Objective To observe the correlations of pontine biological indicators on fetal brain median sagittal MRI with gestational week.Methods Data of head MRI of 226 normal fetuses without obvious abnormalities of central nervous system(normal group)and 17 fetuses with abnormalities(abnormal group)at gestational age of 23 to 38 weeks were retrospectively analyzed.Pontine biological indicators based on median sagittal MRI were obtained,including pons anteroposterior diameter(PAD),total pons area(TPA),pontine basal anteroposterior length(AP),pontine basal cranio-caudal length(CC),basis pontis area(BPA)and pontine angle of midbrain(MAP).According to the gestational week,the fetuses of normal group were divided into 8 subgroups.The distributing ranges of pontine biological indicators at different gestational weeks were analyzed,and the correlations of pontine biological indicators with gestational week in normal group were explored,and the developmental status of fetal pons in abnormal group were assessed.Results In normal group,PAD,TPA,AP,CC and BPA all showed linear positive correlation(r=0.887,0.914,0.787,0.866,0.865,all P＜0.001),while MAP was not significantly correlated with gestational week(P＞0.05).Among 17 fetuses in abnormal group,abnormal PAD or TPA was found each in 8 fetuses,abnormal AP was observed in 14,abnormal CC was noticed in 3 and abnormal BPA was found in 11 fetuses.Conclusion Fetal pontine biological indicators such as PAD,TPA,AP,CC and BPA on median sagittal MRI were positively correlated with gestational week,hence being able to be used for evaluating fetal pontine development.

Objective:To investigate the risk factors and treatments of recurrent cesarean scar pregnancy (RCSP).Methods:A retrospective case-controlled study was performed in 48 cesarean scar pregnancy (CSP) patients in Shenzhen Maternity & Child Healthcare Hospital from January 2014 to December 2018. Recurrent group consisted of 12 patients with RCSP, while control group consisted of 36 patients experienced single CSP. The information of pregnancy, surgery and other factors of the two groups was compared.Results:Thickness of lower uterine segment in recurrent group was thinner than that in control group [(1.81±1.12) mm vs. (2.80±1.56) mm, P=0.031]. Dilation and curettage (D&C) was the main treatment method, and scar repair was the secondary treatment in these two groups. Patients may receive prophylactic uterine artery embolization (UAE) to prevent catastrophic bleeding during surgery when necessary. Totally 11 of 12 patients were cured in recurrent group, while all of 36 patients were cured in control group. Univariate analysis showed that artificial abortions ≥3 times ( P=0.007), type of CSP and thickness of lower uterine segment <3 mm ( P=0.013) had a significant correlation with the RCSP. Conclusion:Artificial abortions ≥3 times and thickness of lower uterine segment <3 mm were the independent risk factors of RCSP. D&C can be used as the first line treatment of RCSP, and prophylactic UAE should be performed when necessary.

Objective:To investigate the risk factors and treatments of recurrent cesarean scar pregnancy (RCSP).Methods:A retrospective case-controlled study was performed in 48 cesarean scar pregnancy (CSP) patients in Shenzhen Maternity & Child Healthcare Hospital from January 2014 to December 2018. Recurrent group consisted of 12 patients with RCSP, while control group consisted of 36 patients experienced single CSP. The information of pregnancy, surgery and other factors of the two groups was compared.Results:Thickness of lower uterine segment in recurrent group was thinner than that in control group [(1.81±1.12) mm vs. (2.80±1.56) mm, P=0.031]. Dilation and curettage (D&C) was the main treatment method, and scar repair was the secondary treatment in these two groups. Patients may receive prophylactic uterine artery embolization (UAE) to prevent catastrophic bleeding during surgery when necessary. Totally 11 of 12 patients were cured in recurrent group, while all of 36 patients were cured in control group. Univariate analysis showed that artificial abortions ≥3 times ( P=0.007), type of CSP and thickness of lower uterine segment <3 mm ( P=0.013) had a significant correlation with the RCSP. Conclusion:Artificial abortions ≥3 times and thickness of lower uterine segment <3 mm were the independent risk factors of RCSP. D&C can be used as the first line treatment of RCSP, and prophylactic UAE should be performed when necessary.

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100 u/L 24 months later and another 38 year-old patient underwent surgical operation of ovaries bilaterally before UAE. Conclusions Temporary amenorrhea may not mean ovarian dysfunction or failure. The probability of ovarian dysfunction or failure after UAE is low, which mainly occur in the peirmenopausal patients. Consideration of the probability of inducing early ovarian failure, caution should be taken for UAE on the patients having ovarian surgery before. (J Intervent Radiol, 2006, 15: 472-475)