Among the indicators of iron metabolism, only serum ferritin levels showed a statistically significant difference between men with and without MetS. Other indicators did not differ significantly, highlighting the need for further detailed investigation.
2.Evaluation of quality of life and treatment outcome among stroke patients with dysphagia
Mandula ; Ankhbold G ; Bolortsetseg Z ; Baljinnyam A ; Munkhbayarlakh S
Mongolian Medical Sciences 2019;188(2):12-16
Background:
In worldwide, 16.9 million cases of stroke were reported in 2010. It has increased by 68% since 1990. In 2016, there were 5.5 million deaths attributable to cerebrovascular disease worldwide (2.7 million deaths from ischemic stroke and 2.8 million deaths from hemorrhagic stroke). Furthermore, dysphagia is one of the most common complication and occurs 35-78% of patients with stroke. Specifically, dysphagia occurs in 51-100% of the brain stem stroke patients. Moreover, it could be the independent factor to predict mortality. In other words, it directly impacts the quality of life and decreases social activity.
Incidence of cardiovascular disease and stroke have been increasing related to instability of economy,
urbanization, bad lifestyle and stress. As a result of that, dysphagia has increased as well and is becoming one of the pressing issue of health care. It results malnutrition and prolonged the hospital stays. Unfortunately, its diagnosis and treatment are still not clearly defined yet.
Many researchers have investigated patients’ treatment outcome using a single treatment. In other word, researchers have studied the comparison of the separate results of electric stimulation and traditional swallowing therapies. In this study, we studied the results of combination therapy of traditional swallowing and muscle stimulation, and we aimed to identify the benefits of the combined therapeutic approach and to propose the effective, non-invasive methods for patients.
Objective:
We aimed to study treatment outcome and quality of life among stroke patients with dysphagia.
Material and Methods:
The study was conducted on a hospital-based, cross-sectional method. Study participants were obtained from Affiliated Hospital of Inner Mongolian University for the Nationalities between July 2018 and March 2019. All patients were divided into the three treatment groups. 150 dysphagic patients were evaluated by Swallowing Related Quality of Life (SWL-QOL) Scale before and after the treatment.
Results:
In total, 150 participants (mean age=59.70±9.55 years) aged between 34-77 were obtained in this study.
There were no statistically significant differences between the three groups in age (p=0.609).The data showed statistically significant positive treatment effect for all three groups (p=0.0001).The SWAL-QOL score was 39.25±3.50 in A group, 39.10±3.54 in B group, 42.12±4.55 in C group after the treatment. The SWAL-QOL score shows statistically significant difference, after the treatment (p=0.0001).
Conclusions
Rehabilitation treatment combined with neuromuscular electrical simulation appears better outcome than nerve or muscular stimulation combined with rehabilitation among stroke patients with dysphagia.
Result Analysis
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